2023

• S. aureus internalisation and induction of antimicrobial tolerance
  33th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Copenhagen, Denmark- Session: Difficult-to-treat infections: the role of bacterial biofilm & persisters
  15 April 2023
  (PDF)
  
  
• Rationaliser l’usage des antibiotiques pour les préserver
  Symposium "teach the teacher": Défi écologique et soins de santé : Comment préparer les futurs soignants ?; Bruxelles, Belgique
  13 février 2023
  (PDF)
  

2022

• Tolerance of Staphylococcus aureus to antibiotics
  42ème Réunion Interdisciplinaire de Chimiothérapie Anti-Infectieuse [RICAI], Paris, France
  12 December 2022
  (PDF)
  
  
• New antibiotics in the pipeline against multidrug resistant Gram-negatives
  BVIKM-SBIMC symposium encollaboration avec la NVMM (Nederlandsevereniging voor MedischeMicrobiologie) et la NVII (Nederlandse Vereniging vanInternist-Infectiologen): "Changes in a borderless world", Bruges, Belgium
  8 November 2022
  (PDF)
  

2021

• Persistance intracellulaire de S. aureus : mécanismes sous–jacents et implications cliniques.
  5eme congrès du Centre de Référence des Infections Ostéo-Articulaires complexes [CRIOAC] (Lyon, France & on-line)
  21 October 2021
  (PDF)
  
  
• Optimising Antibiotic Treatment of Bone & Joint Infections : Pharmacokinetics of antibiotics in osteoarticular infections
  39th Annual meeting of the European Bone and Joint Infection Society (Ljubljana, Slovenia & on-line)
  8 October 2021
  (PDF)
  

• Recent developments in novel drug design and discovery: the current antibacterail drugs pipeline
  10th International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), Brussels, Belgium
  24 October 2020 (Virtual meeting)
  PDF (these slides were used to prepare a video [see next line], which was broadcasted to the registered participants)
  Video (mp4 file - 80 MBytes - cliclking the link will open video using the mp4-enabled video reader available on your computer - to download the file, right-click the link and select "save link as" [Windows]")
  
  
• Monitoring oxazolidinones
  Journées Nationales (françaises) d'Infectiologie (JNI), Poitires, France
  Session thématique (ST 11): Adapter la posologie des antibiotiques ?
  10 September 2020
  PDF (updated 4 Jan 2021) - The lecture was given in French but the slides are in English
  

2019 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• The Right Antibiotic: Potential Clinical Outcomes and the Hidden Risks of a Low Cost Therapy: a critical analysis of the generics
  Anti-infective Master Class - Live Webcast
  24 October 2019
  PDF (version updated on 29 and 30 October 2019)
  
  
• Intracellular models for antimicrobial R&D
  Global Antibiotic Research & Development Partnership (GARDP) Webinar
  9 July 2019
  PDF
  
  
• Epidemiology, risk factors, and comorbiditiesassociated with MRSA infections
  29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) - Industry integrated symposium: Walking a fine line to meet the clinical realities
  15 April 2019
  PDF
  
  
• Activity of drug combinations against staphylococcal biofilms
  29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) - Session: Thinking out of the box to beat biofilms
  14 April 2019
  PDF

2018 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• Therapeutic Drug Monitoring (TDM) of antibiotics
  5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) - European Union of Medical Specialists (UEMS) joint congress in Laboratory Medicine, Antalya, Turkey, 10-13 October 2018
  PDF
  
  
• Mechanims of resistance and susceptibility in Cystic Fibrosis (CF) pathogens
  41st European Cystic Fibrosis Conference, Belgrade, Serbia, 6-9 June 2018
  PDF
  
  
• What makes an antibiotic the right antibiotic ?
  Bayer China Anti-infective Summit, Shanghai, China, 12 May 2018
  English version: PDF - Chinese version: PDF
  
  
• Anti-infectives-biofilms interactions
  28ème Congrès National de la Société Tunisienne de Pathologie Infectieuse, Sousse, Tunisia, 27 April 2018
  PDF (English; see also an introductory presentation on biofilms in French: PDF [without video] - PDF [with video])
  
  
• Contribution of new antibiotics to current and future challenges of main Gram-positive infections
  Are Gram-positive infections still a major concern to patients and Healthcare system?
  European Congress of Clinical Microbiology and Infections (ECCMID) 2018 - Integrated symposium - Madrid, Spain, 23 April 2018
  PDF
  
  
• Skin and skin structures infections: various treatment approaches and pre-clinical profiles
  The evolving concept of bacterial infection in complicated patients
  European Congress of Clinical Microbiology and Infections (ECCMID) 2018 - Integrated symposium - Madrid, Spain, 21 April 2018
  PDF
  
  
• Update on PK/PD of antibiotics applied to critically ill patients: Focus on ß-lactams and vancomycin
  18th Vietnam Association of Critical Care Medicine, Emergency and Clinical Toxicology Annual Congress, Da Lat, Viet Nam, 12 April 2018
  PDF (English) - PDF (Vietnamese)
  
  
• Updating and optimizing carbapenem use in critically ill patients
  18th Vietnam Associatin of Critical Care Medicine, Emergency and Clinical Toxicology Annual Congress, Da Lat, Viet Nam, 12 April 2018
  PDF (Engllish)

2017 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• Discovery and exploitation of new targets for antibiotics: action on intracellular targets
  37ème Réunion Interdisciplinaire de Chimiothérapie Antiinfectieuse (RICAI), Paris, France, 19 December 2017
  PDF
  
  
• Looking into the future: How to adapt antibiotic use based on pharmacokinetics and pharmacodynamics
  Seminar of the Centre Hospitalo-Universitaire (CHU) of Charleroi, Lodelinsart, Belgium, 19 December 2017
  PDF
  
  
• Contribution of new antibiotics to today and tomorrow Gram-positive infections challenges
  ATHENA (Approaching THe sevErely iNfected pAtient) 2017 International Conference, Athens, Greece, 28-30 November 2017
  PDF
  
  
• Advancing mRSA Management: A New Force for the Clinicians
  Conferences given in Singapore, Singapore (29 November 2017) and in Kuala-Lumpur, Malaysia (30 November 2017)
  PDF
  
  
• Not All Fluoroquinolones ARE Equal
  Conferences given in Singapore, Singapore, 29 and 30 November 2017
  PDF
  
  
• New agents for MRSA: recently released or in the pipeline
  30th International Congress of Chemotherapy and Infection (Symposium #2: MRSA: global epidemiology and treatment), Taipei, Taiwan, 24-27 November 2017
  PDF
  
  
• Contribution of New and Future Antibiotics to Today and Tomorrow’s Gram-positive Infection Challenges
  MSD Global Infectious Diseases Forum, Madrid, Spain, 15-17 November 2017
  PDF
  
  
• Fluoroquinolones: Parenteral use
  6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
  PDF
  
  
• Branded vs. generic of antibiotics: Evidence-based approach
  6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
  PDF
  
  
• Three WHO Priority Pathogens: P. aeruginosa (critical), S. aureus (high), S. pneumoniae (medium)
  6th Anti-infectives in Middle East Experts Forum, Abu Dhabi, United Arab Emirates, 10-11 November 2017
  PDF
  
  
• New antimicrobial agents for the management ofMRSA acute bacterial skin and skin structure infections (ABSSSI): focus on tedizolid
  Lecture given in the Gulf States (Dubai, Kuwai, Abu Dhabi) - 24-27 October 2017
  PDF
  
