Université catholique de Louvain
Louvain Drug Research Institute > Cellular and Molecular Pharmacology
Scientific publications



"Was auch als Wahrheit oder Fabel
In tausend Büchern dir erscheint,
Das alles ist ein Turm zu Babel,
Wenn es die Liebe nicht vereint."
J.W. von Goethe


View of the private library of J.W. von Goethe, Goethe's House, Weimar, Germany

Photograph:
Toma Babovic,
LZW 3,
Edition Media dell'arte
(with permission)



In press | 2017 | 2016 | 2015  | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | before 2000

Key: New Latest addition in the corresponding section |  In French en français ... |  In Dutch in het Nederlands... | clinical pharmacy (see also Centre for Clinical Pharmacy)


In press or Advance Access (E-pub)
 (by reverse chronological order of acceptance)
  1. New Miranda Bastos AC, Vandecasteele SJ, Spinewine A, Tulkens PM, Van Bambeke F
    Temocillin dosing in haemodialysis patients based on population pharmacokinetics of total and unbound concentrations and Monte Carlo simulations
    Journal of Antimicrobial Chemotherapy - In press (accepted: 11 Feb 2018)
    Original paper - Journal impact factor (in 2016-2017): 5.071
    Unedited typecript (with supplementary material)

  2. Peyrusson F, Tulkens PM, Van Bambeke F
    Cellular pharmacokinetics and intracellular activity of gepotidacin against Staphylococcus aureus with different resistance phenotypes in models of cultured phagocytic cells
    Antimicrobial Agents and Chemotherapy - In press (accepted: 9 Jan 2018)
    Original paper - Journal impact factor (in 2016-2017): 4.302
    Unedited typescript

  3. Coenye T, Goeres D, Van Bambeke F, Bjarnsholt T
    Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?
    Clinical Microbiology and Infection - In press (accepted: 2 Jan 2018)
    Opinion paper - Journal impact factor (in 2016-2017): 5.292
    Unedited pre-print


  4. Milosevic TV, Payen VL, Sonveaux P, Muccioli GG, Tulkens PM, Van Bambeke F
    Mitochondrial alterations (inhibition of mitochondrial protein expression, oxidative metabolism and ultrastructure) induced by linezolid and tedizolid at clinically-relevant concentrations in cultured human HL-60 promyelocytes and THP-1 monocytes
    Antimicrobial Agents and Chemotherapy - In press (accepted: 10 Dec 2017)
    Original paper - Journal impact factor (in 2016-2017): 4.302
    Unedited typescript (with supplementary material)

Published papers and chapters of books
(by year and alphabetical order)

2017

  1. Anantharajah A, Buyck JM, Sundin C, Tulkens PM, Mingeot-Leclercq MP, Van Bambeke F
    Salicylidene acylhydrazides and hydroxyquinolines act as inhibitors of type three secretion systems in Pseudomonas aeruginosa by distinct mechanisms
    Antimicrobial Agents and Chemotherapy (2017) 61:e02566-16
    Original paper - Journal impact factor (in 2016): 4.415
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28396545
    Reprint [with Supplementary Material] (PDF) - - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.02566-16

  2. Buyck JM, Luyckx C, Muccioli GG, Krause KM, Nichols WW, Tulkens PM, Van Bambeke F
    Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa
    Journal of Antimicrobial Chemotherapy (2017) 72:1400-1409
    Original paper - Journal impact factor (in 2016): 4.916
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28137941
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dkw587 (may require a subscription)

  3. New Catteau L, Reichmann NT, Olson J, Pinho MG, Nizet V, Van Bambeke F, Quetin-Leclercq J
    Synergy between ursolic and oleanolic acids from Vitellaria paradoxa leaf extract and beta-lactams against methicillin-resistant Staphylococcus aureus: in Vitro and in Vivo Activity and underlying mechanisms
    Molecules (2017) 22:2245 (17 pages)
    Original paper - Journal impact factor: 2.861 (in 2016-2017)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=29258194
    Reprint [with Supplementary Material] (PDF) -
    Link to original document through DOI: 10.3390/molecules22122245


  4. Chalhoub H, Pletzer D, Weingart H, Braun Y, Tunney MM, Elborn JS, Rodriguez-Villalobos H, Plésiat P, Kahl BC, Denis O, Winterhalter M, Tulkens PM, Van Bambeke F
    Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic
    Scientific Reports (2017) 7:40208 (14 pages)
    Original paper - Journal impact factor: 5.228 (in 2016)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28091521
    Reprint [with Supplementary Material] (PDF) -
    Link to original document through DOI: 10.1038/srep40208


  5. New Defraine V, Verstraete L, Van Bambeke F, Anantharajah A, Townsend EM, Ramage G, Corbau R, Marchand A, Chaltin P, Fauvart M, Michiels J
    Antibacterial activity of 1-((2,4-dichlorophenethyl)amino)-3-phenoxypropan-2-ol against antibiotic-resistant strains of diverse bacterial pathogens, biofilms and in pre-clinical infection models
    Frontiers in Microbiology (2017) 8:2585 (10 pages)
    Original paper - Journal impact factor (in 2016-2017): 4.076
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=29312259
    Reprint (with Supplementary Materia) (PDF) -
    Link to original document through DOI: 10.3389/fmicb.2017.02585


  6. Delattre IK, Taccone FS, Jacobs F, Hites M, Dugernier T, Spapen H, Laterre PF, Wallemacq PE, Van Bambeke F, Tulkens PM
    Optimizing beta-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?
    Expert Review of Anti-Infective Therapy (2017) 15:677-688.
    Review and Expert Opinion - Journal impact factor (in 2016/2017): 3.139
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28571493
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1080/14787210.2017.1338139

  7. Dos Santos AG, Bayiha JC, Dufour G, Cataldo D, Evrard B, Silva LC, Deleu M, Mingeot-Leclercq MP
    Changes in membrane biophysical properties induced by the Budesonide/Hydroxypropyl-ß-cyclodextrin complex.
    Biochimica Biophysica Acta - Biomembranes (2017) 1859:1930-1940
    Original paper - Journal impact factor (in 2016): 3.498
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28642042
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.bbamem.2017.06.010 (may require a subscription)

  8. New Dos Santos AG, Marquês JT, Carreira AC, Castro IR, Viana AS, Mingeot-Leclercq MP, de Almeida RFM, Silva LC.
    The molecular mechanism of Nystatin action is dependent on the membrane biophysical properties and lipid composition.
    Physical Chemistry Chemical Physics (2017) 19:30078-30088
    Original paper - Journal impact factor (in 2016-2017): 4.123
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=29098221
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1039/c7cp05353c (may require a subscription)

  9. Houhoula D, Papaparaskevas J, Zatsou K, Nikolaras N, Malkawi HI, Mingeot-Leclercq MP, Konteles S, Koussisis S, Tsakris A, Charvalos E
    Magnetic nanoparticle-enhanced PCR for the detection and identification of Staphylococcus aureus and Salmonella enteritidis.
    New Microbiologica (2017) 40:165-169,
    Original paper - Journal impact factor (in 2016-2017): 1.568
    Asbtract
    Link to PubMed (US National Library of Medicine): PMID=28513808
    Reprint (PDF) -

  10. Le TB, Beaufay C, Nghiem DT, Mingeot-Leclercq MP, Quetin-Leclercq J
    In vitro anti-leishmanial activity of essential oils extracted from vietnamese plants
    Molecules (2017) 27;22:E1071 (12 pages)
    Original paper - Journal impact factor: 2.861
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28654013
    Reprint [with Supplementary Material] (PDF) -
    Link to original document through DOI: 10.3390/molecules22071071


  11. Leonard C, Conrard L, Guthmann M, Pollet H, Carquin M, Vermylen C, Gailly P, Van Der Smissen P, Mingeot-Leclercq MP, Tyteca D
    Contribution of plasma membrane lipid domains to red blood cell (re)shaping
    Scientific Reports (2017) 7:4264 (16 pages)
    Original paper - Journal impact factor: 5.228 (in 2016)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28655935
    Reprint [with Supplementary Material] (PDF) -
    Link to original document through DOI: 10.1038/s41598-017-04388-z


  12. Mustafa M-H, Khandekar S, Tunney MM, Elborn JS, Kahl BC, Denis O, Plésiat P, Traore H, Tulkens PM, Vanderbist F, Van Bambeke F
    Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients
    European Respiratory Journal (2017) 49:1601847 (13 printed pages)
    Original paper - Journal impact factor: 10.569 (in 2016/2017)
    Abstract
    Link to PubMed (US National Library of Medicine):
    PMID=28526799
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1183/13993003.01847-2016 (may require a subscription)

    The Journal published a commentary about this paper:
    Chalmers JD: Macrolide resistance in Pseudomonas aeruginosa: implications for practice.
    European Respiratory Journal (2017) 49:1700689 (3 printed pages)
    PDF (UCL only) - DOI: 10.1183/13993003.00689-2017 (may require a subscription)

  13. Oumar AA, Abdoulaye A, Maiga M, Sidibé Y, Cissoko Y, Konate I, Diarra M, Sangho F, Dembélé JP, Murphy RL, Tulkens PM, Dao S
    Adverse Drug Reactions to Antiretroviral Therapy (ART): Prospective Study in HIV Infected Adults in Sikasso (Mali)
    Journal of Pharmacovigilance (2017) 5:2 (6 pages)
    Original paper
    Reprint (PDF)
    Link to original document through DOI: 10.4172/2329-6887.1000228

  14. Tam VH, Chang KT, Zhou J, Ledesma KR, Phe K, Gao S, Van Bambeke F, Sánchez-Díaz AM, Zamorano L, Oliver A, Cantón R
    Determining beta-lactam exposure threshold to suppress resistance development in Gram-negative bacteria
    Journal of Antimicrobial Chemotherapy (2017) 72:1421-1428
    Original paper - Journal impact factor (in 2016): 4.916
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28158470
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dkx001 (may require a subscription)


2016

  1. Anantharajah A, Faure E, Buyck JM, Sundin C, Lindmark T, Mecsas J, Yahr TL, Tulkens PM, Mingeot-Leclercq M-P, Guery B, Van Bambeke F
    Inhibition of the injectisome and flagellar type III secretion systems by INP1855 impairs Pseudomonas aeruginosa pathogenicity and inflammasome activation
    Journal of Infectious Diseases (2016) 214:1105-1116
    Original paper - Journal impact factor (in 2015): 6.344
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27412581
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/infdis/jiw295 (may require a subscription)

