Université catholique de Louvain (UCL-Bruxelles)
Louvain Drug Research Institute
(Department of Pharmaceutical Sciences)
Cellular and Molecular Pharmacology

Conferences and Public adresses
(selection since 1998) - Format is 4:3 unless indicated otherwise.

 Conférences en français -  Voordrachten in het Nederlands

These slides are for information purpose(s) only and cannot be reproduced or used in any form without the autorization of their author(s) and of the Director of the Cellular and Molecular Pharmacology Unit. Please, contact the Webmaster of the Unit.

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2019 | 2018 | 20172016 | 2015 | 2014 | 2013 | 2012 | 2011 | 20102009 | 200820072006 | 20052004 | 2003 | 2002 | 2001 2000 | before 2000

2019 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • The Right Antibiotic: Potential Clinical Outcomes and the Hidden Risks of a Low Cost Therapy: a critical analysis of the generics
    Anti-infective Master Class - Live Webcast
    24 October 2019
    PDF
    (version updated on 29 and 30 October 2019)

  • Intracellular models for antimicrobial R&D
    Global Antibiotic Research & Development Partnership (GARDP) Webinar
    9 July 2019
    PDF

  • Epidemiology, risk factors, and comorbidities associated with MRSA infections
    29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) - Industry integrated symposium: Walking a fine line to meet the clinical realities
    15 April 2019
    PDF

  • Activity of drug combinations against staphylococcal biofilms
    29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) - Session: Thinking out of the box to beat biofilms
    14 April 2019
    PDF

2018 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • Therapeutic Drug Monitoring (TDM) of antibiotics
    5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) - European Union of Medical Specialists (UEMS) joint congress in Laboratory Medicine, Antalya, Turkey, 10-13 October 2018
    PDF

  • Mechanims of resistance and susceptibility in Cystic Fibrosis (CF) pathogens
    41st European Cystic Fibrosis Conference, Belgrade, Serbia, 6-9 June 2018
    PDF

  • What makes an antibiotic the right antibiotic ?
    Bayer China Anti-infective Summit, Shanghai, China, 12 May 2018
    English version: PDF - Chinese version: PDF

  • Anti-infectives-biofilms interactions
    28ème Congrès National de la Société Tunisienne de Pathologie Infectieuse, Sousse, Tunisia, 27 April 2018
    PDF (English; see also an introductory presentation on biofilms in French: PDF [without video] - PDF [with video])


  • Contribution of new antibiotics to current and future challenges of main Gram-positive infections
    Are Gram-positive infections still a major concern to patients and Healthcare system?
    European Congress of Clinical Microbiology and Infections (ECCMID) 2018 - Integrated symposium - Madrid, Spain, 23 April 2018
    PDF

  • Skin and skin structures infections: various treatment approaches and pre-clinical profiles
    The evolving concept of bacterial infection in complicated patients
    European Congress of Clinical Microbiology and Infections (ECCMID) 2018 - Integrated symposium - Madrid, Spain, 21 April 2018
    PDF

  • Update on PK/PD of antibiotics applied to critically ill patients: Focus on ß-lactams and vancomycin
    18th Vietnam Association of Critical Care Medicine, Emergency and Clinical Toxicology Annual Congress, Da Lat, Viet Nam, 12 April 2018
    PDF (English) - PDF (Vietnamese)

  • Updating and optimizing carbapenem use in critically ill patients
    18th Vietnam Associatin of Critical Care Medicine, Emergency and Clinical Toxicology Annual Congress, Da Lat, Viet Nam, 12 April 2018
    PDF (Engllish)

2017 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • Discovery and exploitation of new targets for antibiotics: action on intracellular targets
    37ème Réunion Interdisciplinaire de Chimiothérapie Antiinfectieuse (RICAI), Paris, France, 19 December 2017
    PDF

  • Looking into the future: How to adapt antibiotic use based on pharmacokinetics and pharmacodynamics
    Seminar of the Centre Hospitalo-Universitaire (CHU) of Charleroi, Lodelinsart, Belgium, 19 December 2017
    PDF

  • Contribution of new antibiotics to today and tomorrow Gram-positive infections challenges
    ATHENA (Approaching THe sevErely iNfected pAtient) 2017 International Conference, Athens, Greece, 28-30 November 2017
    PDF

  • Advancing mRSA Management: A New Force for the Clinicians
    Conferences given in Singapore, Singapore (29 November 2017) and in Kuala-Lumpur, Malaysia (30 November 2017)
    PDF

  • Not All Fluoroquinolones ARE Equal
    Conferences given in Singapore, Singapore, 29 and 30 November 2017
    PDF


  • New agents for MRSA: recently released or in the pipeline
    30th International Congress of Chemotherapy and Infection (Symposium #2: MRSA: global epidemiology and treatment), Taipei, Taiwan, 24-27 November 2017
    PDF

  • Contribution of New and Future Antibiotics to Today and Tomorrow’s Gram-positive Infection Challenges
    MSD Global Infectious Diseases Forum, Madrid, Spain, 15-17 November 2017
    PDF

  • Fluoroquinolones: Parenteral use
    6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
    PDF

  • Branded vs. generic of antibiotics: Evidence-based approach
    6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
    PDF

  • Three WHO Priority Pathogens: P. aeruginosa (critical), S. aureus (high), S. pneumoniae (medium)
    6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
    PDF

  • New antimicrobial agents for the management ofMRSA acute bacterial skin and skin structure infections (ABSSSI): focus on tedizolid
    Lecture given in the Gulf States (Dubai, Kuwai, Abu Dhabi) - 24-27 October 2017
    PDF


  • Pharmacokinetics, pharmacodynamics and toxicodynamics (how to boost efficacy, reduce toxicity, and mitigate resistance, with focus on aminoglycosides and oxazolidinones)
    Ribosomes & Antibiotics, University of Tartu, Tartu, Estonia, June 9-10, 2017
    PDF

  • Improving antibiotic targeting in vivo
    40th European Cystic Fibrosis Conference (ECFC; Symposium S19: Next generation susceptibility testing - what works?), European Cystic Fibrosis Sociey (ECFS)? Sevilla, Spain, 7-10 June 2017
    PDF