  
• Pharmacokinetics, pharmacodynamics and toxicodynamics (how to boost efficacy, reduce toxicity, and mitigate resistance, with focus on aminoglycosides and oxazolidinones)
  Ribosomes & Antibiotics, University of Tartu, Tartu, Estonia, June 9-10, 2017
  PDF
  
  
• Improving antibiotic targeting in vivo
  40th European Cystic Fibrosis Conference (ECFC; Symposium S19: Next generation susceptibility testing - what works?), European Cystic Fibrosis Sociey (ECFS)? Sevilla, Spain, 7-10 June 2017
  PDF
  
  
• Modulating Intracellular Antimicrobial Activity
  ASM Microbe 2017 (Symposium: Pharmacodynamics in the intracellular space), New Orleans, LA, June 1-5,2017
  PDF
  
  
• The general Concepts of Pharmacokinetics
  ASM Microbe 2017 - Workshop, New Orleans, LA, June 1-5, 2017
  PDF
  
  
• Novel therapies and the role of early switch and early discharge protocols for management of MRSA infections.
  Integrated symposium: "Infections Due to MRSA: Walking a Fine Line to Meet Real World Expectations" - European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, 24 April 2017
  PDF
  
  
• New antibiotics: action on intracellular targets
  Symposium "Discovery and exploitation of new targets for antibiotics" - European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, 24 April 2017
  PDF (16:9)
  
  
• What do we know on PK/PD of ß-lactams ?
  Spring Symposium of the Belgian Society for Infectiology and Clinical Microbiology: "Parenteral antibiotics: from intensive to home dosing", Brussels, Belgium, 30 March 2017
  PDF
  
  
• Tolerance and resistance to antibiotics in Pseudomonas aeruginosa, or how do bacteria play with their environment
  Research Seminar, Institute of Technology, University of Tartu, Estonia, 8 March 2017
  PDF

2016 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• Moxifloxacin safety data review
  Fluoroquinolones and Respiratory Tract Infections, Beijing, China, 18th December 2016
  PDF
  
  
• Antibiotic resistance and global overview of the use of fluoroquinolones against S. pneumoniae
  The role of fluoroquinolones in managing S. pneumoniae, Singapore, 16th December 2016
  PDF
  
  
• Tedizolid: a novel treatment for Gram + infections and its potential role in clinical practice
  Full presentation [with backup slides] in Jeddah, Audi Arabia, November 26, 2016
  PDF (for shorter presentations made in Jeddah [27/11/2016] and in Riyadh [28/11/2016], click here.
  
  
• Antibiotics and biofilm: in vitro evidence and new clinical applications
  Séminaire de microbiologie et de maladies infectieuses, Université libre de Bruxelles (presented at the CHU St-Pierre, Brussels)
  PDF
  
  
• The bug: known and hidden challenges of infections with Staphylococcus aureus
  IDWeek 2016 (annual meeting of the Infectious Diseases Society of America), New Orleans, LA, October 26-31, 2016
  PDF (this presentation has been updated on November 3, 2016)
  
  
• Looking beyond clinical trials data ? An overview of new approaches in drug evaluation.
  1st Latin America Anti-infectives Forum, Cancun, Mexico, October 14-15, 2016
  PDF
  
  
• In vitro models for the study of the activity of anti-infective agents against biofilms
  Antimicrobial resistance in microbial biofilms and options for treatment, Conference of the European Society for Clinicla Microbiology and Infectious Diseases (ESCMID), Ghent, Belgium, 5-7 October 2016
  PDF (this presentation contains original material published on November 3, 2016)
  
  
• How active are antibiotics when directed towards bacteria hiding intracellularly? Do accumulation and subcellular disposition matter?
  3rd Global Microbiologists Annual Meeting, Portland, Oregon, United States, August 15-17, 2016
  PDF
  
  
• Is the expression of catalase by Staphylococcus aureus protective or detrimental to the survival of the bacteria when exposed to H2O2 in broth or after phagocytosis by monocytes? Are we disproving a dogma or misinterpreting data?
  3rd Global Microbiologists Annual Meeting, Portland, Oregon, United States, August 15-17, 2016
  PDF
  
  
• Are public campaigns effective to reduce antibiotic overconsumption ? Did we fail to provide what is needed by the general practitioner?
  3rd Global Microbiologists Annual Meeting, Portland, Oregon, United State, August 15-17, 2016 s
  PDF
  
  
• Anti-staphylococcal activity of antibiotics in biofilm and host cell
  Virulence and resistance in Staphylococcus aureus 2016: State of the art. ESCMID Postgraduate educational course, Lyon, France, 28 June-1 July 2016
  PDF
  
  
• Intracellular bacterial infections: why are antibiotics poorly efficient and can we do something about it ?
  Department of Chemistry and Biochemistry, University of Notre-Dame, Indiana, United States, 15 June 2016
  PDF
  
  
• Study of intracellular activity of antibiotics: significance for the clinical practice
  XVIII International Congress «Antimicrobial Therapy», Moscow, Russia, 25-27 May 2016
  PDF (English) - PDF (Russian)
  
  
• New forces in the managment of methicillin-resistant Staphylococcus aureus (MRSA)
  Anti-infective Seminar II: Hospital Infections, Singapore, 22 March 2016
  PDF
  
  
• Fluoroquinolones: are they all the same (or not) ?
  Anti-infective Seminar I: Community-acquired infections, Singapore, 22 March 2016
  PDF
  
  
• Pneumonia: not just a Gram-negative issue
  Vietnam workshop (held during the 10th Asia Respiratory Tract Forum), Taipei, Taiwan, 20 March 2016
  PDF
  
  
• What makes an antibiotic the right antibiotic (a story around respiratory tract infections) ?
  10th Asia Repiratory Tract Infections Forum, Taipei, Taiwan, 19-20 March 2016
  PDF
  

2015 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• New antibiotics: do we have them and how shall we pay for them ?
  Internal Seminar of the Cellular and Molecular Pharmacology group, Louvain Drug Research Institute, Brussels, 11 December 2015
  PDF
  
  
• “Generics of antibiotics:Evidence-based approach”
  Bayer Round-Table, Medellin, Colombia, 2 December 2015
  PDF
  
  
• The new antibiotics: useful improvement of our current armamentarium ... but can we pay for them?
  Universitad de Antioquia (Faculty of Medicine), Medellin, Colombia, 1 December 2015 (this presentation is focused on the US Regsitration and breakpoints)
  PDF
  
  
• The new antibiotics: useful improvement of our current armamentarium ... and can we pay for them?
  Séminaire du service des soins intensifs, Cliniques universitaires St-Luc, Bruxelles, Belgium, 26 November 2015 (this presentation is focused on the European Registration and breakpoints)
  PDF
  
  
• Colistin: news from an old drug
  Séminaire du service des soins intensifs, Cliniques universitaires St-Luc, Bruxelles, Belgium, 19 November 2015
  PDF
  
  
• Intracellular Activity of Antibiotics: the knowns, the uncertainties and the failures
  Pharmacokinetics UK (PK-UK), Chester, United Kigdom, 19 November 2015
  PDF
  
  
• Generics of antibiotics: an evidence-based approach
  Anti-Infective Bayer Middle East Forum, Dubai, UAE, 5th November 2015
  PDF
  
  
• MRSA in the Middle-East and Tedizolid (discovery & microbiology / pharmacokinetics / pharmacodynamics / pre-clinical safety)
  Anti-Infective Bayer Middle East Forum, Dubai, UAE, 5th November 2015
  PDF
  
  
• Antibiotic (accelerated) discovery and (more) rational use: a change in (accepted) paradigms based on economics ?
  DRIVE-AB 2015 General Assembly Meeting, Uppsala, Sweden, October 15-16, 2015 (keynote introductory lecture)
  PDF
  