  2. Anantharajah A, Mingeot-Leclercq MP, Van Bambeke F
    Targeting Type Three Secretion System in Pseudomonas aeruginosa
    Trends in Pharmacological Sciences (2016) 37:734-749
    Review - Journal impact factor (in 2015): 11.539
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27344210
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.tips.2016.05.011 (may require a subscription)

  3. Buyck JM, Lemaire S, Seral C, Anantharajah A, Peyrusson F, Tulkens PM, Van Bambeke F
    In vitro Models for the Study of the Intracellular Activity of Antibiotics
    In “Bacterial Persistence”, Molecular Biology Laboratory Protocols Series, J. Michiels and M. Fauvart, editors, 2016, p 147-157
    Humana Press (Springer), ISBN 978-1-4939-2853-8 ; ISBN 978-1-4939-2854-5 (ebook)
    Chapter of book
    Reprint (PDF) -
    UCL only - Copyright owned by the publisher
    Link to full book through DOI: 10.1007/978-1-4939-2854-5 (may require a subscription)

  4. Ceyssens PJ, Van Bambeke F, Mattheus W, Bertrand S, Fux F, Van Bossuyt E, Damée S, Nyssen H-J, De Craeye S, Verhaegen J, The Belgian Streptococcus pneumoniae Study Group, Tulkens PM, Vanhoof R
    Molecular analysis of rising fluoroquinolone resistance in Belgian non-invasive Streptococcus pneumoniae isolates (1995-2014)
    PLoS One (Public Library of Science) (2016) 11:e0154816 (17 pages)
    Original paper - Journal impact factor: 3.234 (in 2015)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27227336
    Reprint [with Supplementary Material] (PDF) -
    Link to original document through DOI: 10.1371/journal.pone.0154816


  5. Chalhoub H, Sáenz Y, Rodriguez-Villalobos H, Denis O, Kahl BC, Tulkens PM, Van Bambeke F
    High-level resistance to meropenem in clinical isolates of Pseudomonas aeruginosa in the absence of carbapenemases: role of active efflux and porin alterations
    International Journal of Antimicrobial Agents (2016) 48:740-743. doi: 10.1016/j.ijantimicag.2016.09.012.
    Original paper - Journal impact factor (in 2015) : 4.097
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=28128097
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.ijantimicag.2016.09.012 (may require a subscription)

  6. Denamur S, Boland L, Beyaert M, Verstraeten SL, Fillet M, Tulkens PM, Bontemps F, Mingeot-Leclercq MP
    Subcellular mechanisms involved in apoptosis induced by aminoglycoside antibiotics: Insights on p53, proteasome and endoplasmic reticulum
    Toxicology and Applied Pharmacology (2016) 309:24-36.
    Original paper - Journal impact factor: 3.847 (in 2015)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27568863
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.taap.2016.08.020
    (may require a subscription)

  7. Lorent JH, Léonard C, Abouzi M, Akabi F, Quetin-Leclercq J, Mingeot-Leclercq MP
    Alpha-hederin induces apoptosis, membrane permeabilization and morphologic changes in two cancer cell lines through a cholesterol-dependent mechanism
    Planta Medica (2016) 82:1532-1539.
    Original paper - Journal impact factor (in 2015): 1.990
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27574896
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1055/s-0042-114780
    (may require a subscription)

  8. Mingeot-Leclercq MP, Décout JL
    Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal
    of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

    MedChemComm (Medicinal Chemical Communications) (2016) 7:586-611
    Review - Journal impact factor; 2.495 (in 2015)
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1039/c5md00503e (may require a subscription)

  9. New Mustafa MH, Chalhoub H, Denis O, Deplano A, Vergison A, Rodriguez-Villalobos H, Tunney MM, Elborn JS, Kahl BC, Traore H, Vanderbist F, Tulkens PM, Van Bambeke F
    Antimicrobial susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients through Northern Europe
    Antimicrobial Agents and Chemotherapy (2016) 60:6735-6741
    Original paper - Journal impact factor (in 2015) : 4.415
    Abstract
    Link to PubMed (US National Library of Medicine): PMID= 27572406
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.01046-16
    (may require a subscription)

  10. Riou M, Avrain L, Carbonnelle S, El Garch F, Pirnay JP, De Vos D, Plésiat P, Tulkens PM, Van Bambeke F
    Increase of efflux-mediated resistance in Pseudomonas aeruginosa during antibiotic treatment in patients suffering from nosocomial pneumonia

    International Journal of Antimicrobial Agents (2016) 47:77–83
    Original paper - Journal impact factor: 4.296 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26691019
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.ijantimicag.2015.11.004 (may require a subscription)

  11. Sautrey G, El Khoury M, Dos Giros A, Zimmermann L, Deleu M, Lins L, Decout JL, Mingeot-Leclercq MP.
    Negatively-charged lipids as potential target for new amphiphilic aminoglycoside antibiotics: a biophysical study
    Journal of Biological Chemistry (2016) 291:13864-13874
    Original paper - Journal impact factor (in 2015): 4.573
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27189936
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1074/jbc.M115.665364 (may require a subscription)

  12. Siala W, Kucharíková S, Braem A, Vleugels J, Tulkens PM, Mingeot-Leclercq MP, Van Dijck P, Van Bambeke F
    The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase
    Nature Communications (2016) 7:13286
    Original paper - Journal impact factor (in 2015): 11.329
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=27808087
    Reprint [with supplementary material] (PDF)
    Link to original document through DOI: 10.1038/ncomms13286

  13. Siala W, Van Bambeke F, Taresco V, Piozzi A, Francolini I
    Synergistic activity between an antimicrobial polyacrylamide and daptomycin vs. Staphylococcus aureus biofilm
    Pathogens and Disease (2016) 74:ftw042 (8 pages)
    Original paper - Journal impact factor (in 2015): 2.403
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27154750
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/femspd/ftw042 (may require a subscription)

  14. Van Bambeke F, Tulkens PM
    Colistin and a new paradigm in drug development
    Clinical Infectious Diseases (2016) 62:559-560.
    Comment on "Updated United States and European dose recommendations for intravenous colistin: How do they perform?" by Nation et al. Clin Infect Dis 2016; 62:552–8.
    Clinical Infectious Diseases (2016) 62:559-560
    Invited Comment - Journal impact factor: 8.886 (in 2014)
    Link to PubMed (US National Library of Medicine): PMID= 26607423
    Reprint (PDF) -
    UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/cid/civ968

  15. Van Bambeke F, Tulkens PM.
    The role of solithromycin in the management of bacterial community-acquired pneumonia
    Expert Review on Anti-infective Therapy (2016) 14:311-324
    Review paper - Journal impact factor (in 2015): 3.461
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26848612
    Reprint (PDF) -
    UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1586/14787210.2016.1138857


  16. Vandevelde NM, Tulkens PM, Van Bambeke F
    Modulating antibiotic activity towards respiratory bacterial pathogens by comedications: a multi-target approach
    Drug Discovery Today (2016) 21:1114-1129
    Keynote Review - Journal impact factor (in 2015): 6.691
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27094105
    Reprint (PDF) -
    UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.drudis.2016.04.001

  17. New Zimmermann L, Das I, Désiré J, Sautrey G, Barros R S V, El Khoury M, Mingeot-Leclercq MP, Decout JL
    New broad-spectrum antibacterial amphiphilic aminoglycosides active against resistant bacteria: from neamine derivatives to smaller neosamine analogues
    Journal of Medicinal Chemistry (2016) 59:9350-9369
    Original paper - Journal impact factor (in 2015): 5.589

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=27690420
    Reprint [with supplementary material] (PDF) -
    UCL only - Copyright owned by the publisher
    SMILES in CSV format [right-click to save as .csv file]
    Link to original document through DOI: 10.1021/acs.jmedchem.6b00818


2015

  1. Anantharajah A., Buyck J.M., Faure E., Glupczynski Y., Rodriguez-Villalobos H., De Vos D., Pirnay J-P., Bilocq F. Guery B., Tulkens P.M., Mingeot-Leclercq M-P., Van Bambeke F.
    Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1-beta secretion in a model of human THP-1 monocytes
    FEMS Pathogens and Disease (2015) 73:ftv049.
    Original paper - Journal impact factor: 2.403 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID= 26203053
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/femspd/ftv049 (may require a subscription)


  2. Buyck JM, Peyrusson F, Tulkens PM, Van Bambeke F
    RX-P873, a novel protein synthesis inhibitor, accumulates in human THP-1 monocytes and is active against intracellular infections by Gram-positive
    (Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa) bacteria

    Antimicrobial Agents and Chemotherapy (2015) 59:4750-4758
    Original paper - Journal impact factor: 4.476 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26014952
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.00428-15 (may require a subscription)


  3. Buyck JM, Tulkens PM, Van Bambeke F
    Activity of antibiotic combinations towards resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes.
    Antimicrobial Agents and Chemotherapy (2015) 59:258-268
    Original paper - Journal impact factor: 4.476 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=25348528
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.04011-14 (may require a subscription)

  4. Catteau L, Van Bambeke F, Quetin-Leclercq J
    Preliminary evidences of the direct and indirect antimicrobial activity of 12 plants used in traditional medicine in Africa
    Phytochemistry Reviews (2015) 14:975–991
    Original paper - Journal impact factor: 2.407 (in 2014)
    Abstract
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1007/s11101-015-9437-x (may require a subscription)

  5. Chalhoub H, Tunney M, Elborn JS, Vergison A, Denis O, Plésiat P, Kahl BC, Van Bambeke F, Tulkens PM
    Avibactam confers susceptibility to a large proportion of ceftazidime-resistant Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients
    Journal of Antimicrobial Chemotherapy (2015) 70:1596-8
    Original paper (Research Letter) - Journal impact factor: 5.313 (in 2014)
    No abstract available
    Link to PubMed (US National Library of Medicine): PMID=25587996
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dku551 (may require a subscription)