  • Modulating Intracellular Antimicrobial Activity
    ASM Microbe 2017 (Symposium: Pharmacodynamics in the intracellular space), New Orleans, LA, June 1-5,2017
    PDF

  • The general Concepts of Pharmacokinetics
    ASM Microbe 2017 - Workshop, New Orleans, LA, June 1-5, 2017
    PDF

  • Novel therapies and the role of early switch and early discharge protocols for management of MRSA infections.
    Integrated symposium: "Infections Due to MRSA: Walking a Fine Line to Meet Real World Expectations" - European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, 24 April 2017
    PDF

  • New antibiotics: action on intracellular targets
    Symposium "Discovery and exploitation of new targets for antibiotics" - European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, 24 April 2017
    PDF (16:9)

  • What do we know on PK/PD of ß-lactams ?
    Spring Symposium of the Belgian Society for Infectiology and Clinical Microbiology: "Parenteral antibiotics: from intensive to home dosing", Brussels, Belgium, 30 March 2017
    PDF

  • Tolerance and resistance to antibiotics in Pseudomonas aeruginosa, or how do bacteria play with their environment
    Research Seminar, Institute of Technology, University of Tartu, Estonia, 8 March 2017
    PDF

2016 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • Moxifloxacin safety data review
    Fluoroquinolones and Respiratory Tract Infections, Beijing, China, 18th December 2016
    PDF

  • Antibiotic resistance and global overview of the use of fluoroquinolones against S. pneumoniae
    The role of fluoroquinolones in managing S. pneumoniae, Singapore, 16th December 2016
    PDF

  • Tedizolid: a novel treatment for Gram + infections and its potential role in clinical practice
    Full presentation [with backup slides] in Jeddah, Audi Arabia, November 26, 2016
    PDF (for shorter presentations made in Jeddah [27/11/2016] and in Riyadh [28/11/2016], click here
    .

  • Antibiotics and biofilm: in vitro evidence and new clinical applications
    Séminaire de microbiologie et de maladies infectieuses, Université libre de Bruxelles (presented at the CHU St-Pierre, Brussels)
    PDF

  • The bug: known and hidden challenges of infections with Staphylococcus aureus
    IDWeek 2016 (annual meeting of the Infectious Diseases Society of America), New Orleans, LA, October 26-31, 2016
    PDF (this presentation has been updated on November 3, 2016)

  • Looking beyond clinical trials data ? An overview of new approaches in drug evaluation.
    1st Latin America Anti-infectives Forum, Cancun, Mexico, October 14-15, 2016
    PDF

  • In vitro models for the study of the activity of anti-infective agents against biofilms
    Antimicrobial resistance in microbial biofilms and options for treatment, Conference of the European Society for Clinicla Microbiology and Infectious Diseases (ESCMID), Ghent, Belgium, 5-7 October 2016
    PDF (this presentation contains original material published on November 3, 2016)

  • How active are antibiotics when directed towards bacteria hiding intracellularly? Do accumulation and subcellular disposition matter?
    3rd Global Microbiologists Annual Meeting, Portland, Oregon, United States, August 15-17, 2016
    PDF

  • Is the expression of catalase by Staphylococcus aureus protective or detrimental to the survival of the bacteria when exposed to H2O2 in broth or after phagocytosis by monocytes? Are we disproving a dogma or misinterpreting data?
    3rd Global Microbiologists Annual Meeting, Portland, Oregon, United States, August 15-17, 2016
    PDF

  • Are public campaigns effective to reduce antibiotic overconsumption ? Did we fail to provide what is needed by the general practitioner?
    3rd Global Microbiologists Annual Meeting, Portland, Oregon, United State, August 15-17, 2016 s
    PDF

  • Anti-staphylococcal activity of antibiotics in biofilm and host cell
    Virulence and resistance in Staphylococcus aureus 2016: State of the art. ESCMID Postgraduate educational course, Lyon, France, 28 June-1 July 2016
    PDF

  • Intracellular bacterial infections: why are antibiotics poorly efficient and can we do something about it ?
    Department of Chemistry and Biochemistry, University of Notre-Dame, Indiana, United States, 15 June 2016
    PDF

  • Study of intracellular activity of antibiotics: significance for the clinical practice
    XVIII International Congress «Antimicrobial Therapy», Moscow, Russia, 25-27 May 2016
    PDF (English) - PDF (Russian)

  • New forces in the managment of methicillin-resistant Staphylococcus aureus (MRSA)
    Anti-infective Seminar II: Hospital Infections, Singapore, 22 March 2016
    PDF

  • Fluoroquinolones: are they all the same (or not) ?
    Anti-infective Seminar I: Community-acquired infections, Singapore, 22 March 2016
    PDF

  • Pneumonia: not just a Gram-negative issue
    Vietnam workshop (held during the 10th Asia Respiratory Tract Forum), Taipei, Taiwan, 20 March 2016
    PDF

  • What makes an antibiotic the right antibiotic (a story around respiratory tract infections) ?
    10th Asia Repiratory Tract Infections Forum, Taipei, Taiwan, 19-20 March 2016
    PDF



2015 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • New antibiotics: do we have them and how shall we pay for them ?
    Internal Seminar of the Cellular and Molecular Pharmacology group, Louvain Drug Research Institute, Brussels, 11 December 2015
    PDF

  • “Generics of antibiotics:Evidence-based approach”
    Bayer Round-Table, Medellin, Colombia, 2 December 2015
    PDF

  • The new antibiotics: useful improvement of our current armamentarium ... but can we pay for them?
    Universitad de Antioquia (Faculty of Medicine), Medellin, Colombia, 1 December 2015 (this presentation is focused on the US Regsitration and breakpoints)
    PDF

  • The new antibiotics: useful improvement of our current armamentarium ... and can we pay for them?
    Séminaire du service des soins intensifs, Cliniques universitaires St-Luc, Bruxelles, Belgium, 26 November 2015 (this presentation is focused on the European Registration and breakpoints)
    PDF

  • Colistin: news from an old drug
    Séminaire du service des soins intensifs, Cliniques universitaires St-Luc, Bruxelles, Belgium, 19 November 2015
    PDF