  
• Colistin: what is new for an old antibiotic ?
  Groupe d'Etude de la Médecine (GLEM), Erasme Hospital, Brussels, Belgium, 14 October 2015
  PDF
  
  
• Looking into the future: routine TDM for beta-lactams in ICU ?
  14th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, Rotterdam, The Netherlands, 14 October 2015
  PDF
  
  
• The misuse of antibiotics in the management of respiratory infections and its consequences
  Master Class Vietnam-Indonesia, Geneva, Switzerland, 1 October 2015
  PDF
  
  
• The European road map against antimicrobial resistance... (a changing paradigm for drug discovery and development ?)
  2d International Conference on Polymyxins, La Jolla, CA, 22-24 September 2015
  PDF
  
  
• 24 years of ISAP: Achievements in the PK/PD field - A lecture In Memoriam Bill Craig
  ISAP Annual Meeting & post-ICAAC symposium, La Jolla, CA, September 21, 2015
  PDF
  
  
• Pumps (almost) everywhere: Impact on resistance and pharmacokinetics
  Groue local d'étude de la médecine (Soins Intensifs), Brussles, Belgium, 26 June 2015
  PDF
  
  
• Emerging antibiotic resistance
  26th Sigrid Jusélius International Symposium "Emerging Infections", Hanasaari Congress Center, Espoo–Helsinki, Finland, 7-10 June 2015
  PDF
  
  
• Treatment of infections in an era of resistance: the return of the old antibiotics… temocillin – nitrofurantoin – minocycline – trimethoprim-sulfamethoxazole
  Certificat interuniversitaire de formation en maladies infectieuses, Liège, Belgium, 4 June 2015 (some slides are in French)
  PDF
  
  
• Antibiotic research and development in the age of ‘superbugs’
  Lunch meeting at the European Parliament, Brussels, 27 May 1015
  PDF
  
  
• New antibacterial drugs: the drug pipeline for Gram-positive bacteria
  Gause Institute of New Antibiotics, Moscow, Russia, 22 May 2015
  PDF
  
  
• Drug pipeline for Gram-positive bacteria
  25th European Congress of Clinical Microbiology and Infectious Diseases ( Sympoisum: New antibacterail drugs), Copenhagen, Denmark, 25 April 2015
  PDF
  
  
• Resistance to antibiotics: the rise of efflux…
  Seminar of the Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium, 23 April 2015
  PDF
  
  
• Fluoroquinolones: are they all the same (or not) ?
  Lectures delivered at Kuala Lumpur and Pennang, Malaysia, 9-10 March 2015
  PDF
  
  
• Product Safety and Quality: An act of social and ethical responsibility (a discussion about generic antibiotics)
  - Strategies of antibiotic choice for in-patient treatment, Nha Trang, Vietnam, 12 March 2015 - PDF
  - 9th Asian Respiratory Tract Forum, Ho Vhi Minh City, Vietnam, 7-8 March 2015 - PDF
  
  
• Inhaled antimicrobial therapy: pharmacodynamics and risks for development of resistance
  6th International Symposium of KU Leuven “Pulmonary infections” - February 26-28, 2015, Leuven (Louvain), Belgium, 27 February 2015
  PDF
  
  
• Generics of antibiotics: Are you sure of what you get ?
  Seminar of the Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium, 8 January 2015
  PDF
  

2014 (by reverse chronological order; similar presentations are grouped and ordered as a function of the date of the last one)

• Antibiotic efflux pumps: from biology to clinical implications (and applications ?)
  Thematic week "Antibiotic Resistance", Université de Liège, Liége, Belgium, 4 December 2014
  PDF
  Survey of antibiotic efflux transporters in bacteria:
  up to 2002: Van Bambeke et al. J. Antimicrob. Chemother. 2003;51:1055-1065 [open access]
  up to 2008: Li & Nikado, Drugs 2009;69:1555-1623 [authors' copy]
  
  
• The major mechanisms of resistance to aminoglycosides, macrolides, and fluoroquinolones
  2014 ISF Stephen F. Lowry Colloquium - Intersection between Virulence and Antimicrobial Resistance in the ICU, Paris, France1-3 December 2014
  PDF
  
  
• Product Safety and Quality: An act of social and ethical responsibility (a discussion about generic antibiotics)
  Anti-Infective Bayer Middle East Forum, Dubai, United Arab Emirates, 7 November 2014
  PDF
  
  
• Community-acquired LRTIs in Middle East: an update from microbiology to pharmacology and toxicology
  Anti-Infective Bayer Middle East Forum, Dubai, United Arab Emirates, 7 November 2014
  PDF
  
  
• Optimisation of therapy in Gram-negative infections: TEMOCILLIN
  ESCMID (European Society of Clinical Microbiology and Infectious Diseases) conference on reviving old antibiotics, Vienna, Austria, 22-24 October 2014
  PDF
  
  
• Antibiotic Resistance Acquisition
  Good Bugs - Bad Bugs - XXX Rocourt Neonatology Meeting, Seraing, Belgium, 14 June 2014
  PDF
  
  
• Susceptibility trends in pneumonia pathogens and current prescribing
  24th European Congress of Clinical Microbiology and Infectious Diseases (Symposium: "Optimising diagnosis and appropriate antibiotic prescribing in pneumonia"), Barcelona, Spain, 12 May 2014
  PDF
  
  
• The (EU) authorities & their antibiotic development policy: a changing paradigm
  Bayer Anti-infective Therapies Symposium: Advancing Todays' Practice and Preparing The Future, Reet, Belgium, 15 May 2014
  PDF
  
  
• In vitro models for the study of antibiotic PK/PD in biofilms
  24th European Congress of Clinical Microbiology and Infectious Diseases (Symposium: "Exploring and treating biofilms"), Barcelona, Spain, 11 May 2014
  PDF
  
  
• New approaches to antibiotic therapy in Gram Gram-positive infections
  24th European Congress of Clinical Microbiology and Infectious Diseases (Integrated Symposium: "Perspectives on the evolution and dissemination of Gram-positive organisms: a global challenge"), Barcelona, Spain, 10 May 2014
  PDF
  
  
• Why monitoring beta-lactams on line ?
  Kick-off meeting of the MON4STRAT programme supported by the European Union (FP7), Liège, Belgium, 31 March-1 April 2014
  PDF

• Generics of antibiotics: are you sure of what you get (with a discussion about overconsumption and economy of low cost antibiotics) ?
  • Séminaire de médecine interne, CHU Mont-Godinne/Dinant, Yvoir, Belgium - 2 April 2014 (with updates of all links) - PDF
  • 8th Asian Respiratory Tract Forum, Jakarta, Indonesia - 29 March 2014 - PDF
  • Séminaire de microbiologie-maladies infectieuses, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium - 22 January 2014 - PDF
  • Séminaire interdisciplinaire de pathologie infectieuse, Grand Hôpital de Charleroi, Charleroi, Belgium - 11 February 2014 - PDF
    
    
• Ceftaroline: a new antibiotic for your patients ?
  Séminaire interdisciplinaire de pathologie infectieuse, Grand Hôpital de Charleroi, Charleroi, Belgium - 11 February 2014
  PDF

2013 (by reverse chronological order)

• In vitro pharmacodynamic models for the study of antibiotic activity against bacterial biofilms
  1st meeting of the Belgian Interdisciplinary Biofilm Research Group, Louvain-la-Neuve, Belgium, 20 December 2013
  PDF
  