  6. In French Claeys C, Dufrasne M, De Vriese C, Nève J, Tulkens PM, Spinewine A
    Transmission d’information au pharmacien d’officine après hospitalisation du patient : élaboration d’une feuille de transfert, évaluation prospective de son effet et enquête sur les besoins d’information des pharmaciens
    Journal de Pharmacie de Belgique (2015) 97:42-54
    Original paper
    Abstract (in English and in French)
    Link to PubMed (US National Library of Medicine): PMID=26571796 (English)
    Reprint (PDF) (French) - UCL only - Copyright owned by the publisher

  7. In Dutch Claeys C, Dufrasne M, De Vriese C, Nève J, Tulkens PM, Spinewine A
    Informatieoverdracht naar de officina-apotheker na ziekenhuisopname: ontwikkeling van een transferblad, prospectieve evaluatie van het effectervan en onderzoek naar de informatienoden van apothekers
    Farmaceutisch Tijdschrift voor België (2015) 95:42-54
    Original paper (Dutch version of the previous paper)
    Abstract (in English and in Dutch)
    Link to PubMed (US National Library of Medicine): PMID=26571796 (English)
    Reprint (PDF) (Dutch) - UCL only - Copyright owned by the publisher

  8. Flanagan S, McKee EE, Das D, Tulkens PM, Hosako H, Fiedler-Kelly J, Passarell J, Radovsky A, Prokocimer P
    Evaluation of the potential of tedizolid and linezolid to affect mitochondrial function using nonclinical and pharmacokinetic assessments
    Antimicrobial Agents and Chemotherapy (2015) 59:178-185
    Original paper - Journal impact factor: 4.476 (in 2014)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=25331703
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.03684-14 (may require a subscription

  9. Frippiat F, Musuamba PT, Seidel L, Albert A, Denooz R, Charlier C, Van Bambeke F, Wallemacq P, Descy J, Lambermont B, Layios N, Damas P, Moutschen M
    Modelled target attainment after meropenem infusion in patients with severe nosocomial pneumonia: the PROMESSE study
    Journal of Antimicrobial Chemotherapy (2015) 70:207-216
    Original paper - Journal impact factor: 5.313 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=25216821
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dku354 (may require a subscription)

  10. Laterre PF, Wittebole X, Van de Velde S, Muller AE, Mouton JW, Carryn S, Tulkens PM, Dugernier T
    Temocillin 6 g daily in critically-ill patients: continuous infusion versus thrice daily administration
    Journal of Antimicrobial Chemotherapy (2015) 70:891–898
    Original paper - Journal impact factor: 5.313 (in 2014)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=25433006
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dku465/ (may require a subscription)

  11. Ngougni Pokem P, Miranda Bastos AC, Tulkens PM, Wallemacq P, Van Bambeke F, Capron A
    Validation of a HPLC-MS/MS assay for the determination of total and unbound concentration of temocillin in human serum
    Clinical Biochemistry (2015) 48:542–545
    Original paper - Journal impact factor: 2.275 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=25712752
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.clinbiochem.2015.02.006 (may require a subscription)

  12. Oumar AA, Maiga M, Dembele JP, Djibril N, Sangho F, Konate I, Kone Y , Guida L, Tulkens PM, Dao S
    Adverse neurological events due to antiretroviral therapy in Mali
    International Journal of Research in Pharmacology & Pharmacotherapeutics (2015) 4:455-459
    Original paper - No impact factor
    Abstract
    Reprint (PDF) Open access

  13. Peyrusson F, Butler D, Tulkens PM, Van Bambeke F
    Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes. Studies with human THP-1 monocytes and J774 murine macrophages
    Antimicrobial Agents and Chemotherapy (2015) 59:5747-5760
    Original paper - Journal impact factor: 4.476 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26169402
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.00827-15 (may require a subscription)


  14. Theuretzbacher U, Ambrose PG, MacGowan AP, Andes DR, Sörgel F, Derendorf H, Mouton JW, Drusano GL, Tulkens PM, Dudley MN, Cars O, Nation RL
    In memoriam William A. Craig
    Antimicrobial Agents and Chemotherapy (2015) 59:2971
    Editorial - Journal impact factor: Impact factor: 4.476 (in 2014)
    Link to PubMed (US National Library of Medicine): PMID=25896702
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.00849-15 (may require a subscription)

  15. Theuretzbacher U, Van Bambeke F, Cantón R, Giske GC, Mouton JW, Nation RL, Paul M, Turnidge JD, Kahlmeter G
    Reviving old antibiotics
    Journal of Antimicrobial Chemotherapy (2015) 70:2177–2181
    Leading article - Journal impact factor: 5.313 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26063727
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dkv157 (may require a subscription)

  16. Van Bambeke F
    Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: Evaluation of its pharmacology, pharmacokinetics, pharmacodynamics, and clinical efficacy
    Future Microbiology: Drug Evaluation review (2015) 10:1111–1123
    Review - Journal impact factor: Impact factor: 4.275 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26119479
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.2217/FMB.15.39 (may require a subscription)

  17. Van Bambeke F
    Lipoglycopeptide antibacterial agents in Gram-positive infections: A comparative review
    Drugs (2015) 75:2073-2095
    Review paper
    - Journal impact factor: 4.343 (in 2014)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=26603874
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1007/s40265-015-0505-8 (may require a subscription)

  18. Vandecasteele SJ, Miranda Bastos AC, Capron A, Spinewine A, Tulkens PM, Van Bambeke F
    Thrice weekly temocillin administered after each dialysis session is appropriate for the treatment of serious Gram-negative infections in haemodialysis patients.
    International Journal of Antimicrobial Agents (2015) 46:660-665
    Original paper - Journal impact factor: 4.296 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=26603304
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.ijantimicag.2015.09.005 (may require a subscription)

  19. Vandevelde NM, Tulkens PM, Muccioli GG, Van Bambeke F
    Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of S. pneumoniae naive and induced biofilms
    Journal of Antimicrobial Chemotherapy (2015) 70:1713-1726
    Original paper - Journal impact factor: 5.313 (in 2014)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=25712316
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dkv032 (may require a subscription)

2014

  1. Das D, Tulkens PM, Mehra P, Fang E, Prokocimer P
    Tedizolid phosphate for the management of acute bacterial skin and skin structure infections: Safety summary
    Clinical Infectious Diseases (2014) 58 (Suppl 1):S51–S57
    Original paper - Journal impact factor: 9.416
    (in 2013)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=24343833

    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/cid/cit618 (may require a subscription)

  2. Imöhl M, Reinert RR, Tulkens PM, van der Linden M
    Penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effect on susceptibility categorisation in Germany (1997-2013)
    European Journal of Clinical Microbiololgy & Infectious Diseases (2014) 33:2035–2040
    Original paper - Journal impact factor: 2.544 (in 2013)
    Abstract
    Link to Pubmed (US National Library of Medicine): PMID=24930041
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1007/s10096-014-2174-z (may require a subscription)

  3. Lemaire S, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F
    Study of macrophage functions in murine J774 cells and human activated THP-1 cells exposed to oritavancin, a lipoglycopeptide with high cellular accumulation
    Antimicro
    bial Agents and Chemotherapy (2014) 58:2059-2066
    Original paper - Journal impact factor: 4.451 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 24449768
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.02475-13 (may require a subscription)

  4. Lorent J, Lins L, Domenech O, Quetin-Leclercq J, Brasseur R, Mingeot-Leclercq MP
    Domain formation and permeabilization induced by the saponin alpha-Hederin and its aglycone hederagenin in a cholesterol-containing bilayer
    Langmuir (2014) 30:4556-4569
    Original paper - Journal impact factor: 4.384 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 24690040
    Reprint (PDF) - UCL only - Copyright owned by the publisher - video
    Link to original document through DOI: 10.1021/la4049902 (may require a subscription)

  5. Lorent JH, Quetin-Leclercq J, Mingeot-Leclercq MP
    The amphiphilic nature of saponins and their effects on artificial and biological membranes and potential consequences for red blood and cancer cells
    Organic & Biomolecular Chemistry (2014) 12:8803-8822
    Review - Journal impact factor: 3.487 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID=25295776
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1039/c4ob01652a (may require a subscription)

  6. Marquez B, Pourcelle V, Vallet CM, Mingeot-Leclercq MP, Tulkens PM, Marchand-Bruynaert J, Van Bambeke F
    Pharmacological characterization of 7-(4-(piperazin-1-yl)) ciprofloxacin derivatives: antibacterial activity, cellular accumulation, susceptibility to efflux transporters, and intracellular activity
    Pharmaceutical Research (2014) 31:1290–1301
    Original paper - Journal impact factor: 3.952 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 24306327
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1007/s11095-013-1250-x (may require a subscription)

  7. Miranda Bastos AC, Vandecasteele SJ, Tulkens PM, Spinewine A, Van Bambeke F
    Development and validation of a High Performance Liquid Chromatography Assay for the Determination of Temocillin in Serum of Haemodialysis Patients
    Journal of Pharmaceutical and Biomedical Analysis (2014) 90:192–197
    Original paper - Journal impact factor: 2.829 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 24389461
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.jpba.2013.12.002 (may require a subscription)

  8. Sautrey G, Zimmermann L, Deleu M, Delbar A, Souza Machado L, Jeannot K, Van Bambeke F, Buyck JM, Decout J-L, Mingeot-Leclercq M-P
    New amphiphilic neamine derivatives active against resistant Pseudomonas aeruginosa and their interactions with lipopolysaccharides
    Antmicrobial Agents and Chemotherapy (2014) 58:4420-4430
    Original paper - Journal impact factor: 4.451 (in 2013)
    Abstract
    Link to Pubmed (US National Library of Medicine): PMID= 24867965
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.02536-13 (may require a subscription)

  9. Siala W, Mingeot-Leclercq M-P, Tulkens PM, Hallin M, Denis O,Van Bambeke F
    Antibiotic activity against biofilms from Staphylococcus aureus clinical isolates: factors determining the activity of the investigational fluoroquinolone delafloxacin in comparison with daptomycin and vancomycin
    Antimicrobial Agents and Chemotherapy (2014) 58:6385-6398
    Original paper - Journal impact factor: 4.451 (in 2013)
    Abstract
    Link to Pubmed (US National Library of Medicine): PMID=25114142
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.03482-14 (may require a subscription)

  10. Van Bambeke F
    Macrolides and Ketolides
    In:
    Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics (Chapter 11), A. Vinks, H Derendorf & JW Mouton, editors, 2014, p 257-278
    Springer, ISBN 978-0-387-75612-7 - ISBN 978-0-387-75613-4 (eBook)
    Chapter of book
    Reprint (PDF) -
    UCL only - Copyright owned by the publisher
    Link to full book through DOI: 10.1007/978-0-387-75613-4

