Intracellular antibiotics and Listeria monocytogenes

5th European Congress of Chemotherapy, Rhodos, Greece, October 19th, 2003

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Intracellular antibiotics and Listeria monocytogenes

Why intracellular / intratissular antibiotics ?

Subcellular localization ?

Mechanisms of localisation and accumulation ...

Mechanisms of localisation and accumulation ...

Subcellular bioavailability of antibiotics ?

Subcellular bioavailability of antibiotics ?

Subcellular bioavailability of antibiotics ?

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Intracellular infection cycle of Listeria monocytogenes hly+

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But look at moxifloxacin (5h model) ...

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However, intracellular moxifloxacin is NOT more active intracellularly than extracellularly ...

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Author: Paul M. Tulkens

Email: tulkens@facm.ucl.ac.be

Home Page: http://www.md.ucl.ac.be/facm/facm-conferences.htm

Other information:
These slides are for information only. Do not make public use of them without autorization. Please, adress your request to <tulkens@facm.ucl.ac.be>

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