  
• Antibiotic efflux pumps: from biology to clinical implications (and applications ?)
  Thematic week "Antibiotic Resistance", Université de Liège, Liege, Belgium, 4 December 2013
  PDF
  Survey of antibiotic efflux transporters in bacteria:
  up to 2002: Van Bambeke et al. J. Antimicrob. Chemother. 2003;51:1055-1065 [open access]
  up to 2008: Li & Nikado, Drugs 2009;69:1555-1623 [authors' copy]
  
  
• Guidelines & PK/PD for Pneumonia, Resistance (adults vs children) and "Last Year Review" in Respiratory Tract Infections
  INSPIRATION: Global Perspectives and Local Insights in Infection Management, Jeddah, Saudi Arabia, 15 November 2013
  "Guidelines & PK/PD" PDF // "Resistance" PDF // "Last Year" PDF
  
  
• Antibiotics case study: How can re-studying old drugs improve existing ones ?
  5th Annual Late Phase Leaders Forum, Brussels, Belgium, 12-14 November 2013
  PDF
  
  
• Generics of antibiotics: Are you sure of what you get ?
  Groupes de Gestion de l'Antibiothérapie (CHU Liège - CHU Citadelle), Liège, Belgium, 7 November 2013
  PDF
  
  
• Ceftaroline: a new antibiotic for your patients ?
  Groupes de Gestion de l'Antibiothérapie (CHU Liège - CHU Citadelle), Liège, Belgium, 7 November 2013
  PDF
  
  
• Guidelines in Community-acquired Pneumonia, Resistance (adults vs children) and "Last Year Review" in Respiratory Tract Infections
  INSPIRATION: Global Perspectives and Local Insights in Infection Management, Moscow, Russia, 12 October 2013
  "Guidelines" PDF (English) - PDF (Russian) // "Resistance" PDF (English) - PDF (Russian) // "Last Year" PDF (English) - PDF (Russian)
  
  
• Antibiotic resistance by efflux: from molecular aspects to cinical impact
  Seminar at the Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 16 September 2013
  PDF
  
  
• Approaches to Current and Future Treatment Options in Gram-positive Infections
  Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Denver, CO, 10 September 2013
  (Satellite meeting: Therapy for MRSA Infections in the Evolving Healthcare Environment)
  PDF
  
  
• Therapeutic options for MRSA: what next beyond vancomycin and linezolid ?
  3rd Shanghai International Congress on Clinical Microbiology and Antimicrobial Chemotherapy (SICCMAC), Shanghai, China, 23-25 August 2013
  PDF (English) - PDF (Chinese)
  
  
• Thoughts on generic product properties that might impact the clinical effect: what are the downsides ?
  Bayer-China Advisory Board, Beijing, China, 26 June 2013
  PDF (English) - PDF (Chinese)
  
  
• Treatment strategies and antibiotic pipeline for treatment of infections with resistant Gram-negative bacteria
  Antioticabeleidsgroep AZ St-Jan, Brugge, Belgium, 13 June 2013
  PDF
  
  
• Global Antibiotic Resistance in Respiratory Tract Infections
  • Vietnamese Master Class OM Pharma, Geneva, Switzerland, 3 June 2013
    PDF (English)
    
  • Chinese Master Class OM Pharma, Geneva, Switzerland, 2 May 2013
    PDF (English) - PDF (Chinese)
    
    
• Antibiotics in bone and joint infections
  Orthopaedica Belgica 2013 & Belgian Society of Clinical Microbiology and Infectious Diseases, Spa, Belgium, 25 April 2013
  PDF
  
  
• Prescribing guidelines in CAP: a global vision with a Russian perspective
  INSPIRATION: critical issues in infection management, Moscow, Russia, 6th April 2013
  PDF (English) - PDF (Russian)
  
  
• Pharmacological approaches to the discovery and optimized development of novel antibiotics
  National University of Vietnam - International University, Ho Chi Minh, Vietnam, 25 March 2013
  PDF
  
  
• Guidelines in Community-Acquired Pneumonia (CAP) and Chronic Obstructive Lung Disease (COPD): from diversity to logics
  7th Asian Respiratory Tract Infection Forum, Ho Chi Minh City, Vietnam, 24 March 2013
  PDF
  
  
• Understanding antibiotic PK/PD profiles to optimize patient outcomes
  7th Asian Respiratory Tract Infection Forum, Ho Chi Minh City, Vietnam, 23 March 2013
  PDF
  
  
• Moxifloxacin: PK/PD and safety profile
  Bayer Region EMEA Avelox Forum, Dubai, United Arab Emirates – 22 March 2013
  PDF
  
  
• Future design of (comparative) clinical trials or how to bring antibiotics to the bed side
  Ceftaroline Fosamil Speaker Summit (The Role of Ceftaroline in our Antibiotic Armamentarium), London, UK, 7 March 2013
  PDF
  
  
• From new bacterial targets to clinical applications
  WINP Tech 2012 (Workshop on Innovative and Pionnering Technologies), Kobe University, Kobe, Japan, 19 February 2013
  PDF

2012 (by reverse chronological order)

• Merging systems pharmacology with PK/PD analysis to enhance drug discovery: the case of novel antibiotics
  4th PK-PD Summit - Frankfurt, Germany, 27-29 November 2012
  PDF
  
  
• Comparative studies with antibiotics: Why should we change the rules?
  Late Phase Leaders Forum, Vienna, Austria, 8-10 October 2012
  PDF
  
  
• Guidelines in lower respiratory tract infections: from diversity to logics
  Commonwealth of Independent States (CIS) Consensus Meeting on Respiratory Tract Infections ("Inspiration" ), Kiev, Ukraine, 22-23 September 2012
  PDF (English) - PDF (Russian)
  
  
• Aminoglycosides: a new look at old but probably faithful antibiotics
  Invited Lecture - Department of Chemistry and Biochemistry, University of Notre-Dame, Notre Dame, Indiana, 17 September 2012
  PDF
  
  
• Hepatic Safety of Common Antibiotics
  52d Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA, 9-12 September 2012
  PDF
  
  
• Intra- and Extra-cellular Activities of Anti-Infective Agents
  52d Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA, 9-12 September 2012
  PDF
  
  
• Perspectives in antimicrobial agents
  European Society of Clinical Pharmacy, Leuven (Louvain), Belgium, 1 June 2012
  PDF
  
  
• EUCAST breakpoints
  Belgian Institute of Public Health (ISP/WIV), Brussels, Belgium, 31 May 2012
  PDF
  
  
• Intracellular bacteria and antibiotics: S. aureus, L. monocytogenes and P. aeruginosa
  Institut national de la recherche agronomique (INRA), Tours, France, 15 February 2012
  PDF
  
  
• Antibiotic efflux: from discovery to epidemiological, clinical, and veterinary impact
  Institut national de la recherche agronomique (INRA), Tours, France, 15 February 2012
  PDF
  
  
• EUCAST breakpoints
  13th Congress of the Lebanese Society for Infectious Diseases and Clinical Microbiology, Beirut, Lebanon, 2-4 February 2012
  PDF
  
  
• Guidelines in infectious diseases: from diversity to logics (a study about CAP guidelines)
  13th Congress of the Lebanese Society for Infectious Diseases and Clinical Microbiology, Beirut, Lebanon, 2-4 February 2012
  PDF
  

2011 (by reverse chronological order)

• Moxifloxacin safety data review
  8th Forschungswerkstatt Moxifloxacin 2011, Leverkusen, Germany, 18 November 2011
  PDF
  