  11. Van Bambeke F
    Renaissance of antibiotics against difficult infections: Focus on oritavancin and new ketolides and quinolones
    Annals of Medicine (2014) 46(7):512-29.
    Review - Journal impact factor: 4.733 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 25058176
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.3109/07853890.2014.935.470 (may require a subscription)


  12. Vandevelde NM, Tulkens PM, Van Bambeke F
    Antibiotic activity against naive and induced Streptococcus pneumoniae biofilms in an in vitro pharmacodynamic model
    Antimicrobial Agents and Chemotherapy (2014) 58:1348-1358
    Original paper - Journal impact factor: 4.451 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 24342635
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1128/AAC.01858-13 (may require a subscription)

  13. Vandevelde NM, Tulkens PM, Diaz Iglesias Y, Verhaegen J, Rodriguez-Villalobos H, Philippart I, Cadrobbi J, Coppens N, Boel A, Van Vaerenbergh K, Francart H, Vanhoof R, Liistro G, Jordens P, d’Odemont J-P, Valcke Y, Verschuren F, Van Bambeke F
    Characterization of a collection of Streptococcus pneumoniae isolates from patients suffering from acute exacerbations of chronic bronchitis: in vitro susceptibility to antibiotics and biofilm formation in relation with antibiotic efflux and serotypes/serogroups.
    International Journal of Antimicrobial Agents (2014) 44:209–217
    Original paper - Journal impact factor: 4.259 (in 2013)
    Abstract
    Link to Pubmed (US
    National Library of Medicine): PMID= 25123808
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1016/j.ijantimicag.2014.05.016 (may require a subscription)

2013

  1. Ampe E, Delaere B, Hecq JD, Tulkens PM, Glupczynski Y
    Implementation of a protocol for administration of vancomycin by continuous infusion: pharmacokinetic, pharmacodynamic, and toxicological aspects.
    International Journal of Antimicrobial Agents (2013) 41:439-446
    Original paper - Journal impact factor: 4.415 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=23523733
    Reprint (with Supplementary Material) PDF (UCL only Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.ijantimicag.2013.01.009 (may require a subscription)

  2. Avrain L, Mertens P, Van Bambeke F
    RND efflux pumps in P. aeruginosa: an underestimated resistance mechanism
    Clinical Laboratory International [Cli-online] (2013) April-May 26-28
    Educational paper
    Reprint (PDF)
    Link to original document: http://www.cli-online.com/ (free subscription)

  3. Bauer J, Siala W, Tulkens PM, Van Bambeke F
    A combined pharmacodynamic quantitative and qualitative model reveals the potent activity of Daptomycin and Delafloxacin against Staphylococcus
    aureus
    biofilms

    Antimicrobial Agents and Chemotherapy (2013) 57:2726-2737
    Original paper - Journal impact factor: 4.565 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=23571532
    Reprint (with Supplementary Material) PDF (UCL only Copyright owned by the publisher) - videos: MSSA - MRSA
    Link to original document through DOI:10.1128/AAC.00181-13 (may require a subscription)

  4. Buyck JM, Tulkens PM, Van Bambeke F
    Pharmacodynamic evaluation of the intracellular activity of antibiotics towards Pseudomonas aeruginosa PAO1 in a model of THP-1 human monocytes
    Antimicrobial Agents and Chemotherapy (2013) 57:2310-2318.
    Original paper - Journal impact factor: 4.565 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID= 23478951
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.02609-12 (may require a subscription)

  5. Buyle FM, Decruyenaere J, De Waele J, Tulkens PM, Van Audenrode T, Depuydt P, Claeys G, Robays H, Vogelaers D
    A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals
    European Journal of Clinical Microbiology and Infectious Diseases (2013) 32:763-768
    Original paper - Journal impact factor: 3.024 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=23271675
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1007/s10096-012-1803-7 (may require a subscription)

  6. Caceres NE, Aerts M, Marquez B, Mingeot-Leclercq MP, Tulkens PM, Devreese B, Van Bambeke F
    Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC)
    PloS ONE (Public Library of Science) (2013) 8(3):e58285.
    Original paper - Journal impact factor: 3.730 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23505477

    Reprint [with part of Supplementary Material] (PDF) - Table S1 - Table S2
    Link to original document through DOI:10.1371/journal.pone.0058285

  7. Catalano A, Carocci A, Defrenza I, Muraglia M, Carrieri C, Van Bambeke F, Filomena Corbo A, Franchini C
    2-Aminobenzothiazole derivatives: Search for new antifungal agents
    European Journal of Medicinal Chemistry (2013) 64C:357-364
    Original paper - Journal impact factor: 3.499 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23644218

    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ejmech.2013.03.064

  8. D'Auria L, Deleu M, Dufour S, Mingeot-Leclercq MP, Tyteca D
    Surfactins modulate the lateral organization of fluorescent membrane polar lipids: A new tool to study drug:membrane interaction and assessment of the role of cholesterol and drug acyl chain length.

    Biochimica et Biophysica Acta (2013) 1828:2064–2073
    Original paper - Journal impact factor: 3.399 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23685123
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2013.05.006


  9. Deleu M, Lorent J, Lins L, Brasseur R, Braun N, El Kirat K, Nylander T, Dufrêne YF, Mingeot-Leclercq MP.
    Effects of surfactin on membrane models displaying lipid phase separation.
    Biochimica et Biophysica Acta (Biomembranes) (2013) 1828:801-15
    Original paper - Journal impact factor: 3.399 (in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23159483
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2012.11.007 (may require a subscription)

  10. Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Denis O, Tulkens PM, Van Bambeke F
    Antibiotic activity against Small Colony Variants of Staphylococcus aureus: Review of in vitro, animal, and clinical data
    Journal of Antimicrobial Chemotherapy (2013) 68:1455-1464
    Review - Journal impact factor: 5.338 (in 2012)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=23485724
    Reprint [with Supplementary Material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkt072 (may require a subscription)

  11. Lorent J, Le Duff CS, Quetin-Leclercq J, Mingeot-Leclercq MP
    Induction of highly curved structures in relation to membrane permeabilization and budding by the triterpenoid saponins, alpha- and delta-hederin..
    Journal of Biological Chemistry (2013) 288:14000-140017
    Original paper - Journal impact factor: 4.651(in 2012)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23530040
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1074/jbc.M112.407635.

  12. Melard A, Garcia LG, Das D, Rozenberg R, Tulkens PM, Van Bambeke F, Lemaire S
    Activity of ceftaroline against extracellular (broth) and intracellular (THP 1 monocytes) forms of methicillin-resistant Staphylococcus aureus: comparison with vancomycin, linezolid and daptomycin.
    Journal of Antimicrobial Chemotherapy (2013) 68: 648–658
    Abstract
    Original paper - Journal impact factor: 5.338 (in 2012)
    Link to PubMed (US National Library of Medicine): PMID=23188792
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dks442 (may require a subscription)

  13. Raverdy V, Ampe E, Hecq JD, Tulkens PM
    Stability and compatibility of vancomycin for administration by continuous infusion.
    Journal of Antimicrobial Chemotherapy (2013) 68:1179-1182.
    Abstract
    Original paper (Brief Report) - Journal impact factor: 5.338 (in 2012)
    Link to PubMed (US National Library of Medicine): PMID=23302579
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:
    10.1093/jac/dks510 (may require a subscription)


  14. Zimmermann L, Bussière A, Ouberai M, Baussanne I, Jolivalt C, Mingeot-Leclercq MP, Décout JL.
    Tuning the Antibacterial Activity of Amphiphilic Neamine Derivatives and Comparison to Paromamine Homologues.
    Journal of Medicinal Chemistry (2013) 56:7691-7705
    Abstract
    Original paper - Journal impact factor: 5.614 (in 2012)
    Link to PubMed (US National Library of Medicine): PMID=24083676
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:
    10.1093/10.1021/jm401148j (may require a subscription)
    .

2012

  1. Baquir B, Lemaire S, Van Bambeke F, Tulkens PM, Lin L, Spellberg B
    Macrophage killing of bacterial and fungal pathogens is not inhibited by intense intracellular accumulation of the lipoglycopeptide antibiotic oritavancin
    Clinical Infectious Diseases (2012) 54 (Suppl 3) S229-S232
    Original paper - Journal impact factor: 9.154
    (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22431853
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/cid/cir921 (may require a subscription)

  2. Buyck JM, Guénard S, Plésiat P, Tulkens PM, Van Bambeke F.
    Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis
    Journal of Antimicrobial Chemotherapy (2012) 67:771-775.
    Original paper (Research Letter) - Journal impact factor: 5.068 (in 2011)
    No abstract available
    Link to PubMed (US National Library of Medicine):PMID=22218683
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkr543 (may require a subscription)

  3. Buyck JM, Plésiat P, Traore H, Vanderbist F, Tulkens PM, Van Bambeke F
    Increased susceptibility of Pseudomonas aeruginosa to macrolides and ketolides in eukaryotic cell culture media and biological fluids (serum,
    bronchoalveolar lavage) by decreased expression of OprM (efflux impairment) and increased outer membrane permeability

    Clinical Infectious Diseases (2012) 55:534-542
    Original paper - Journal impact factor: 9.154 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22573850
    Reprint [with supplementary materail] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/cid/cis473 (may require a subscription)


  4. Claeys C, Nève J, Tulkens PM, Spinewine A.
    Content validity and inter-rater reliability of an instrument to characterize unintentional medication discrepancies.
    Drugs & Aging (2012) 29:577-91.
    Original paper - Journal impact factor: 2.671 (in 2011)
    Abstract

    Link to PubMed (US National Library of Medicine):PMID=22715864
    Reprint (PDF)
    UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.2165/11631980-000000000-00000 (may require a subscription)


  5. Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Denis O, Tulkens PM, Van Bambeke F
    Pharmacodynamic evaluation of the activity of antibiotics against hemin- and menadione-dependent small-colony variants of Staphylococcus aureus in models of extracellular (broth) and intracellular (THP-1 monocytes) infections.
    Antimicrobial Agents and Chemotherapy (2012) 56:3700-3711
    Original paper - Journal impact factor: 4.841 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22564838
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.00285-12 (may require a subscription)