  • Intracellular Activity of Antibiotics: the knowns, the uncertainties and the failures
    Pharmacokinetics UK (PK-UK), Chester, United Kigdom, 19 November 2015
    PDF

  • Generics of antibiotics: an evidence-based approach
    Anti-Infective Bayer Middle East Forum, Dubai, UAE, 5th November 2015
    PDF


  • MRSA in the Middle-East and Tedizolid (discovery & microbiology / pharmacokinetics / pharmacodynamics / pre-clinical safety)
    Anti-Infective Bayer Middle East Forum, Dubai, UAE, 5th November 2015
    PDF

  • Antibiotic (accelerated) discovery and (more) rational use: a change in (accepted) paradigms based on economics ?
    DRIVE-AB 2015 General Assembly Meeting, Uppsala, Sweden, October 15-16, 2015 (keynote introductory lecture)
    PDF

  • Colistin: what is new for an old antibiotic ?
    Groupe d'Etude de la Médecine (GLEM), Erasme Hospital, Brussels, Belgium, 14 October 2015
    PDF

  • Looking into the future: routine TDM for beta-lactams in ICU ?
    14th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, Rotterdam, The Netherlands, 14 October 2015
    PDF

  • The misuse of antibiotics in the management of respiratory infections and its consequences
    Master Class Vietnam-Indonesia, Geneva, Switzerland, 1 October 2015
    PDF

  • The European road map against antimicrobial resistance... (a changing paradigm for drug discovery and development ?)
    2d International Conference on Polymyxins, La Jolla, CA, 22-24 September 2015
    PDF


  • 24 years of ISAP: Achievements in the PK/PD field - A lecture In Memoriam Bill Craig
    ISAP Annual Meeting & post-ICAAC symposium, La Jolla, CA, September 21, 2015
    PDF

  • Pumps (almost) everywhere: Impact on resistance and pharmacokinetics
    Groue local d'étude de la médecine (Soins Intensifs), Brussles, Belgium, 26 June 2015
    PDF

  • Emerging antibiotic resistance
    26th Sigrid Jusélius International Symposium "Emerging Infections", Hanasaari Congress Center, Espoo–Helsinki, Finland, 7-10 June 2015
    PDF

  • Treatment of infections in an era of resistance: the return of the old antibiotics… temocillin – nitrofurantoin – minocycline – trimethoprim-sulfamethoxazole
    Certificat interuniversitaire de formation en maladies infectieuses, Liège, Belgium, 4 June 2015 (some slides are in French)
    PDF

  • Antibiotic research and development in the age of ‘superbugs’
    Lunch meeting at the European Parliament, Brussels, 27 May 1015
    PDF

  • New antibacterial drugs: the drug pipeline for Gram-positive bacteria
    Gause Institute of New Antibiotics, Moscow, Russia, 22 May 2015
    PDF

  • Drug pipeline for Gram-positive bacteria
    25th European Congress of Clinical Microbiology and Infectious Diseases ( Sympoisum: New antibacterail drugs), Copenhagen, Denmark, 25 April 2015
    PDF


  • Resistance to antibiotics: the rise of efflux…
    Seminar of the Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium, 23 April 2015
    PDF


  • Fluoroquinolones: are they all the same (or not) ?
    Lectures delivered at Kuala Lumpur and Pennang, Malaysia, 9-10 March 2015
    PDF


  • Product Safety and Quality: An act of social and ethical responsibility (a discussion about generic antibiotics)
    - Strategies of antibiotic choice for in-patient treatment, Nha Trang, Vietnam, 12 March 2015 - PDF
    - 9th Asian Respiratory Tract Forum, Ho Vhi Minh City, Vietnam, 7-8 March 2015 - PDF

  • Inhaled antimicrobial therapy: pharmacodynamics and risks for development of resistance
    6th International Symposium of KU Leuven “Pulmonary infections” - February 26-28, 2015, Leuven (Louvain), Belgium, 27 February 2015
    PDF

  • Generics of antibiotics: Are you sure of what you get ?
    Seminar of the Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium, 8 January 2015
    PDF


2014 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

  • Antibiotic efflux pumps: from biology to clinical implications (and applications ?)
    Thematic week "Antibiotic Resistance", Université de Liège, Liége, Belgium, 4 December 2014
    PDF
    Survey of antibiotic efflux transporters in bacteria:
    up to 2002: Van Bambeke et al. J. Antimicrob. Chemother. 2003;51:1055-1065 [open access]
    up to 2008: Li & Nikado, Drugs 2009;69:1555-1623 [authors' copy]

  • The major mechanisms of resistance to aminoglycosides, macrolides, and fluoroquinolones
    2014 ISF Stephen F. Lowry Colloquium - Intersection between Virulence and Antimicrobial Resistance in the ICU, Paris, France1-3 December 2014
    PDF

  • Product Safety and Quality: An act of social and ethical responsibility (a discussion about generic antibiotics)
    Anti-Infective Bayer Middle East Forum, Dubai, United Arab Emirates, 7 November 2014
    PDF

  • Community-acquired LRTIs in Middle East: an update from microbiology to pharmacology and toxicology
    Anti-Infective Bayer Middle East Forum, Dubai, United Arab Emirates, 7 November 2014
    PDF

  • Optimisation of therapy in Gram-negative infections: TEMOCILLIN
    ESCMID (European Society of Clinical Microbiology and Infectious Diseases) conference on reviving old antibiotics, Vienna, Austria, 22-24 October 2014
    PDF

  • Antibiotic Resistance Acquisition
    Good Bugs - Bad Bugs - XXX Rocourt Neonatology Meeting, Seraing, Belgium, 14 June 2014
    PDF

  • Susceptibility trends in pneumonia pathogens and current prescribing
    24th European Congress of Clinical Microbiology and Infectious Diseases (Symposium: "Optimising diagnosis and appropriate antibiotic prescribing in pneumonia"), Barcelona, Spain, 12 May 2014
    PDF

  • The (EU) authorities & their antibiotic development policy: a changing paradigm
    Bayer Anti-infective Therapies Symposium: Advancing Todays' Practice and Preparing The Future, Reet, Belgium, 15 May 2014
    PDF