  
• But where does the Pharmaceutical Industry go ... and Universities in all that business ?
  A3P Symposium Belgium, Spa, Belgium, 16 November 2011
  PDF
  
  
• Discovery of new antibiotics: Why and some approaches (with a short presentation of Belgium and of the Université catholique de Louvain)
  International University, Vietnam National University, Ho Chi Minh City, Vietnam, 10 October 2011
  PDF
  
  
• Colistin: from structure to clinical use via microbiology, PK/PD, and toxicology
  Bach Mai Hospital, Hanoi, Vietnam (within the context of a cooperative programme between Wallonie-Bruxelles International and the University of Pharmacy, Hanoi, Vietnam), 6 October 2011
  PDF
  
  
• Optimising treatment based on PK/PD principles
  Evolving Antibacterial Therapy - 30 years of clinical experience, 24-25 September, Istanbul, Turkey
  PDF
  
  
• Towards clinical Applications of PK-PD in specific situations
  51th Interscience Conference onf Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL. - ICAAC/ISAP Workshop - 16 September 2010
  PDF
  
  
• Guidelines in lower respiratory tract infections: from diversity to logics
  Latin-America consensus meeting on Respiratory Tract Infections ( "Inspiration" ), Rio-de-Janeiro, Brazil, 28-30 July 2011
  PDF
  
  
• Antibiotic resistance: are we heading for failures ?
  36th Annual Meeting of the International Urogynecological Association, Lisbon, Portugal, 29 June 2011
  Symposium "The guidelines offer more than antibiotics to manage recurrent urinary tract infections"
  PDF
  
  
• Towards rational international antibiotic breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)
  1st International & 12th Iranian Congress of Microbiology, Kermanshah, Iran, 23-26 May 2011
  PDF
  
  
• Hunting intracellular bacteria with antibiotics
  1st International & 12th Iranian Congress of Microbiology, Kermanshah, Iran, 23-26 May 2011
  PDF
  
  
• Improving usage by guidelines: a critical view
  21st European Congress of Chemotherapy and Infectious Diseases & 27th International Congress of Chemotherapy, Milan, Italy, 7-10 May 2011
  Symposium: Bridging the gap of innovation – what we all could do ?
  PDF
  
  
• Strategies to combat resistance: Focus on pharmacokinetics/ pharmacodynamics with applications to beta-lactams and a few words on colistin
  - Academy for Infection Management, India -- Mumbai (12-02) -- Chennai (13-02) -- Bangalore (14-02) -- Kolkata (15-02) -- Delhi (16-02) -- calculator (beta-lactams "concentration vs time" after IV bolus) (available soon)
  - International Critical care Congress 2001(CRITICARE 2001), Delhi 18 February 2011 - PDF (this set of slides contains also data on vancomycin)
  

2010 (by reverse chronological order)

• Respiratory fluoroquinolones: Benefit-Risk profiles
  Belgische Vereniging voor Pneumologie – Société belge de pneumologie, Antwerp, 27 November 2010
  PDF
  
  
• Towards clinical Applications of PK-PD in specific situations
  50th Interscience Conference onf Antimicrobial Agents and Chemotherapy (ICAAC), Boston, Mass. - ICAAC/ISAP Workshop - 11 September 2010
  PDF
  
  
• Hunting intracellular bacteria with antibiotics
  Invited Lecture - Department of Chemistry and Biochemistry, University of Notre-Dame, Notre Dame, Indiana, 9 September 2010
  PDF
  
  
• How do antibiotics play with multidrug transporters in eucaryotic cells ?
  462nd W.E. Heraeus Seminar, Jacobs University, Bremen, Germany, 9 July 2010
  PDF
  
  
• Antibiotic transporters in Pseudomonas aeruginosa and Streptococcus pneumoniae: impact on resistance and clinical significance
  (Introductory comment: why do we need but will have difficulties in getting new antibiotics)
  462nd W.E. Heraeus Seminar, Jacobs University, Bremen, Germany, 9 July 2010
  PDF
  
  
• Antibiotic efflux in procaryotic and eucaryotic cells: from molecular mechanisms to pharmacological consequences
  Institut National de la Recherche Agronomique, Toulouse, France, 21 May 2010
  PDF
  
  
• Impact of the antibiotic treatment on resistance of Pseudomonas aeruginosa in nosocomial pneumonia, or "Pseudomonas in Brussels in 2010"
  Séminaire de microbiologie et maladies infectieuses, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium, 24 March 2010
  PDF
  
  
• Intracellular Killing: Where’s the Bug? Where’s the Drug?
  Gordon Research Conference "New Antibacterial Discovery & Development", Galveston, TX, 18 March 2010
  PDF
  
  
• Update on new antibiotics in Belgium
  Seminar for Clinical pharmacists, Université catholique de Louvain & Cliniques universitaires St-Luc, Brussels, Belgium, 25 January 2010
  PDF

2009 (by reverse chronological order)

• Aminoglycosides: What have we learned about toxicity ?
  Infectious Diseases Society of America (IDSA) 47th Annual Meeting, Philadelphia, PA, 29 November 2009
  (Symposium # 153: Back to the Future: The Aminoglycosides are Here Again)
  PDF
  
  
• ABC transporters: from survival to resistance (or vice-versa)
  Colloque ABC franco-belge / ABC French-Belgian Colloquium, Paris, France, 14 October 2009
  PDF
  
  
• Iron metabolism and medical needs: a view from Academia
  Iron Therapy Master Class, Zürich, Switzerland, 13-15 October 2009
  PDF
  
  
• Efflux pump inhibitors to restore antibiotic efficacy
  ESCMID/FEMS Conference: "From Microbial Pathogenesis to the Discovery of Antivirulence Drugs", Les Diablerets, Switzerland, 4-8 October 2009
  PDF
  
  
• Administration of beta-lactams by continuous infusion: when, how, and for which molecules ?
  49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, CA (Meet-the-Experts – session 202. Optimization of Beta-Lactams: Continuous and Prolonged Infusions versus Standard Regimens) - 14 September 2009
  PDF
  
  
• Updates on treatment of Staphylococcus aureus / MRSA
  26th Annual Meeting of the Scandinavian Society of Antimicrobial Chemotherapy, Tromsoe, Norway, 5 September 2009
  PDF
  
  
• Safety of antibiotics used in respiratory tract infections: benefit-risk profile of moxifloxacin
  2009 Annual Meeting of the Finnish Society for Infectious Diseases (satellite symposium), Helsinki, Finland, 25 August 2009
  PDF
  
  
• Intracellular infection and activity of antibiotics: concepts and examples with Staphylococcus aureus and Listeria monocytogenes
  Lecture given at The Turku Center for Immunology, National Public Health Institute, Turku, Finland, 24 August 2009
  PDF
  
  
• Antibiotic selection in community-acquired pneumonia (CAP): appropriate benefit-risk profiles
  7th Forschungswerkstatt Moxifloxacin 2011, Leverkusen, Germany, 26 June 2011
  PDF
  
  
• Collateral effects of antibiotics:adverse effects and drug interactions
  26th International Congress of Chemotherapy and Infection (Meet the Experts session ME-41), Toronto, Ont., 20th June 2009
  PDF
  
  
• New antimicrobials
  27th Annual meeting of the European Society for Paediatric Infectious Diseases (ESPID), Brussels, Belgium, 12 June 2009
  PDF
  
  
• Adopting EUCAST breakpoints in countries currently on CLSI breakpoints and some personal thinking…
  19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki, Finland, 18 May 2009
  PDF
  
  
• Colistin pharmacokinetics/pharmacodynamics with an introduction and comments about reasonable uses
  19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki, Finland, 17 May 2009
  PDF
  