  6. Garcia LG, Lemaire S, Kahl B, Becker K, Proctor RA, Tulkens PM, Van Bambeke F
    Intracellular forms of menadione-dependent Small-Colony Variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to beta-lactams in a model of THP-1 cells due to cooperation between vacuolar acidic pH and oxidant species
    Journal of Antimicrobial Chemotherapy (2012) 67:2873-2881
    Original paper - Journal impact factor: 5.068 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23002174
    Reprint
    [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dks325 (may require a subscription)

  7. Garcia LG, Lemaire S, Kahl B, Becker L, Proctor R, Tulkens PM, Van Bambeke F
    Influence of the protein kinase C activator, phorbol myristate acetate (PMA), on the intracellular activity of antibiotics against hemin and menadione auxotrophic Small-Colony Variant (SCV) mutants of Staphylococcus aureus and their wild-type parental strain in human THP-1 cells
    Antimicrobial Agents and Chemotherapy (2012) 56:6166-6174
    Original paper - Journal impact factor: 4.841 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22985883
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01031-12 (may require a subscription)


  8. Imbuluzqueta E, Lemaire S, Gamazo C, Elizondo E, Ventosa N, Veciana J, Van Bambeke F, Blanco-Prieto MJ
    Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22615297

    Journal of Antimicrobial Chemotherapy (2012) 67:2158-2164
    Original paper - Journal impact factor: 5.068 (in 2011)
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dks172 (may require a subscription)


  9. Jackowski O, Bussière A, Vanhaverbeke C, Baussanne I, Peyrin E, Mingeot-Leclercq MP, Décout JL
    Major increases of the reactivity and selectivity in aminoglycoside O-alkylation due to the presence of fluoride ions
    Tetrahedron (2012) 68:737-746
    Original paper - Journal impact factor: 3.025 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):in process
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.tet.2011.10.102 (may require a subscription)

  10. Kovács E, Savopol T, Iordache MM, Saplacan L, Sobaru I, Istrate C, Mingeot-Leclercq MP, Moisescu MG
    Interaction of gentamicin polycation with model and cell membranes
    Bioelectrochemistry (2012) 87:230–235
    Original paper - Journal impact factor: 3.759 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22522030
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bioelechem.2012.03.001 (may require a subscription)

  11. Lismond A, Carbonnelle S, Verhaegen J, Schatt P, De Bel A, Jordens P, Jacobs F, Dediste A, Verschuren F, Huang D, Tulkens PM, Glupczynski Y, Van Bambeke F
    Antimicrobial susceptibility of Streptococcus pneumoniae isolates from vaccinated and non-vaccinated patients with a clinically-confirmed diagnosis of community-acquired pneumonia (CAP) in Belgium
    International Journal of Antimicrobial Agents (2012) 39:208– 216
    Original paper - Journal impact factor: 4.128 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22245497
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ijantimicag.2011.11.011 (may require a subscription)


  12. Mingeot-Leclercq MP, Tulkens PM, Denamur S, Vaara T, Vaara M
    Novel polymyxin derivatives are less cytotoxic than polymyxin B to renal proximal tubular cells
    Peptides (2012) 35:248–252
    Original paper - Journal impact factor: 2.434 (in 2011)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22504013
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.peptides.2012.03.033 (may require a subscription)

  13. Oumar AA, Diallo K, Dembélé JP, Samaké L, Sidibé I, Togo B, Sylla M, Tounkara A, Dao S, Tulkens PM.
    Adverse drug reactions to antiretroviral therapy: prospective study in children in Sikasso (Mali).
    The Journal of Pediatric Pharmacology and Therapeutics (2012) 17:382-388.
    Original paper (no impact factor)
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=23411444
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.5863/1551-6776-17.4.382


  14. Tulkens PM, Arvis P, Kruesmann, F.
    Moxifloxacin safety: an analysis of 14 years of clinical data
    Drugs in Research and Development (2012) 12:71-100
    Original paper - Journal impact factor: 1.787 (in 2010)
    Link to PubMed (US National Library of Medicine):PMID=22715866
    Reprint [with supplementary material] (PDF) - Open access - Copyright owned by the publisher
    Link to original document through DOI:10.2165/11634300-000000000-00000
  15. Tulkens PM
    Review der Sicherheitsdaten zu Moxifloxacin
    Infection (2012) 40 (Supplement): 61-63
    Symposium Proceeding - Journal impact factor: 2.659 (in 2011)
    Reprint (PDF) - UCL only
    Copyright owned by the publisher

  16.  Van Herendael B, Jeurissen A, Tulkens PM, Vlieghe E, Verbrugghe W, Jorens WG, Ieven M
    Continuous infusion of antibiotics in the critically ill: the new holy grail for beta-lactams and vancomycin?
    Annals of Intensive Care (2012) 2:22 (12 printed pages)

    Review
    Abstract
    Link to PubMed (US National Library of Medicine):PMID=22747633
    Reprint (PDF) - Open access -
    Copyright owned by the publisher
    Link to original document through DOI:10.1186/2110-5820-2-22


2011

  1. Andrade RJ, Tulkens PM
    Hepatic safety of antibiotics used in primary care
    Journal of Antimicrobial Chemotherapy (2011) 66:1431-1446.
    Review - Journal impact factor:
    4.659 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21586591
    Reprint (PDF) - Open access - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkr159
    (open access)

  2. Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerne SAr, Levy S, Lewis K, Lomovskaya O,
    Miller JH, Mobashery S, Piddock LJV, Projan S, Thomas CM, Tomasz A, Tulkens PM, Walsh TR, Watson JD, Witkowski J, Witte W, Wrigh Gt, Yeh P, Zgurskaya HI
    Tackling antibiotic resistance
    Nature Reviews Microbiology (2011) 9:894-896. doi: 10.1038/nrmicro2693
    Essay - Journal impact factor (in 2010): 20.686
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=22048738
    Reprint (PDF) - UCL only -
    Copyright owned by the publisher
    Link to original document through DOI:10.1038/nrmicro2693 (may require a subscription)

  3. Denamur S, Tyteca D, Marchand-Brynaert J, Van Bambeke F, Tulkens PM, Courtoy PJ, Mingeot-Leclercq MP
    Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic.
    Free Radical Biology & Medicine (2011) 51:1656-1665
    Original paper - Journal impact factor: 5.707 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21835240
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.freeradbiomed.2011.07.015
    (may require a subscription)


  4. Lemaire S, Kosowska-Shick K, Appelbaum PC, Glupczynski Y, Van Bambeke F, Tulkens PM
    Activity of moxifloxacin against intracellular community-acquired methicillin-resistant Staphylococcus aureus: comparison with clindamycin, linezolid and co-trimoxazole and attempt at defining an intracellular susceptibility breakpoint.
    Journal of Antimicrobial Chemotherapy (2011) 66:596-607
    Original paper - Journal impact factor:
    4.659 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21186193
    Reprint (PDF) - Open access - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkr159
    (may require a subscription)


  5. Lemaire S, Tulkens PM, Van Bambeke F.
    Contrasting effect of acidic pH on the extracellular and intracellular activity of anti-Gram-positive fluoroquinolones (moxifloxacin and delafloxacin) against Staphylococcus aureus.
    Antimicrobial Agents and Chemotherapy (2011) 55:649-58.
    Original paper - Journal impact factor:
    4.672 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21135179
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01201-10
    (may require a subscription)

  6. Lemaire S, Van Bambeke F, Pierard D, Appelbaum PC, Tulkens PM
    Activity of CEM-102 (fusidic acid) towards extracellular and intracellular Staphylococcus aureus: Influence of pH and comparison with linezolid and clindamycin.
    Clinical Infectious Diseases (2011) 52 Suppl 7:S493-503.
    Original paper (in Supplement section) - Journal impact factor: 8.186 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21546626
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher

    Link to original document through DOI:10.1093/cid/cir165
    (may require a subscription


  7. Lemaire S, Van Bambeke F, Tulkens PM
    Activity of finafloxacin, a novel fluoroquinolone with increased activity at acid pH, towards extracellular and intracellular Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila
    International Journal of Antimicrobial Agents (2011) 38:52-59.
    Original paper - Journal impact factor:
    3.787 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21596526
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ijantimicag.2011.03.002
    (may require a subscription)


  8. Lismond A, Carbonnelle S, Tulkens PM, Van Bambeke F
    Efflux of novel quinolones in contemporary Streptococcus pneumoniae isolates from community-acquired pneumonia
    Journal of Antimicrobial Chemotherapy (2011) 66:948-951
    Original paper (Research Letter) - Journal impact factor: 4.659 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21393137
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkr004
    (may require a subscription)

  9. Marquez B, Van Bambeke F.
    ABC multidrug transporters: Target for modulation of drug pharmacokinetics and drug-drug interactions
    .
    Current Drug Targets (2011) 12:600-620
    Review paper - Journal impact factor 4.187 (in 2009; paper submitted in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21039335
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher

    Whole Issue (PDF) -
    UCL only - Copyright owned by the publisher

  10. Marquez B, Ameye G, Vallet CM, Tulkens PM, Poirel HA, Van Bambeke F
    Characterization of Abcc4 gene amplification in stepwise-selected mouse J774 macrophages resistant to the topoisomerase II inhibitor ciprofloxacin
    PLoS ONE (Public Library of Science) 6:e28368
    Original paper - Journal impact factor (in 2010): 4.411
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=22162766
    Reprint [with supplementary material] (PDF) - Open access - Copyright owned by the publisher

    Link to original document through DOI:10.1371/journal.pone.0028368.1016 (open access)

  11. Ouberai M, El Garch F, Bussiere A, Riou M, Alsteens D, Lins L, Baussanne I, Dufrêne YF, Brasseur R, Decout JL, Mingeot-Leclercq MP.
    The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?
    Biochimica Biophysica Acta - Biomembranes (2011) 1808:1716-1727
    Original paper - Journal impact factor: 4.647 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21291859
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2011.01.014
    (may require a subscription)

  12. Rolin C, Hecq, JD, Tulkens P, Vanbeckbergen D, Jamart J, Galanti L
    Long-term stability of temocillin in dextrose 5% and in sodium chloride 0.9% polyolefin bags at 5 +/- 3°C after freeze-thaw treatment
    Annales Pharmaceutiques Françaises (2011) 69:296-301
    Original paper - Journal impact factor: not available
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=22115132
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.pharma.2011.09.004
    (may require a subscription)