  • In vitro models for the study of antibiotic PK/PD in biofilms
    24th European Congress of Clinical Microbiology and Infectious Diseases (Symposium: "Exploring and treating biofilms"), Barcelona, Spain, 11 May 2014
    PDF

  • New approaches to antibiotic therapy in Gram Gram-positive infections
    24th European Congress of Clinical Microbiology and Infectious Diseases (Integrated Symposium: "Perspectives on the evolution and dissemination of Gram-positive organisms: a global challenge"), Barcelona, Spain, 10 May 2014
    PDF

  • Why monitoring beta-lactams on line ?
    Kick-off meeting of the MON4STRAT programme supported by the European Union (FP7), Liège, Belgium, 31 March-1 April 2014
    PDF
  • Generics of antibiotics: are you sure of what you get (with a discussion about overconsumption and economy of low cost antibiotics) ?
    • Séminaire de médecine interne, CHU Mont-Godinne/Dinant, Yvoir, Belgium - 2 April 2014 (with updates of all links) - PDF
    • 8th Asian Respiratory Tract Forum, Jakarta, Indonesia - 29 March 2014 - PDF
    • Séminaire de microbiologie-maladies infectieuses, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium - 22 January 2014 - PDF
    • Séminaire interdisciplinaire de pathologie infectieuse, Grand Hôpital de Charleroi, Charleroi, Belgium - 11 February 2014 - PDF

  • Ceftaroline: a new antibiotic for your patients ?
    Séminaire interdisciplinaire de pathologie infectieuse, Grand Hôpital de Charleroi, Charleroi, Belgium - 11 February 2014
    PDF

2013 (by reverse chronological order)

  • In vitro pharmacodynamic models for the study of antibiotic activity against bacterial biofilms
    1st meeting of the Belgian Interdisciplinary Biofilm Research Group, Louvain-la-Neuve, Belgium, 20 December 2013
    PDF

  • Antibiotic efflux pumps: from biology to clinical implications (and applications ?)
    Thematic week "Antibiotic Resistance", Université de Liège, Liege, Belgium, 4 December 2013
    PDF
    Survey of antibiotic efflux transporters in bacteria:
    up to 2002: Van Bambeke et al. J. Antimicrob. Chemother. 2003;51:1055-1065 [open access]
    up to 2008: Li & Nikado, Drugs 2009;69:1555-1623 [authors' copy]

  • Guidelines & PK/PD for Pneumonia, Resistance (adults vs children) and "Last Year Review" in Respiratory Tract Infections
    INSPIRATION: Global Perspectives and Local Insights in Infection Management, Jeddah, Saudi Arabia, 15 November 2013
    "Guidelines & PK/PD" PDF // "Resistance" PDF // "Last Year" PDF

  • Antibiotics case study: How can re-studying old drugs improve existing ones ?
    5th Annual Late Phase Leaders Forum, Brussels, Belgium, 12-14 November 2013
    PDF

  • Generics of antibiotics: Are you sure of what you get ?
    Groupes de Gestion de l'Antibiothérapie (CHU Liège - CHU Citadelle), Liège, Belgium, 7 November 2013
    PDF

  • Ceftaroline: a new antibiotic for your patients ?
    Groupes de Gestion de l'Antibiothérapie (CHU Liège - CHU Citadelle), Liège, Belgium, 7 November 2013
    PDF

  • Guidelines in Community-acquired Pneumonia, Resistance (adults vs children) and "Last Year Review" in Respiratory Tract Infections
    INSPIRATION: Global Perspectives and Local Insights in Infection Management, Moscow, Russia, 12 October 2013
    "Guidelines" PDF (English) - PDF (Russian) // "Resistance" PDF (English) - PDF (Russian) // "Last Year" PDF (English) - PDF (Russian)

  • Antibiotic resistance by efflux: from molecular aspects to cinical impact
    Seminar at the Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 16 September 2013
    PDF

  • Approaches to Current and Future Treatment Options in Gram-positive Infections
    Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Denver, CO, 10 September 2013
    (Satellite meeting: Therapy for MRSA Infections in the Evolving Healthcare Environment)
    PDF

  • Therapeutic options for MRSA: what next beyond vancomycin and linezolid ?
    3rd Shanghai International Congress on Clinical Microbiology and Antimicrobial Chemotherapy (SICCMAC), Shanghai, China, 23-25 August 2013
    PDF (English) - PDF (Chinese)


  • Thoughts on generic product properties that might impact the clinical effect: what are the downsides ?
    Bayer-China Advisory Board, Beijing, China, 26 June 2013
    PDF (English) - PDF (Chinese)


  • Treatment strategies and antibiotic pipeline for treatment of infections with resistant Gram-negative bacteria
    Antioticabeleidsgroep AZ St-Jan, Brugge, Belgium, 13 June 2013
    PDF

  • Global Antibiotic Resistance in Respiratory Tract Infections
    • Vietnamese Master Class OM Pharma, Geneva, Switzerland, 3 June 2013
      PDF (English)

    • Chinese Master Class OM Pharma, Geneva, Switzerland, 2 May 2013
      PDF (English) - PDF (Chinese)


  • Antibiotics in bone and joint infections
    Orthopaedica Belgica 2013 & Belgian Society of Clinical Microbiology and Infectious Diseases, Spa, Belgium, 25 April 2013
    PDF

  • Prescribing guidelines in CAP: a global vision with a Russian perspective
    INSPIRATION: critical issues in infection management, Moscow, Russia, 6th April 2013
    PDF (English) - PDF (Russian)


  • Pharmacological approaches to the discovery and optimized development of novel antibiotics
    National University of Vietnam - International University, Ho Chi Minh, Vietnam, 25 March 2013
    PDF

  • Guidelines in Community-Acquired Pneumonia (CAP) and Chronic Obstructive Lung Disease (COPD): from diversity to logics
    7th Asian Respiratory Tract Infection Forum, Ho Chi Minh City, Vietnam, 24 March 2013
    PDF

  • Understanding antibiotic PK/PD profiles to optimize patient outcomes
    7th Asian Respiratory Tract Infection Forum, Ho Chi Minh City, Vietnam, 23 March 2013
    PDF