  
• Antibiotic transporters: Clinical Implications
  Gordon Reserach Conference "Efflux Transporters", Galveston, TX, 26 March 2009
  PDF
  
  
• Antibiotics for Community-acquired pneumonia (CAP): appropriate benefit-risk profiles
  - 5th Forum on Respiratory Tract Infections, Sitges (Barcelona), Spain, 5 February 2009  PDF
  - Italian medical educational meeting, Leverkusen, Germany, 6 March 2009  PDF
  - 7 Forschungswerkstatt Moxifloxacin, Leverkusen, Germany, 26 June 2009 PDF
  
  
• Doripenem vs meropenem: a summary of international and Belgian published data
  Brussels, Belgium, 2 February 2009
  PDF
  
  
• Deciphering the activity of antibiotics against intracellular Staphylococcus aureus with the help of PK/PD (pharmacokinetics/pharmacodynamics)
  Seminar held at the Institut für Medizinische Mikrobiologie, Universitätsklinikum Münster, Germany, 15 January 2009
  PDF

2008 (by reverse chronological order)

• Safety of moxifloxacin with special reference to the recent labelling change and benefit-risk ratio
  Lecture for Italian Infectious Diseases and Pulmonologists, Leverkusen, Germany, 2 december 2008
  PDF
  
  
• New developments in anti-Gram positive treatments
  Société belge d'infectiologie et de microbiologie clinique/Belgische Vereniging voor Infectiologie en Klnische Microbiologie, La Hulpe, 6 November 2008
  PDF
  
  
• Pharmacodynamics of antibiotics in cerebrospinal fluid (CSF): Principles and Consequences (factors predictive of efficacy)
  17ème Conférence de consensus en maladies infectieuses - Prise en charge des méningites bactériennes aiguës, Paris, 19 novembre 2008
  PDF (English version - pour une version française: cliquez ici)
  
  
• Toxicodynamics
  Symposium in honor of Prof. W.A. Craig, University of Madison, School of Medicine and Public Health, Madison, WI, October 29, 2008
  PDF
  
  
• How to target intracellular pathogens
  48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America(Symposium Pharmacokinetic/Pharmacodynamic - Factors in Treating Infection in Special Sites and/or Special Pathogens - session 53), Washington, DC, October 25, 2008
  PDF
  
  
• Aminoglycoside nephrotoxicity: a paradigm in toxicodynamic research
  48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America (Symposium Toxicodynamics - session 72), Washington, DC, October 26, 2008
  PDF
  
  
• Towards clinical Applications of PK-PD
  48th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America (Workshop), Washington, DC, October 24, 2008
  PDF
  
  
• Safety of moxifloxacin and its benefit-risk ratio in community setting
  Educational symposium at the occasion of the 2008 Annual Meeting of the European Respiratory Society, Berlin, Germany, October 6, 2008
  PDF
  
  
• From erythromycin to telithromycin: two bullets for one target ... what makes the difference ?
  2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
  PDF
  
  
• Chemotherapy and PK/PD of intracellular infections
  2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
  PDF
  
  
• Aminoglycoside nephrotoxicity: a paradigm in toxicodynamic research
  2nd World Conference on Magic Bullets (Ehrlich II), Nürnberg, Germany, October 3 - 5, 2008
  PDF
  
  
• Antibiotic transporters: from Discovery to Clinical Implications
  PhD's Day, Académie Bruxelles-Wallonie, Brussels, 20 May 2008
  PDF
  
  
• Activity of antibiotics against intracellular S. aureus
  European Congress of Clinical Microbiology and Infection (ECCMID), Barcelona, Spain - 21 April 2008
  PDF

2007 (by reverse chronological order)

• Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)
  Academy of Infection Management, Athens, Greece – 16 November 2007
  PDF
  
  
• Towards clinical Applications of PK-PD
  47th Interscience Conference on Antimicrobial Agents and Chemotherapy (Workshops), Chicago, IL, September 16th, 2007
  PDF
  
  
• Efflux as new challenge in antibacterial chemotherapy
  Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
  PDF
  
  
• Inhibitors of efflux pumps: the long journey from procaryotes to eukaryotes
  Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
  PDF
  
  
• Molecular bases for antibiotic resistance through efflux
  Transport across membranes: Multiple drug resistance, mechanisms and new tools. Summer School Jacobs University Bremen, July 8-14th, 2007
  PDF
  
  
• Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)and some personal thinking…
  Hospital Vesale, Montigny-le-Tilleul, Belgium - May 22d, 2007
  PDF
  version française (Le Roeulx [9/11] et Liège [11/11 ])
  Nederlandse versie (Hasselt [4/6], Antwerpen [11/6], Destelgem [18/6])
  
  
• Examining the interaction of drugs and membranes to improve selectivity
  Ehancing Screening Strategies with Cell-Based Assays, Informa-Life Sciences (Informa plc, London, UK), Munich, Germany - February 5-8th, 2007
  PDF
  
  
• Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST)and some personal thinking…
  Seminar for AstraZeneca, Destelbergen, Belgium, January 15, 2007
  PDF
  
  
• The bad and good uses of fluoroquinolones in urology
  Groupe local d'étude de la médecine (GLEM), Cliniques universitaires St-Luc, Brussels, Belgium - January 9, 2007
  PDF
  

2006 (by reverse chronological order)

• Are intracellular drug concentrations relevant for efficacy ? A discussion about accumulation, efflux and activity …
  2006 Joint Fall Meeting of the Nederlandse Vereniging voor Medische Microbiologie & Vereniging voor Infectie Ziekten, Amsterdam, The Netherlands, November 16, 2006
  PDF
  
  
• Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and some personal thinking…
  "Les midis de l'Infectiologie", Centre hospitalo-universitaire, Université de Liège, Belgium, November 14, 2006
  PDF
  
  
• Quinolones, macrolides, beta-lactams, glycopeptides ... and a few others against resistant S. aureus
  3d International Symposium on Gram-positive Infections, Niagara-on-the Lake, Ontario, October 9-11th, 2006
  PDF
  
  
• Pharmacokinetics of Old and New Glycopeptides
  46th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, San Francisco, CA, September 27, 2006
  PDF
  
  
• Pharmacodynamics of antibiotics as a means to improve and curb the emergence of resistance
  2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
  PDF
  
  
• New antistaphylococcal agents: hopes and limitations
  2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
  PDF
  
  
• Antibiotic restriction policies: are they applicable (and desirable) outside the western world ?
  2d International Symposium of the Jordanian Society of Pathology, Amman, Jordania, August 31, 2006
  PDF
  
  
• Pharmacodynamics of antibiotics …From what you already knew about " optimizing activity " ... to what you didn't dare to ask about emergence of resistance...
  Joint Spanish-Belgian Intensive Care meeting, Barcelona, Spain, April 22, 2006
  PDF
  
  
• Pharmacodynamics of antibiotics:Correlation between kinetics and activity
  4th Arab Symposium for Antimicrobial Agents / 16th National Tunisian Congress of Infectiology, Tunis, Tunisia, April 18th, 2006
  PDF
  
  
• Aminoglycosides: a new look at old but probably faithfull antibiotics
  Research Lecture for Pfizer Central Laboratories, Groton, Conn., April 12, 2006
  PDF
  
  
• Antibiotic combinations vs. monotherapy in critical care
  AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
  PDF
  
  
• PK/PD modeling of antibiotics: Clinical Implications
  AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
  PDF
  
  
• Pharmacodynamic indices in targeting therapy of critical infections
  AB-Biodisk Educational Workshop, Stockhom, April 5-6, 2003
  PDF
  