  13. Sandberg A, Lemaire S, Van Bambeke F, Tulkens PM, Hughes D, von Eiff C, Frimodt-Møller, N
    Intra- and extracellular activity of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with small-colony variant phenotype in an in vitro (THP-1 macrophages) and an in vivo mouse peritonitis model
    Antimicrobial Agents and Chemottherapy (2011) 55:1443-1452
    Original paper - Journal impact factor: 4.672 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21282430
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.00205-10
    (may require a subscription)

  14. Vallet CM, Marquez B, Ngabirano E, Lemaire S, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F
    Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin, and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages.
    International journal of Antimicrobial Agents (2011) 38:249-256.
    Original paper - Journal impact factor:
    3.787 (in 2010)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21764262
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ijantimicag.2011.05.011
    (may require a subscription)

  15. Vallet CM, Marquez B, Nhiri N, Anantharajah A, Mingeot-Leclercq M-P, Tulkens PM, Lallemand J-Y, Jacquet E, Van Bambeke F
    Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin
    Toxicology (2011) 290:179-187
    Original paper - Journal impact factor (in 2010): 3.65
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21946100
    Reprint [with supplementary material] (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.tox.2011.09.003
    (may require a subscription)

  16. Van Bambeke F
    ABC transporters: role in modulation of drug pharmacokinetics and in physiopathology and therapeutic perspectives (Editorial)
    Current Drug Targets (2011) 12:598-599
    Editorial - Journal impact factor 4.187 (in 2008; submission early 2009)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=21039339
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    Whole Issue (PDF) -
    UCL only - Copyright owned by the publisher


2010

  1. Baudoux P, Lemaire S, Denis O, Tulkens PM, Van Bambeke F, Glupczynski Y
    Activity of quinupristin-dalfopristin against extracellular and intracellular Staphylococcus aureus with various resistance phenotypes

    Journal of Antimicrobial Chemotherapy (2010) 65:1228-1236
    Original paper - Journal impact factor: 4.352 (in 2009)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20378672
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkq110 (may require a subscription)


  2. Baussanne I, Bussière A, Halder S, Ganem-Elbaz C, Ouberai M, Riou M, Paris JM, Ennifar E, Mingeot-Leclercq MP, Décout JL.
    Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives.

    Journal of Medicinal Chemistry (2010) 14:119-127
    Original paper - Journal impact factor (in 2008 [last known]): 4.898
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20000576
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1021/jm900615h
    (may require a subscription)

  3. Becker JP, Van Bambeke F, Tulkens PM, Prévost M.
    Dynamics and structural changes induced by ATP binding in SAV1866, a bacterial ABC exporter.
    Journal of Physical Chemistry B (2010) 114:15948-15957
    Original paper -
    Journal impact factor: 4.189 (in 2009)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=21069970
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1021/jp1038392
    (may require a subscription)


  4. Berthoin K, Le Duff CS, Marchand-Brynaert J, Carryn S, Tulkens PM
    Stability of meropenem and doripenem solutions for administration by continuous infusion
    Journal of Antimicrobial Chemotherapy (2010) 65:1073-1075
    Original paper (Research Letter) - Journal impact factor: 4.352 (in 2009)
    Link to PubMed (US National Library of Medicine): PMID=20176578
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkq044 (may require a subscription)

  5. Bernal P, Lemaire S, Pinho MG, Mobashery S, Hinds J, Taylor PW
    Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin binding protein (PBP) 2a-mediated ß-lactam resistance by delocalizing PBP2

    Journal of Biological Chemistry (2010) 285:24055-24065
    Original paper - Journal impact factor: 5.328 (in 2009)
    Link to PubMed (US National Library of Medicine): PMID=20516078
    Reprint with supplemental material (PDF) - Free Text - Copyright owned by the publisher
    Link to original document through DOI:10.1074/jbc.M110.114793 (may require a subscription)

  6. Brinch KS, Tulkens PM, Van Bambeke F, Frimodt-Møller N, Høiby N, Kristensen HH
    Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin
    Journal of Antimicrobial Chemotherapy (2010) 65:1720-1724.
    Original paper (Brief report) - Journal impact factor: 4.3652 (in 2009)

    Link to PubMed (US National Library of Medicine): PMID=20534628
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkq159 (may require a subscription)


  7. Carryn S, Couwenbergh B, Tulkens PM
    Long-term Stability of Temocillin in Elastomeric Pumps for Outpatient Antibiotic Therapy (OPAT) in Cystic Fibrosis (CF) Patients.

    Journal of Antimicrobial Chemotherapy (2010) 65:2045-2046
    Original paper (Research Letter) - Journal impact factor: 4.352 (in 2009)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20576638
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkq229 (may require a subscription)


  8. Domenech O, Dufrêne Y, Van Bambeke F, Tulkens PM, Mingeot-Leclercq MP
    Interactions of oritavancin, a new semi-synthetic lipoglycopeptide, with lipids extracted from Staphylococcus aureus.
    Biochimica et Biophysica Acta - Biomembranes (2010) 1798:1876-1885
    Original paper - Journal impact factor: 3.998 (in 2009)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20599683
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2010.06.011 (may require a subscription)


  9. El Garch F, Lismond A, Piddock LJV, Courvalin P, Tulkens PM, Van Bambeke F
    Fluoroquinolones induce the expression of patA and patB which encode ABC efflux pumps in Streptococcus pneumoniae

    Journal of Antimicrobial Chemotherapy (2010) 65:2076-82
    Original paper - Journal impact factor: 4.352 (in 2009)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID= 20709735
    Reprint with supplemental material and erratum (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI: 10.1093/jac/dkq287 (may require a subscription)


  10. Gordon C, Van Bambeke F
    Azithromycin
    In: Kucers's the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs
    6th Edition, volume 1, pages 801-818, 2010, Edward Arnold (Publishers) Ltd.
    Introduction
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  11. Langan C, Van Bambeke F
    Clarithromycin
    In: Kucers's the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs
    6th Edition, volume 1, pages 779-800, 2010, Edward Arnold (Publishers) Ltd.
    Introduction
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  12. Lemaire S, Tulkens PM, Van Bambeke F
    Cellular pharmacokinetics of the novel biaryloxazolidinone radezolid in phagocytic cells: studies with macrophages and polymorphonuclear neutrophils.
    Antimicrobial Agents and Chemotherapy (2010) 54:2540-2548
    Original paper - Journal impact factor: 4.716 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20385873
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01723-09 (may require a subscription)

  13. Lemaire S, Kosowska-Shick K, Appelbaum PC, Verween G, Tulkens PM, Van Bambeke F
    Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila.

    Antimicrobial Agents and Chemotherapy (2010) 54:2549-2559
    Original paper - Journal impact factor: 4.716 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20385852
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01724-09 (may require a subscription)

  14.   In French Oumar AA, Jnaoui K, Yombi JC, Kabamba BM, Ruelle J, Tulkens PM, Wallemacq P, Goubau P.
    L'infection par le virus de l'immunodéficience humaine (VIH) et son traitement au Mali
    Louvain Médical (2010) 129: 116-122
    Educational paper
    Abstract
    Reprint (PDF) (UCL only - Copyright owned by the publisher)

  15. Riou M, Carbonnelle S, Avrain L, Mesaros N, Pirnay JP, Bilocq F, De Vos D, Simon A, Pierard D, Jacobs F, Dediste A, Tulkens PM, Van Bambeke F, Glupczynski Y
    In vivo development of antimicrobial resistance in Pseudomonas aeruginosa strains isolated from lower respiratory tract of intensive care unit patients with nosocomial pneumonia and receiving antipseudomonal therapy
    International Journal of Antimicrobial Agents
    Original paper - Journal impact factor: 3.032 (in 2009)

    International Journal of Antimicrobial Agents (2010) 36:513-522
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20926262
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ijantimicag.2010.08.005 (may require a subscription)


  16. Sandberg A, Jensen KS, Baudoux P, Van Bambeke F, Tulkens PM, Frimodt-Møller N
    Intra- and extracellular activity of dicloxacillin against Staphylococcus aureus in vivo and in vitro.
    Antimicrobial Agents and Chemotherapy (2010) 54:2391-2400
    Original paper - Journal impact factor: 4.716 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20308386
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01400-09 (may require a subscription)


  17. Sandberg A, Jensen KS, Baudoux P, Van Bambeke F, Tulkens PM, Frimodt-Møller N
    Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro
    Journal of Antimicrobial Chemotherapy (2010) 65:962-973
    Original paper - Journal impact factor: 4.352 (in 2009)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20211859
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkq052 (may require a subscription)


  18. Staes E, Absil PA, Lins L, Brasseur R, Deleu M, Lecouturier N, Fievez V, des Rieux A, Mingeot-Leclercq MP, Raussens V, Préat V.
    Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: towards a better understanding of the underlying mechanisms.
    Biochimica Biophysica Acta - Biomembranes. (2010) 1798::2102-13.
    Original paper - Journal impact factor: 3.998 (in 2009)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20637180
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2010.07.002 (may require a subscription)

  19. Van Bambeke F, Pagès J-M, Lee VJ
    Inhibitors of bacterial efflux pumps as adjuvants in antibacterial therapy and diagnostic tools for detection of resistance by efflux

    In: Frontiers in Anti-Infective Drug Discovery (2010) vol. 1, 138-175,
    Atta-ur-Rahman & M. Iqbal Choudhary (Eds.), Bentham Science Publishers.
    Chapter of book
    Abstract
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  20. Van Bambeke F, Glupczynski, Y, Mingeot-Leclercq, MP, Tulkens PM
    Mechanisms of Action.
    In: Infectious Diseases (3d edition; J. Cohen, W. Powderly & S. Opal, eds), chapter 130, pp 1288-1307, Elsevier/Mosby, 2010 (ISBN 978-0-323-04579-7)
    Chapter of book
    Reprint (PDF) with references - UCL only - Copyright owned by the publisher
    Available on line at http://www.expertconsultbook.com (requires a subscription)