  • Moxifloxacin: PK/PD and safety profile
    Bayer Region EMEA Avelox Forum, Dubai, United Arab Emirates – 22 March 2013
    PDF

  • Future design of (comparative) clinical trials or how to bring antibiotics to the bed side
    Ceftaroline Fosamil Speaker Summit (The Role of Ceftaroline in our Antibiotic Armamentarium), London, UK, 7 March 2013
    PDF

  • From new bacterial targets to clinical applications
    WINP Tech 2012 (Workshop on Innovative and Pionnering Technologies), Kobe University, Kobe, Japan, 19 February 2013
    PDF

2012 (by reverse chronological order)

  • Merging systems pharmacology with PK/PD analysis to enhance drug discovery: the case of novel antibiotics
    4th PK-PD Summit - Frankfurt, Germany, 27-29 November 2012
    PDF

  • Comparative studies with antibiotics: Why should we change the rules?
    Late Phase Leaders Forum, Vienna, Austria, 8-10 October 2012
    PDF

  • Guidelines in lower respiratory tract infections: from diversity to logics
    Commonwealth of Independent States (CIS) Consensus Meeting on Respiratory Tract Infections ("Inspiration" ), Kiev, Ukraine, 22-23 September 2012
    PDF (English) - PDF (Russian)


  • Aminoglycosides: a new look at old but probably faithful antibiotics
    Invited Lecture - Department of Chemistry and Biochemistry, University of Notre-Dame, Notre Dame, Indiana, 17 September 2012
    PDF


  • Hepatic Safety of Common Antibiotics
    52d Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA, 9-12 September 2012
    PDF

  • Intra- and Extra-cellular Activities of Anti-Infective Agents
    52d Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA, 9-12 September 2012
    PDF

  • Perspectives in antimicrobial agents
    European Society of Clinical Pharmacy, Leuven (Louvain), Belgium, 1 June 2012
    PDF

  • EUCAST breakpoints
    Belgian Institute of Public Health (ISP/WIV), Brussels, Belgium, 31 May 2012
    PDF

  • Intracellular bacteria and antibiotics: S. aureus, L. monocytogenes and P. aeruginosa
    Institut national de la recherche agronomique (INRA), Tours, France, 15 February 2012
    PDF

  • Antibiotic efflux: from discovery to epidemiological, clinical, and veterinary impact
    Institut national de la recherche agronomique (INRA), Tours, France, 15 February 2012
    PDF

  • EUCAST breakpoints
    13th Congress of the Lebanese Society for Infectious Diseases and Clinical Microbiology, Beirut, Lebanon, 2-4 February 2012
    PDF

  • Guidelines in infectious diseases: from diversity to logics (a study about CAP guidelines)
    13th Congress of the Lebanese Society for Infectious Diseases and Clinical Microbiology, Beirut, Lebanon, 2-4 February 2012
    PDF


2011 (by reverse chronological order)

  • Moxifloxacin safety data review
    8th Forschungswerkstatt Moxifloxacin 2011, Leverkusen, Germany, 18 November 2011
    PDF


  • But where does the Pharmaceutical Industry go ... and Universities in all that business ?
    A3P Symposium Belgium, Spa, Belgium, 16 November 2011
    PDF


  • Discovery of new antibiotics: Why and some approaches (with a short presentation of Belgium and of the Université catholique de Louvain)
    International University, Vietnam National University, Ho Chi Minh City, Vietnam, 10 October 2011

    PDF

  • Colistin: from structure to clinical use via microbiology, PK/PD, and toxicology
    Bach Mai Hospital, Hanoi, Vietnam (within the context of a cooperative programme between Wallonie-Bruxelles International and the University of Pharmacy, Hanoi, Vietnam), 6 October 2011
    PDF


  • Optimising treatment based on PK/PD principles
    Evolving Antibacterial Therapy - 30 years of clinical experience, 24-25 September, Istanbul, Turkey
    PDF

  • Towards clinical Applications of PK-PD in specific situations
    51th Interscience Conference onf Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL. - ICAAC/ISAP Workshop - 16 September 2010

    PDF


  • Guidelines in lower respiratory tract infections: from diversity to logics
    Latin-America consensus meeting on Respiratory Tract Infections ( "Inspiration" ), Rio-de-Janeiro, Brazil, 28-30 July 2011
    PDF


  • Antibiotic resistance: are we heading for failures ?
    36th Annual Meeting of the International Urogynecological Association, Lisbon, Portugal, 29 June 2011
    Symposium "The guidelines offer more than antibiotics to manage recurrent urinary tract infections"

    PDF

  • Towards rational international antibiotic breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)
    1st International & 12th Iranian Congress of Microbiology, Kermanshah, Iran, 23-26 May 2011
    PDF

  • Hunting intracellular bacteria with antibiotics
    1st International & 12th Iranian Congress of Microbiology, Kermanshah, Iran, 23-26 May 2011
    PDF


  • Improving usage by guidelines: a critical view
    21st European Congress of Chemotherapy and Infectious Diseases & 27th International Congress of Chemotherapy, Milan, Italy, 7-10 May 2011
    Symposium: Bridging the gap of innovation – what we all could do ?
    PDF


  • Strategies to combat resistance: Focus on pharmacokinetics/ pharmacodynamics with applications to beta-lactams and a few words on colistin
    - Academy for Infection Management, India -- Mumbai (12-02) -- Chennai (13-02) -- Bangalore (14-02) -- Kolkata (15-02) -- Delhi (16-02) -- calculator (beta-lactams "concentration vs time" after IV bolus) (available soon)
    - International Critical care Congress 2001(CRITICARE 2001), Delhi 18 February 2011 - PDF (this set of slides contains also data on vancomycin)

2010 (by reverse chronological order)

  • Respiratory fluoroquinolones: Benefit-Risk profiles
    Belgische Vereniging voor Pneumologie – Société belge de pneumologie, Antwerp, 27 November 2010
    PDF

  • Towards clinical Applications of PK-PD in specific situations
    50th Interscience Conference onf Antimicrobial Agents and Chemotherapy (ICAAC), Boston, Mass. - ICAAC/ISAP Workshop - 11 September 2010
    PDF