  
• PK/PD of antibiotics: from theory to applications in the real world...
  Joint Italian-Belgian Intensive Care meeting, Milan, Italy, March 18, 2006
  PDF
  
  
• Use of cell lines to study specific aspects related to bacterial infections and antibiotic transport
  International Worshop on Cellular Models in Drug Development, London, UK, February 15, 2006
  PDF
  
  
• Relationship between resistance, antibiotic policies, and clinical guidelines in the community: Government interventions on Antibiotic Policy in Belgium
  Libra Initiative European Summit, Brussels, Belgium, January 18, 2006
  PDF
  

• Models of antibiotic intracellular transport
  45th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, Washington, DC, December 19th, 2005
  PDF
  
  
• How to choose an antibiotic for respiratory tract infections in 2005
  Barcelona, Spain, November 24th, 2005
  PDF
  
  
• Antibiotic efflux pumps in eucaryotic cells: consequences for activity against intracellular bacteria
  Journée d'animation scientifique IFR 136 "Agents transmissibles et infectiologie - Mécanismes d’efflux et résistances aux agents thérapeutiques", Institut National de la Recherche Agronomique (INRA), Tours-Nouzilly, France, June 8th, 2005
  Web presentation - PDF
  

• The pharmacological and microbiological basis of PK/PD: Why did we have to invent PK/PD in the first place ?
  24th International Congress of Chemotherapy, Manila, Philippines, June 5, 2005
  Web presentation - PDF
  
  
• Towards Rational International Antibiotic Breakpoints: Actions from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) - A report to the Interntaional Scociety of Chemotherapy (ICC)
  24th International Congress of Chemotherapy, Manila, Philippines, June 4, 2005
  PDF
  
  
• Azalides revisited: why the single dose ?  The pharmacologist's answer
  24th International Congress of Chemotherapy, Manila, Philippines, June 4, 2005
  Web presentation - PDF
  

• Glycopeptides: how can a structural modification bring to a new life an old family of antibiotics ?
  Séminaire et Conférences du Département des Sciences Pharmaceutiques, Université catholique de Louvain, Brussels, Belgium, December 13th, 2004
  Web presentation - PDF
  
  
• Collaborations on antibiotics with the Rega Institute
  Rega Institute 50th Anniversary, Katholieke Universiteit Leuven, Louvain, Belgium, October 9th, 2004
  Web presentation - PDF
  
  
• Belgian Antibiotic campaigns (2000-2002)
  European Workshop on Antibiotic Campaigns, Brussels, Belgium, September 23-24, 2004
  Web presentation - PDF
  
  
• Intracellular antibiotics
  World Conference on Magic Bullets - Celebrating Paul Ehrlich's 150th birthday, Nuremberg, Germany, September 9-11th, 2004
  Web presentation - PDF
  
  
• Antibiotic efflux pumps in eucaryotic cells: consequences for activity against intracellular bacteria
  Cost B16 meeting (European Commission), Ghent, Belgium, May 28th, 2004
  Web presentation - PDF file
  
  
• Setting-up of a 24 h model to evaluate the activity of antibiotics against intracellular forms of S. aureus infection
  King Pharmaceuticals Workshop, Prague,Czech Republic, May 4th, 2004
  Web presentation - PDF file
  
  
• Vancomycin by continuous infusion ... Why and how ?
  GSK-Belgium satellite meeting - 14th European Congress of Chemotherapy, Prague, Czech Republic, May 3d, 2004
  Web presentation - PDF file
  
  
• MRSA treatments: does the future shine ?
  GSK-Belgium satellite meeting - 14th European Congress of Chemotherapy, Prague, Czech Republic, May 3d, 2004
  Web presentation - PDF file
  
  
• Nephrotoxicity of Aminoglycosides and Comparisons with Cis-Platinum
  American Association for Research in Otolaryngology, Annual Meeting - Presidential Symposium (Daytona Beach, FL),
  February 22, 2004
  Web presentation - PDF file
  

• Glycopeptides: from old Mississipi mud to new derivatives - a critical appraisal
  5th European Congress of Chemotherapy, Rhodos, Greece, October 20th, 2003
  
  
• Intracellular antibiotics and Listeria monocytogenes (State of the Art)
  5th European Congress of Chemotherapy, Rhodos, Greece, October 19th, 2003
  
  
• Efflux Mechanisms of  fluoroquinolones and beta-lactams
  MSD-closed meeting, September 14th, 2003, Chicago IL

2001

• Beta-lactams: from pharmacodynamics to applications in the real world...  (some slides are in Dutch and in French...)
  Belgian Intensive Care Study Group, September 11th, 2001, Cambridge, UK.

• A critical review of pharmacokinetics and toxicodynamics in preventing toxicity
  8th ISAP Symposium "Developments in Pharmacokinetics and Pharmacodynamics: optimizing efficacy and prevention of resistance", July 5th, 2001, Nijmegen, The Netherlands
  

• Intracellular antibiotic kinetics and dynamics : a reflexion of reality
  7th  International symposium on New Quinolones, 10-12 June 2001, Edinburgh, Scotland
  
  
• Pharmacokinetics and Pharmacodynamics in Drug Disvovery, Development and evaluation
  Conference given at the Therapeutics and Goods Administration (TGA), Australian Federal Ministry of Health, Canberra, ACT, Australia, April 9th, 2001
  
  
• Pharmacokinetic/ Pharmacodynamics in Antibiotic Evaluation, Clinical use, and Management of Resistance, ... or PK/PD like magic !
  4th Annual Conference of Infectious Diseases Pharmacotherapy, May 3d,  2001, Orlando, Fla.
  
  
• What is ISAP ? (a short description of the International Society of Antiinfective Pharmacology)
  4th Annual Conference of Infectious Diseases Pharmacotherapy, May 3d,  2001, Orlando, Fla.
  
  
• Pharmacokinetic/ Pharmacodynamics in Drug Discovery, Development and Evaluation.
  2d meeting of the Australian Society of Antimicrobials, Melbourne, Victoria, April 6th, 2001
  
  
• Intracellular Antibiotics : what does it (really) mean ?
  2d meeting of the Australian Society of Antimicrobials, Melbourne, Victoria, April 6th, 2001.
  
  
• Pharmacokinetics and pharmacodynamics for efficacy and prevention of resistance
  "Séminaire de Pathologie Infectieuse", Cliniques universitaires de l'UCL à Mont-Godinne, Yvoir, March 29th, 2001
  
  
• Pharmacokinetics / Pharmacodynamics as a mean to improve the medical prescription of antibiotics
  "Séminaire de l'Ecole de Pharmacie", Université catholique de Louvain, Brussels, Belgium, March 13, 2001
  
  
• Pharmacodynamics as a tool to improve the antiinfective therapy: from in vitro models to (some) large-scale clinical applications 
  Glaxo-SmithKline Belgian meeting on aminoglycoside monitoring and safety, Brussels, Belgium, January 17th, 2001
  

2000

• Isepamicin : discovery and evaluation of its renal safety 
  Monthly Infectiology Meeting of the Flemish-speaking Catholic University of Louvain (Maandelijke Infectiologie Vergaderingen van de KU-Leuven), Louvain (Leuven), Belgium, December 20th, 2000
  
  
• PK / PD (pharmacokinetics / pharmacodynamics) of antibiotics in clinical practice, 
  Bayer Antiinfective Symposium, New York, NY, December 8th, 2000
  
  
• Pharmacokinetics / Pharmacodynamics (PK/PD) like magic 
  Seminars of the Laboratory of Pharmacology of the University of Geneva (Séminaire du laboratoire de pharmacologie, Université de Genève), Geneva, Switzerland, December 5th, 2000
  
  
• Antibiotic transporters : biology, medical issues and drug development applications 
  Belgian Mucoviscidosis Symposium, Louvain (Leuven), Belgium, November 30th, 2000
  
  
• Pharmacokinetics and Pharmacodynamics of Antibiotics: a key to improved efficacy and prevention of resistance
  
  
• Cox-2 inhibitors: where are we ?
  Belgian Rheumatologists Training Group, Newcastle, UK, November 24th, 2000.
  