  21. Van Bambeke F
    Erythromycin
    In: Kucers's the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs
    6th Edition, volume 1, pages 751-769, 2010, Edward Arnold (Publishers) Ltd.
    Introduction
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  22. Van Bambeke F
    Roxithromycin
    In: Kucers's the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs
    6th Edition, volume 1, pages 770-778, 2010, Edward Arnold (Publishers) Ltd.
    Introduction
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  23. Van Bambeke F
    Josamycin and rosaramicin
    In: Kucers's the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs
    6th Edition, volume 1, pages 819-824, 2010, Edward Arnold (Publishers) Ltd.
    Introduction
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2009

  1. Becker JP, Depret G, Van Bambeke F, Tulkens PM, Prevost M
    Molecular models of human P-glycoprotein in two different catalytic states
    BMC Structural Biology (2009) 9:3
    Original paper - Journal impact factor: 2.000 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19159494
    Reprint (PDF) - Open access
    Link to original document through DOI:10.1186/1472-6807-9-3 (open access)

  2. Berthoin K, Ampe E, Tulkens PM, Carryn S
    Correlation between free and total vancomycin serum concentrations in patients treated for Gram-positive infections.
    International Journal of Antimicrobial Agents (2009) 34:555-60.
    Original paper - Journal impact factor: 3.067 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19782538
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.ijantimicag.2009.08.005 (may require a subscription)

  3. Brinch KS, Sandberg A, Baudoux P, Van Bambeke F, Tulkens PM, Frimodt-Møller N, Høiby N, Kristensen HH
    Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in the mouse peritonitis model.
    Antimicrobial Agents and Chemotherapy (2009) 53:4801-4808
    Original paper - Journal impact factor: 4.716 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19738011
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.00685-09 (may require a subscription)

  4. Domenech O, Francius G, Tulkens PM, Van Bambeke F, Dufrene Y, Mingeot-Leclercq MP
    Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: effect on membrane permeability and nanoscale lipid membrane organization.
    Biochimica et Biophysica Acta - Biomembranes (2009) 1788:1832-1840
    Original paper - Journal impact factor: 4.180 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19450541
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.bbamem.2009.05.003 (may require a subscription)

  5. In French Feron JM, Legrand D, Pestiaux D, Tulkens PM
    Prescription d’antibiotiques en médecine générale en Belgique et en France: entre déterminants collectifs et responsabilité individuelle

    Pathologie Biologie (Paris) (2009) 57:61-64. .
    Review - Journal impact factor: 0.960 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18848403
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1016/j.patbio.2008.07.002 (may require a subscription)

  6. Franchini C, Muraglia M, Corbo F, Florio MA, Di Mola A, Rosato A, Matucci R, Nesi M, van Bambeke F, Vitali C.
    Synthesis and biological evaluation of 2-mercapto-1,3-benzothiazole derivatives with potential antimicrobial activity
    Archiv der Pharmazie - Chemistry in Life Sciences (Weinheim) (2009) 342:605-613
    Original paper - Journal impact factor: 1.429 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19753564
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1002/ardp.200900092 (may require a subscription)


  7. Lemaire S, Glupczynski Y, Duval V, Joris B, Tulkens PM, Van Bambeke F
    Activity of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages, keratinocytes) forms of Methicillin-Sensitive (MSSA) and Methicillin-Resistant Staphylococcus aureus (MRSA).
    Antimicrobial Agents and Chemotherapy (2009) 53:2289-2297
    Original paper - Journal impact factor (in 2008): 4.716
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19289525
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:
    10.1128/AAC.01135-08 (may require a subscription)

  8. Lemaire S, Van Bambeke F, Tulkens PM.
    Cellular accumulation and pharmacodynamic evaluation of the Intracellular activity of CEM-101, a novel fluoroketolide, towards Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages.
    Antimicrobial Agents and Chemotherapy (2009) 53:3734-3743
    Original paper - Journal impact factor: 4.716 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19564365
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.00203-09 (may require a subscription)

  9. Lemaire S, Van Bambeke F, Appelbaum P.C., Tulkens PM
    Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines.
    Journal of Antimicrobial Chemotherapy (2009) 64:1035-1043
    Original paper - Journal impact factor: 4.238 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19759040
    Reprint with supplemental material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkp267 (may require a subscription)

  10. Lemaire S, Tulkens PM, Van Bambeke F.
    Therapeutic options for intracellular MRSA: Current views and perspectives
    In: Methicillin-Resistant Staphylococcus Aureus (MRSA): Etiology, At-Risk Populations and Treatment (C.L. Kolendi, ed.), chapter 2, pp 55-74
    ISBN: 978-1-60741-398-1
    Chapter of book
    Provisional reprint (PDF)
    Reprint (PDF) UCL only - Copyright owned by the publisher
    (not yet available)

  11. Livermore DM, Tulkens PM
    Temocillin revived
    Journal of Antimicrobial Chemotherapy (2009) 63:243-245
    Review - Journal impact factor: 4.238 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19095679
    Reprint (PDF) - Open access - Copyright owned by the publisher
    Link to original document through DOI:10.1093/jac/dkn511 (free access)

  12. Marquez B, Caceres NE, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F.
    Identification of the efflux transporter of the fluoroquinolone antibiotic ciprofloxacin in murine macrophages: studies with ciprofloxacin-resistant cells

    Antimcrobial Agents and Chemotherapy (2009) 53: 2410-2416
    Original paper - Journal impact factor (in 2008): 4.716
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19307362
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:
    10.1128/AAC.01428-08 (may require a subscription)

  13. Nguyen HA, Denis O, Vergison A, Theunis A, Tulkens PM, Struelens MJ, Van Bambeke F
    Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus Small Colony Variant isolated from a cystic fibrosis patient : 1. Pharmacodynamic evaluation and comparison with isogenic normal phenotype and revertant strains.
    Antimicrobial Agents and Chemotherapy (2009) 53:1434–1442
    Original paper - Journal impact factor (in 2008): 4.716
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=19188393
    Reprint with supplementary material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01145-08 (may require a subscription)

  14. Nguyen HA, Denis O, Vergison A, Tulkens PM, Struelens MJ, Van Bambeke F
    Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus Small Colony Variant isolated from a cystic fibrosis patient : 2. Study of antibiotic combinations.
    Antimicrobial Agents and Chemotherapy (2009) 53:1443-1449
    Original paper - Journal impact factor (in 2008): 4.716
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=19188397
    Reprint with supplementary material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1128/AAC.01146-08 (may require a subscription)

  15. Olivier AC, Lemaire S, Van Bambeke F, Tulkens PM, Oldfield E
    Role of rsbU and staphyloxanthin in phagocytosis and intracellular growth of Staphylococcus aureus in human macrophages and endothelial cells.
    Journal of Infectious Diseases (2009) 200:1367-1370
    Original paper - Journal impact factor: 5.375 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19817587
    Reprint with supplementary material (PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1086/606012 (may require a subscription)


  16. Tytgat I, Colacino E, Tulkens PM, Poupaert JH, Prévost M, Van Bambeke F
    DD-Ligases as a Potential Target for Antibiotics: Past, Present and Future
    Current Medicinal Chemistry (2009) 16: 2566-2580
    Review - Journal impact factor: 4.823 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19601798
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  17. Tytgat I, Vandevuer S, Ortmans I, Sirockin F, Colacino E, Van Bambeke F, Duez C, Poupaert JH, Tulkens PM, Dejaegere A, Prévost M
    Structure-based design of benzoxazoles as new inhibitors for D-alanyl - D-alanine ligase
    QSAR and Combinatorial Sciences (2009) 28: 1394-1404

    Original paper - Journal impact factor: 2.594 (in 2008)
    Abstract
    Reprint (PDF) (with supplementary materia) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.1002/qsar.200910054 (may require a subscription)


  18. Van Bambeke F, Tulkens PM.
    Safety profile of moxifloxacin, a respiratory fluoroquinolone: comparison with other fluoroquinolones and other antibiotic classes

    Drug Safety (2009) 32:359-378
    Review paper - Journal impact factor (in 2008): 3.597
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=19419232
    Reprint (restricted PDF) - UCL only - Copyright owned by the publisher
    Link to original document through DOI:10.2165/00002018-200932050-00001 (may require a subscription)

  19. In French Van Bambeke F, Tulkens PM
    Pharmacodynamie des antibiotiques dans le LCR : principes et conséquences (facteurs prédictifs d'efficacité
    Médecine et maladies infectieuses (2009) 39:483-492
    Educational paper
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19500928
    Reprint (PDF) - UCL only - Copyright owned by the publisher
    link to original document through DOI:10.1016/j.medmal.2009.02.038 (may require a subscription)

  20. Glycopeptides (Dalbavancin, Oritavancin, Teicoplanin, Telavancin, Vancomycin) - Update 2009
    Van Bambeke F, Virgincar N, MacGowan A. Glycopeptides (Dalbavancin, Oritavancin, Teicoplanin, Telavancin, Vancomycin) - Update 2009
    Antimicrobial Therapy and Vaccines. Vol. II: Antimicrobial Agents (2009) 42pp
    V.L. Yu et al. eds
    Web edition (
    Esun Technologies), Pittsburgh, PA (http://www.antimicrobe.org - requires a subscription)
    Reprint (PDF) - UCL only - Copyright owned by the publisher

  21. New Van de Velde S, Carryn S, Van Bambeke F, Hill C, Tulkens PM, Sleator RD
    Penicillin-binding Proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in beta-lactam sensitivity of Listeria monocytogenes.
    Gut Pathogens (2009) 1:23
    Original paper - Journal impact factor: not in ISI 2008 list

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=20003484
    Reprint (PDF) - Open access - Copyright owned by the publisher
    link to original document through DOI:10.1186/1757-4749-1-23 (free access)

  22. Van de Velde S, Delaive E, Dieu M, Carryn S, Van Bambeke F, Devreese B, Raes M, Tulkens PM.
    Isolation and 2D-DIGE proteomic analysis of intracellular and extracellular forms of Listeria monocytogenes.
    Proteomics (2009) 9:5484-5496
    Original paper - Journal impact factor: 4.585 (in 2008)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=19834917
    Reprint (PDF) (with Supplementary Material) - UCL only - Copyright owned by the publisher
    link to original document through DOI:10.1002/pmic.2009005030 (may require a subscription)