  • Hunting intracellular bacteria with antibiotics
    Invited Lecture - Department of Chemistry and Biochemistry, University of Notre-Dame, Notre Dame, Indiana, 9 September 2010
    PDF

  • How do antibiotics play with multidrug transporters in eucaryotic cells ?
    462nd W.E. Heraeus Seminar, Jacobs University, Bremen, Germany, 9 July 2010
    PDF

  • Antibiotic transporters in Pseudomonas aeruginosa and Streptococcus pneumoniae: impact on resistance and clinical significance
    (Introductory comment: why do we need but will have difficulties in getting new antibiotics)
    462nd W.E. Heraeus Seminar, Jacobs University, Bremen, Germany, 9 July 2010
    PDF


  • Antibiotic efflux in procaryotic and eucaryotic cells: from molecular mechanisms to pharmacological consequences
    Institut National de la Recherche Agronomique, Toulouse, France, 21 May 2010
    PDF


  • Impact of the antibiotic treatment on resistance of Pseudomonas aeruginosa in nosocomial pneumonia, or "Pseudomonas in Brussels in 2010"
    Séminaire de microbiologie et maladies infectieuses, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium, 24 March 2010
    PDF

  • Intracellular Killing: Where’s the Bug? Where’s the Drug?
    Gordon Research Conference "New Antibacterial Discovery & Development", Galveston, TX, 18 March 2010
    PDF


  • Update on new antibiotics in Belgium
    Seminar for Clinical pharmacists, Université catholique de Louvain & Cliniques universitaires St-Luc, Brussels, Belgium, 25 January 2010
    PDF

2009 (by reverse chronological order)

  • Aminoglycosides: What have we learned about toxicity ?
    Infectious Diseases Society of America (IDSA) 47th Annual Meeting, Philadelphia, PA, 29 November 2009
    (Symposium # 153: Back to the Future: The Aminoglycosides are Here Again)
    PDF


  • ABC transporters: from survival to resistance (or vice-versa)
    Colloque ABC franco-belge / ABC French-Belgian Colloquium, Paris, France, 14 October 2009
    PDF

  • Iron metabolism and medical needs: a view from Academia
    Iron Therapy Master Class, Zürich, Switzerland, 13-15 October 2009
    PDF

  • Efflux pump inhibitors to restore antibiotic efficacy
    ESCMID/FEMS Conference: "From Microbial Pathogenesis to the Discovery of Antivirulence Drugs", Les Diablerets, Switzerland, 4-8 October 2009
    PDF


  • Administration of beta-lactams by continuous infusion: when, how, and for which molecules ?
    49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA (Meet-the-Experts – session 202. Optimization of Beta-Lactams: Continuous and Prolonged Infusions versus Standard Regimens) - 14 September 2009
    PDF


  • Updates on treatment of Staphylococcus aureus / MRSA
    26th Annual Meeting of the Scandinavian Society of Antimicrobial Chemotherapy, Tromsoe, Norway, 5 September 2009
    PDF

  • Safety of antibiotics used in respiratory tract infections: benefit-risk profile of moxifloxacin
    2009 Annual Meeting of the Finnish Society for Infectious Diseases (satellite symposium), Helsinki, Finland, 25 August 2009
    PDF

  • Intracellular infection and activity of antibiotics: concepts and examples with Staphylococcus aureus and Listeria monocytogenes
    Lecture given at The Turku Center for Immunology, National Public Health Institute, Turku, Finland, 24 August 2009
    PDF


  • Antibiotic selection in community-acquired pneumonia (CAP): appropriate benefit-risk profiles
    7th Forschungswerkstatt Moxifloxacin 2011, Leverkusen, Germany, 26 June 2011
    PDF


  • Collateral effects of antibiotics: adverse effects and drug interactions
    26th International Congress of Chemotherapy and Infection (Meet the Experts session ME-41), Toronto, Ont., 20th June 2009
    PDF

  • New antimicrobials
    27th Annual meeting of the European Society for Paediatric Infectious Diseases (ESPID), Brussels, Belgium, 12 June 2009
    PDF


  • Adopting EUCAST breakpoints in countries currently on CLSI breakpoints and some personal thinking…
    19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki, Finland, 18 May 2009
    PDF

  • Colistin pharmacokinetics/pharmacodynamics with an introduction and comments about reasonable uses
    19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki, Finland, 17 May 2009
    PDF

  • Antibiotic transporters: Clinical Implications
    Gordon Reserach Conference "Efflux Transporters", Galveston, TX, 26 March 2009
    PDF


  • Antibiotics for Community-acquired pneumonia (CAP): appropriate benefit-risk profiles
    - 5th Forum on Respiratory Tract Infections, Sitges (Barcelona), Spain, 5 February 2009  PDF
    - Italian medical educational meeting, Leverkusen, Germany, 6 March 2009  PDF
    - 7 Forschungswerkstatt Moxifloxacin, Leverkusen, Germany, 26 June 2009 PDF

  • Doripenem vs meropenem: a summary of international and Belgian published data
    Brussels, Belgium, 2 February 2009
    PDF

  • Deciphering the activity of antibiotics against intracellular Staphylococcus aureus with the help of PK/PD (pharmacokinetics/pharmacodynamics)
    Seminar held at the Institut für Medizinische Mikrobiologie, Universitätsklinikum Münster, Germany, 15 January 2009
    PDF

2008 (by reverse chronological order)

  • Safety of moxifloxacin with special reference to the recent labelling change and benefit-risk ratio
    Lecture for Italian Infectious Diseases and Pulmonologists, Leverkusen, Germany, 2 december 2008
    PDF


  • New developments in anti-Gram positive treatments
    Société belge d'infectiologie et de microbiologie clinique/Belgische Vereniging voor Infectiologie en Klnische Microbiologie, La Hulpe, 6 November 2008
    PDF

  • Pharmacodynamics of antibiotics in cerebrospinal fluid (CSF): Principles and Consequences (factors predictive of efficacy)
    17ème Conférence de consensus en maladies infectieuses - Prise en charge des méningites bactériennes aiguës, Paris, 19 novembre 2008
    PDF (English version - pour une version française: cliquez ici)


  • Toxicodynamics
    Symposium in honor of Prof. W.A. Craig, University of Madison, School of Medicine and Public Health, Madison, WI, October 29, 2008
    PDF