  
• Aminoglycosides and beta-lactams: from the work of Paul J. Claes to new recent developments, "Viering" (Emeritus Ceremony) of Professor P.J. Claes, Flemish-speaking Catholic University of Louvain (Katholieke Universiteit Leuven), Louvain (Leuven), Belgium, October 28th, 200) -- The first 5 and the last 2 slides are in Dutch.
  
  
• Teicoplanin and vancomycin: clinical indications and usefullness of drug monitoring,
  Seminar of Infectious Pathology (Séminaire de de pathologie infectieuse), Brussels, Belgium, October 26th, 2000
  
  
• New Goals, New Methods and New challenges in PK/PD of Antiinfective Agents
  7th ISAP International Symposium, Toronto, Ont. September 20th, 2000
  
  
• Cell culture methodologies for assesment of pharmacodynamics and toxicodynamics 
  Toxicodynamics of New Chemical entities (Tools for the Safer Design, Selection and Use of New Antibiotics), 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ont., September 20th, 2000
  
  
• Cellular and Tissular Accumulation of Drugs:  When is it Good and When is it Bad ?
  Antimicrobial resistance: inevitable or manageable ... ? (Satellite meeting to the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ont., September 17th, 2000)
  
  
• Dosing appropriately an antibiotic: does this this really matter ?
  Pharmacodynamics: Concepts and Applications (3d ISAP Educational Workshop), Toronto, Ont., September 16th, 2000
  
  
• The concentration-effect relationships for intracellular micro-organisms (drug trapping, ion pumps, intracellular MIC)
  Resistance and the use and misuse of antimicrobials, Alton Ochsner Medical Foundation Conferences, New Orleans, LA, June 26th, 2000
  
  
• New strategies to avoid development of resistance
   
• Macrolides: pharmacodynamics and pharmacokinetics.
  Macrolides revisited (closed workshop), Brussels, Belgium, June 16-17th, 2000
  
  
• Improving antiinfective therapy: a paradigm of fruitful cooperation between the E.U., Local Regulatory bodies, Academia and Industry ?
  "The cell factory", an EAG workshop, European Union, Brussels, Belgium, June 11th, 2000
   
  
• The concentration-effect relationships for intracellular micro-organisms (drug trapping, ion pumps, intracellular MIC) Education in pharmacokinetics and pharmacodynamics (2d ISAP Educational Workshop), Stockholm, Sweden, May 28th, 2000
  
  
• Intracellular anti-infectives: is it important for efficacy and do we need to care for toxicity?
  1st Swiss Advisory Board on the appropriate use of antibiotics (closed meeting), Bern, March 29, 2000
  
  
• Isepamicin: an old aminoglycoside in new clothes ? 
  Internal training and information seminar for GlaxoWellcome, Brussels, March 2000
  
  
• Pharmacokinetics / pharmacodynamics as a step towards a more effective therapy...  
  3d International Moxifloxacin Symposium, Monte-Carlo, Monaco, February 14th, 2000
  
  
• Intracellular pharmacodynamics: a Journey from Cell  biology to the Design of New Chemotherapeutic Agents 
  Advances in the Pharmacology of Antiinfective  Therapy (1st ISAP Educational International Symposium), Bangalore, India, January 21st, 2000.
  

before 2000

• Fluoroquinolones: structure versus activity and toxicity. 
  Société Belge d’Infectiologie et de Microbiologie Clinique/Belgische Vereniging voor Infectiologie en Klinische Microbiologie, St.-Niklaas, Belgium, December 11, 1999
  
  
• Fluoroquinolones : from structure to activity, 
  Internal training and education seminar for Bristol-Myers/Squibb, Brussels, Belgium, October 25, 1999
  
  
•  Aminoglycoside nephrotoxicity: from molecular pharmacology and pathology to some clinical applications (only part of ythe slides shown are available), 
  University of Cincinnati Medical Center (Division of Nephrology & Hypertension), Cincinnati, Ohio, October 9, 1999
  
  
• Intracellular infection : a journey from biology to therapy, 
  University of Cincinnati Medical Center (College of Pharmacy), Cincinnati, Ohio, October 8, 1999
  
  
• In vitro toxicodynamic models to accelerate drug selection and safety assessment,
  9th Symposium of the International Society for Anti-infective Pharmacology, Birmingham, United Kingdom, July 3, 1999
  
  
• Antibiotic use : is it time for a change ? My personal view, 
  Joint EMEA (European Agency for the Evaluation of Medicinal Products) / ISAP (International Society of Antiinfective Pharmacology), Uppsala, Sweden, June 10, 1999
  
  
• Can computer modelling predict the intracellular activity of antibiotics, 
  Symposium “Computer modelling of antibiotic response”, 9th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Berlin, Germany, March 24, 1999
  
  
• Intracellular anti-infectives: is it important for efficacy and do we need to care for toxicity?  
  1st workshop of the International Society of Antiinfective Pharmacology, Berlin, Germany, March 21,1999
  
  
• Pharmacokinetics and Pharmacodynamics in action : a view from the patient, 
  1st workshop of the International Society of Antiinfective Pharmacology, Berlin, Germany, March 21,1999
  
  
• Pharmacokinetic/ Pharmacodynamics in Drug Development and Evaluation 
  FDA / ISAP Workshop “Pharmacodynamics and the impact on antiinfective drug development”, Rockville, MD, March 1, 1999
  (Presidential address on behalf of the International Society of Antiinfective Pharmacology)
  
  
• Problems arising from the use of modern antibiotics  
  Opening lecture at the Annual Meeting of the Portuguese Society for Microbiology and Infectious Diseases, Coimbra, Portugal, February 25, 1999
  
  
• Antibiotic uptake in cells: do liposomes help ? 
  Symposium “"Pharmacological issues for antimicrobial Therapy using liposomes"
  38th Interscience Conference on Antimicrobial Agents and Chemotherapy, American Society of Microbiology, San Diego, CA, September 25, 1998
  
  
• Cultured cells models for the prospective assessment of anti-infective toxicity 
  Pharmacodynamics of Antiinfective Drugs as a Way to accelerate Drug Pre-clinical and Clinical Development, International Society of Antiinfective Pharmacology, San Diego, CA, September 23, 1998
  
  
• Defining the requirements for an intracellular antibiotic, 
  Pharmacodynamics of Antiinfective Drugs as a Way to accelerate Drug Pre-clinical and Clinical Development, International Society of Antiinfective Pharmacology, San Diego, CA, September 23, 1998
  
  
• Antibiotic distribution and activity in cells, 
  Chlamydia pneumoniae Consensus Conference, Carefree, AZ, June 13, 1998
  
  
• Can we define breakpoints for intracellular infections ? 
  Pharmacokinetic/pharmacodynamic Interactions : concepts, controversies and challenges, International Society of Antiinfective Pharmacology/Paul Ehrlich Gesellschaft/2d European Congress of Chemotherapy, Hamburg, Germany, May 10, 1998