  • How to target intracellular pathogens
    48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America(Symposium Pharmacokinetic/Pharmacodynamic - Factors in Treating Infection in Special Sites and/or Special Pathogens - session 53), Washington, DC, October 25, 2008
    PDF


  • Aminoglycoside nephrotoxicity: a paradigm in toxicodynamic research
    48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America (Symposium Toxicodynamics - session 72), Washington, DC, October 26, 2008
    PDF

  • Towards clinical Applications of PK-PD
    48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America (Workshop), Washington, DC, October 24, 2008
    PDF

  • Safety of moxifloxacin and its benefit-risk ratio in community setting
    Educational symposium at the occasion of the 2008 Annual Meeting of the European Respiratory Society, Berlin, Germany, October 6, 2008
    PDF


  • From erythromycin to telithromycin: two bullets for one target ... what makes the difference ?
    2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
    PDF

  • Chemotherapy and PK/PD of intracellular infections
    2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
    PDF

  • Aminoglycoside nephrotoxicity: a paradigm in toxicodynamic research
    2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
    PDF

  • Antibiotic transporters: from Discovery to Clinical Implications
    PhD's Day, Académie Bruxelles-Wallonie, Brussels, 20 May 2008
    PDF


  • Activity of antibiotics against intracellular S. aureus
    European Congress of Clinical Microbiology and Infection (ECCMID), Barcelona, Spain - 21 April 2008
    PDF

2007 (by reverse chronological order)

  • Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)
    Academy of Infection Management, Athens, Greece – 16 November 2007
    PDF


  • Towards clinical Applications of PK-PD
    47th Interscience Conference on Antimicrobial Agents and Chemotherapy (Workshops), Chicago, IL, September 16th, 2007
    PDF

  • Efflux as new challenge in antibacterial chemotherapy
    Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
    PDF

  • Inhibitors of efflux pumps: the long journey from procaryotes to eukaryotes
    Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
    PDF

  • Molecular bases for antibiotic resistance through efflux
    Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
    PDF

  • Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and some personal thinking…
    Hospital Vesale, Montigny-le-Tilleul, Belgium - May 22d, 2007
    PDF
    version française (Le Roeulx [9/11] et Liège [11/11 ])
    Nederlandse versie (Hasselt [4/6], Antwerpen [11/6], Destelgem [18/6])


  • Examining the interaction of drugs and membranes to improve selectivity
    Ehancing Screening Strategies with Cell-Based Assays, Informa-Life Sciences (Informa plc, London, UK), Munich, Germany - February 5-8th, 2007
    PDF

  • Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and some personal thinking…
    Seminar for AstraZeneca, Destelbergen, Belgium, January 15, 2007
    PDF

  • The bad and good uses of fluoroquinolones in urology
    Groupe local d'étude de la médecine (GLEM), Cliniques universitaires St-Luc, Brussels, Belgium - January 9, 2007
    PDF

2006 (by reverse chronological order)

  • Are intracellular drug concentrations relevant for efficacy ? A discussion about accumulation, efflux and activity …
    2006 Joint Fall Meeting of the Nederlandse Vereniging voor Medische Microbiologie & Vereniging voor Infectie Ziekten, Amsterdam, The Netherlands, November 16, 2006
    PDF

  • Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and some personal thinking…
    "Les midis de l'Infectiologie", Centre hospitalo-universitaire, Université de Liège, Belgium, November 14, 2006
    PDF

  • Quinolones, macrolides, beta-lactams, glycopeptides ... and a few others against resistant S. aureus
    3d International Symposium on Gram-positive Infections, Niagara-on-the Lake, Ontario, October 9-11th, 2006
    PDF

  • Pharmacokinetics of Old and New Glycopeptides
    46th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, San Francisco, CA, September 27, 2006
    PDF

  • Pharmacodynamics of antibiotics as a means to improve and curb the emergence of resistance
    2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
    PDF

  • New antistaphylococcal agents: hopes and limitations
    2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
    PDF

  • Antibiotic restriction policies: are they applicable (and desirable) outside the western world ?
    2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
    PDF

  • Pharmacodynamics of antibiotics … From what you already knew about " optimizing activity " ... to what you didn't dare to ask about emergence of resistance...
    Joint Spanish-Belgian Intensive Care meeting, Barcelona, Spain, April 22, 2006
    PDF

  • Pharmacodynamics of antibiotics: Correlation between kinetics and activity
    4th Arab Symposium for Antimicrobial Agents / 16th National Tunisian Congress of Infectiology, Tunis, Tunisia, April 18th, 2006
    PDF

  • Aminoglycosides: a new look at old but probably faithfull antibiotics
    Research Lecture for Pfizer Central Laboratories, Groton, Conn., April 12, 2006
    PDF

  • Antibiotic combinations vs. monotherapy in critical care
    AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
    PDF

  • PK/PD modeling of antibiotics: Clinical Implications
    AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
    PDF

  • Pharmacodynamic indices in targeting therapy of critical infections
    AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
    PDF


  • PK/PD of antibiotics: from theory to applications in the real world...
    Joint Italian-Belgian Intensive Care meeting, Milan, Italy, March 18, 2006
    PDF

  • Use of cell lines to study specific aspects related to bacterial infections and antibiotic transport
    International Worshop on Cellular Models in Drug Development, London, UK, February 15, 2006
    PDF

  • Relationship between resistance, antibiotic policies, and clinical guidelines in the community: Government interventions on Antibiotic Policy in Belgium
    Libra Initiative European Summit, Brussels, Belgium, January 18, 2006
    PDF


2005
  • Models of antibiotic intracellular transport
    45th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, Washington, DC, December 19th, 2005

    PDF

  • How to choose an antibiotic for respiratory tract infections in 2005
    Barcelona, Spain, November 24th, 2005
    PDF

  • Antibiotic efflux pumps in eucaryotic cells: consequences for activity against intracellular bacteria
    Journée d'animation scientifique IFR 136 "Agents transmissibles et infectiologie - Mécanismes d’efflux et résistances aux agents thérapeutiques", Institut National de la Recherche Agronomique (INRA), Tours-Nouzilly, France, June 8th, 2005
    Web presentation - PDF
  • The pharmacological and microbiological basis of PK/PD: Why did we have to invent PK/PD in the first place ?
    24th International Congress of Chemotherapy, Manila, Philippines, June 5, 2005
    Web presentation - PDF

  • Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) - A report to the Interntaional Scociety of Chemotherapy (ICC)
    24th International Congress of Chemotherapy, Manila, Philippines, June 4, 2005
    PDF

  • Azalides revisited: why the single dose ?  The pharmacologist's answer
    24th International Congress of Chemotherapy, Manila, Philippines, June 4, 2005
    Web presentation - PDF



2004
  • Glycopeptides: how can a structural modification bring to a new life an old family of antibiotics ?
    Séminaire et Conférences du Département des Sciences Pharmaceutiques, Université catholique de Louvain, Brussels, Belgium, December 13th, 2004
    Web presentation - PDF

  • Collaborations on antibiotics with the Rega Institute
    Rega Institute 50th Anniversary, Katholieke Universiteit Leuven, Louvain, Belgium, October 9th, 2004
    Web presentation - PDF

  • Belgian Antibiotic campaigns (2000-2002)
    European Workshop on Antibiotic Campaigns, Brussels, Belgium, September 23-24, 2004
    Web presentation - PDF

  • Intracellular antibiotics
    World Conference on Magic Bullets - Celebrating Paul Ehrlich's 150th birthday, Nuremberg, Germany, September 9-11th, 2004
    Web presentation - PDF

  • Antibiotic efflux pumps in eucaryotic cells: consequences for activity against intracellular bacteria
    Cost B16 meeting (European Commission), Ghent, Belgium, May 28th, 2004
    Web presentation - PDF file

  • Setting-up of a 24 h model to evaluate the activity of antibiotics against intracellular forms of S. aureus infection
    King Pharmaceuticals Workshop, Prague,Czech Republic, May 4th, 2004
    Web presentation - PDF file

  • Vancomycin by continuous infusion ... Why and how ?
    GSK-Belgium satellite meeting - 14th European Congress of Chemotherapy, Prague, Czech Republic, May 3d, 2004
    Web presentation - PDF file

  • MRSA treatments: does the future shine ?
    GSK-Belgium satellite meeting - 14th European Congress of Chemotherapy, Prague, Czech Republic, May 3d, 2004
    Web presentation - PDF file

  • Nephrotoxicity of Aminoglycosides and Comparisons with Cis-Platinum
    American Association for Research in Otolaryngology, Annual Meeting - Presidential Symposium (Daytona Beach, FL),
    February 22, 2004
    Web presentation - PDF file



2003

2001


2000


before 2000

  • Fluoroquinolones: structure versus activity and toxicity. 
    Société Belge d’Infectiologie et de Microbiologie Clinique/Belgische Vereniging voor Infectiologie en Klinische Microbiologie, St.-Niklaas, Belgium, December 11, 1999

  • Fluoroquinolones : from structure to activity, 
    Internal training and education seminar for Bristol-Myers/Squibb, Brussels, Belgium, October 25, 1999

  •  Aminoglycoside nephrotoxicity: from molecular pharmacology and pathology to some clinical applications (only part of ythe slides shown are available), 
    University of Cincinnati Medical Center (Division of Nephrology & Hypertension), Cincinnati, Ohio, October 9, 1999

  • Intracellular infection : a journey from biology to therapy, 
    University of Cincinnati Medical Center (College of Pharmacy), Cincinnati, Ohio, October 8, 1999

  • In vitro toxicodynamic models to accelerate drug selection and safety assessment,
    9th Symposium of the International Society for Anti-infective Pharmacology, Birmingham, United Kingdom, July 3, 1999

  • Antibiotic use : is it time for a change ? My personal view, 
    Joint EMEA (European Agency for the Evaluation of Medicinal Products) / ISAP (International Society of Antiinfective Pharmacology), Uppsala, Sweden, June 10, 1999

  • Can computer modelling predict the intracellular activity of antibiotics, 
    Symposium “Computer modelling of antibiotic response”, 9th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Berlin, Germany, March 24, 1999

  • Intracellular anti-infectives: is it important for efficacy and do we need to care for toxicity?  
    1st workshop of the International Society of Antiinfective Pharmacology, Berlin, Germany, March 21,1999

  • Pharmacokinetics and Pharmacodynamics in action : a view from the patient, 
    1st workshop of the International Society of Antiinfective Pharmacology, Berlin, Germany, March 21,1999

  • Pharmacokinetic/ Pharmacodynamics in Drug Development and Evaluation 
    FDA / ISAP Workshop “Pharmacodynamics and the impact on antiinfective drug development”, Rockville, MD, March 1, 1999
    (Presidential address on behalf of the International Society of Antiinfective Pharmacology)

  • Problems arising from the use of modern antibiotics  
    Opening lecture at the Annual Meeting of the Portuguese Society for Microbiology and Infectious Diseases, Coimbra, Portugal, February 25, 1999

  • Antibiotic uptake in cells: do liposomes help ? 
    Symposium “"Pharmacological issues for antimicrobial Therapy using liposomes"
    38th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, San Diego, CA, September 25, 1998

  • Cultured cells models for the prospective assessment of anti-infective toxicity 
    Pharmacodynamics of Antiinfective Drugs as a Way to accelerate Drug Pre-clinical and Clinical Development, International Society of Antiinfective Pharmacology, San Diego, CA, September 23, 1998

  • Defining the requirements for an intracellular antibiotic, 
    Pharmacodynamics of Antiinfective Drugs as a Way to accelerate Drug Pre-clinical and Clinical Development, International Society of Antiinfective Pharmacology, San Diego, CA, September 23, 1998

  • Antibiotic distribution and activity in cells, 
    Chlamydia pneumoniae Consensus Conference, Carefree, AZ, June 13, 1998

  • Can we define breakpoints for intracellular infections ? 
    Pharmacokinetic/pharmacodynamic Interactions : concepts, controversies and challenges, International Society of Antiinfective Pharmacology/Paul Ehrlich Gesellschaft/2d European Congress of Chemotherapy, Hamburg, Germany, May 10, 1998