2008

  1. Barcia-Macay M, Mouaden F, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F
    Cellular pharmacokinetics of telavancin, a novel lipoglycopeptide antibiotic, and analysis of lysosomal changes in cultured eukaryotic cells (J774 mouse macrophages; rat embryonic fibroblasts).
    Journal of Antimicrobial Chemotherapy (2008) 61:1288-1294
    Original paper - Journal impact factor: 4.038 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18375379
    Reprint (PDF) (Open access - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkn120 (Open access)

  2. Bensikaddour H, Snoussi K, Lins L, Brasseur R, Van Bambeke F, Tulkens PM, Goormaghtigh E, Mingeot-Leclercq MP
    Interactions of ciprofloxacin with DPPC and DPPG: Fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis
    Biochimica Biophysica Acta (Biomembranes) (2008) 1778:2535-2543
    Original paper - Journal impact factor: 3.640 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18809375
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:
    10.1016/j.bbamem.2008.08.015 (may require a subscription)

  3. Bensikaddour H, Fa N, Burton I, Deleu M, Lins L, Schanck A, Brasseur R, Dufrêne YF, Goormaghtigh E, Mingeot-Leclercq MP
    Characterization of the interactions between fluoroquinolone antibiotics and lipids: a multitechnique approach
    Biophysical Journal (2008) 94:3035-3046
    Original paper - Journal impact factor: 4.627 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18178657
    Reprint (PDF) (Open access - Copyright owned by the publisher)
    Link to original document through DOI:10.1529/biophysj.107.114843 (may require a subscription)

  4. Brasseur R, Deleu M, Mingeot-Leclercq MP, Francius G, Dufrêne YF
    Probing peptide–membrane interactions using AFM
    Surface and Interface Analysis (2008) 40:151–156
    Original paper - Journal impact factor:
    1.036 (in 2007)
    Abstract
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1002/sia.2682 (may require a subscription)

  5. De Jongh R, Hens R, Basma V, Mouton JW, Tulkens PM, Carryn S
    Continuous vs intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
    Journal of Antimicrobial Chemotherapy (2008) 61:382-388
    Original paper - Journal impact factor: 4.038 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18070831
    Reprint (PDF) (with supplementary material - UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1093/jac/dkm467 (may require a subscription)

  6. Denamur S, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM
    Apoptosis induced by aminoglycosides in LLC-PK1 cells: comparison between neomycin, gentamicin, amikacin, and isepamicin using electroporation.
    Antimicrobial Agents and Chemotherapy (2008) 52:2236–2238
    Original paper - Journal impact factor (last known): 4.390 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18391041
    Reprint (PDF) (with supplementary material - UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.01680-07 (may require a subscription)

  7. Francius G, Domenech O, Mingeot-Leclercq MP, Dufrêne YF.
    Direct observation of Staphylococcus aureus cell wall digestion by lysostaphin

    Journal of Bacteriolology (2008) 190:7904-7909
    Original paper - Journla impact factor: 4.013 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18835985
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/JB.01116-08 (may require a subscription)

  8. Francius G, Dufour S, Deleu M, Paquot M, Mingeot-Leclercq MP, Dufrêne YF.
    Nanoscale membrane activity of surfactins: influence of geometry, charge and hydrophobicity.
    Biochimica et Biophysica Acta - Biomembranes (2008) 1778:2058-2068.
    Original paper - Journla impact factor: 3.815 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18455997
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.bbamem.2008.03.023 (may require a subscription)


  9. Kent L, Bradley JM, France M, Döring G, Carryn S, Bradbury I, Rendall J, Jones A, Elborn JS.
    Temocillin in cystic fibrosis: A retrospective pilot study.
    Journal of Cystic Fibrosis (2008) 7:551-554
    Original paper - Journal impact factor: not known (new journal)
    Abstract
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.jcf.2008.06.005 (may require a subscription)

  10. Lemaire S, Fuda C, Van Bambeke F, Tulkens PM, Mobashery S
    Restoration of susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics by acidic pH: role of penicillin-binding-protein 2A (PBP 2A)
    Journal of Biological Chemistry (2008) 283:12769-12776
    Original paper - Jounal impact factor: 5.581 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18337244
    Reprint (PDF) (with supplementary material - UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1074/jbc.M800079200 (may require a subscription)

  11. Lemaire S, Kosowska-Shick K, Julian K, Tulkens PM, Van Bambeke F, Appelbaum PC
    Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of S. aureus isolates from a patient with persistent bacteraemia and endocarditis

    Clinical Microbiology and Infection (2008) 14:766-777
    Original paper - Journal impact factor: 2.980 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18727801
    Reprint (PDF) (with supplementary material - UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1111/j.1469-0691.2008.02035.x (may require a subscription)

  12. Lemaire S, Olivier A, Van Bambeke F, Tulkens PM, Appelbaum PC, Glupczynski Y.
    Restoration of susceptibility of intracellular Methicillin Resistant Staphylococcus aureus (MRSA) to beta-lactams: comparison between strains, cells, and antibiotics
    Antimicrobial Agents and Chemotherapy (2008) 52:2997-2805
    Original paper - Journal impact factor: 4.390 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18519727
    Reprint (PDF) (with supplementary material- UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.00123-08 (may require a subscription)

  13. Lismond A, Tulkens PM, Mingeot-Leclercq MP, Courvalin P, Van Bambeke, F.
    Cooperation between prokaryotic (Lde) and eukaryotic (MRP) efflux transporters in J774 macrophages infected with Listeria monocytogenes. Studies with ciprofloxacin and moxifloxacin.
    Antimicrobial Agents and Chemotherapy (2008) 52:3040-3046
    Origina paper - Journal impact factor: 4.390 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18573933
    Reprint (PDF) (with supplementary material - UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.00105-08 (may require a subscription)


  14. Mouton JW, Theuretzbacher U, Craig WA, Tulkens PM, Derendorf H, Cars O
    Tissue concentrations: do we ever learn?
    Journal of Antimicrobial Chemotherapy (2008) 61:235-237.
    Review - Journal impact factor: 4.038 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18065413
    Reprint (PDF) (free - Copyright owned by the publisher)
    Link to original document through DOI:10.1093/jac/dkm476 (free)

  15. Servais H,. Ortiz A, Devuyst O, Denamur S, Tulkens PM, Mingeot-Leclercq M-P
    Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation.
    Apoptosis (2008) 13:11-32.
    Review - Journal impact factor: 3.043 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17968659
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1007/s10495-007-0151-z (may require a subscription)


  16. In French Van Bambeke F.
    L'ABC des hépatites virales
    Journal de Pharmacie de Belgique (2008) 63:15-20
    Educational paper
    Abstract
    Reprint (PDF) (UCL only - Copyright owned by the publisher)

  17. Van Bambeke F, Harms J, Van Laethem Y, Tulkens PM.
    Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections
    Expert Opinion on Pharmacotherapy (2008) 9:267-283
    Review paper - Journal impact factor: 1.703 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18201149
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1517/14656566.9.2.267 (may require a subscription)


  18. Van Bambeke F, Mingeot-Leclercq MP, Struelens MJ, Tulkens PM.
    The bacterial envelope as a target for novel anti-MRSA antibiotics

    Trends in Pharmacological Sciences (TIPS) (2008) 29:124-134
    Review paper - Journal impact factor: 9.610 (in 2007)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18262289
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.tips.2007.12.004 (may require a subscription)

  19. Van de Velde S, Nguyen HA, Van Bambeke F, Tulkens PM, Grellet J, Dubois V, Quentin C, Saux, MC.
    Contrasting effects of human THP-1 cells differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes.

    Journal of Antimicrobial Chemotherapy (2008) 62:518-521
    Original paper (Brief Note) - Journal impact factor: 4.038 (in 2007)

    Abstract
    Link to PubMed (US National Library of Medicine): PMID=18544595
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1093/jac/dkn232 (may require a subscription)


2007

  1. Avrain L, Garvey M, Mesaros N, Glupczynski Y, Mingeot-Leclercq MP, Piddock LJV, Tulkens PM, Vanhoof R, Van Bambeke F
    Selection of quinolone resistance in Streptococcus pneumoniae exposed in vitro to sub-inhibitory drug concentrations.
    Journal of Antimicrobial Chemotherapy (2007) 60:965-972
    Original paper - Journal impact factor: 3.891(last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17693451
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1093/jac/dkm292 (may require a subscription)


  2. Baudoux P, Bles N, Lemaire S, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F.
    Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections.
    Journal of Antimicrobial Chemotherapy (2007) 59:246-53
    Original paper - Journal impact factor: 3.886 (last known)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=17220162
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1093/jac/dkl489 (may require a subscription)

  3. Brasseur R, Braun N, El Kirat K, Deleu M, Mingeot-Leclercq MP, Dufrêne Y
    The biologically important surfactin lipopeptide induces nanoripples in supported lipid bilayers
    Langmuir (2007) 23:9769-9772
    Original paper - Journal impact factor: 3.902
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17696376
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1021/la7014868 (may require a subscription)


  4. Fa N, Lins L, Courtoy PJ, Dufrêne Y, Van Der Smissen P, Brasseur R, Tyteca D, Mingeot-Leclercq MP.
    Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin.
    Biochimica Biophysica Acta [Biomembranes] (2007) 1768:1830-1838.
    Original paper - Journal impact factor: 3.587 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID= 17537401
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.bbamem.2007.04.013 (may require a subscription)

  5. Hernout O, Berthoin K, Delattre I, Tulkens PM, Carryn S, Marchand-Brynaert J
    Design and evaluation of analogues of the bacterial cell-wall peptidoglycan motif L-Lys-D-Ala-D-Ala for use in a vancomycin biosensor
    Bioorganic & Medicinal Chemistry Letters (2007) 17:5758–5762
    Original paper - Journal impact factor: 2.538 (last knwon)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17855088
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.bmcl.2007.08.055 (may require a subscription)

  6. Lemaire S, Van Bambeke F, Mingeot-Leclercq MP, Glupczynski Y, Tulkens PM
    Role of Acidic pH in the Susceptibility of Intraphagocytic Methicillin-Resistant Staphylococcus aureus Strains to
    Meropenem and Cloxacillin
    Antimicrobial Agents and Chemotherapy (2007) 51:1627-1632.
    Original paper - Journal impact factor: 4.153 (in 2006)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17307986
    Reprint (PDF) (Free access - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.01192-06 (may require a subscription)

  7. Lemaire S, Van Bambeke F, Mingeot-Leclercq M-P, Tulkens PM.
    Modulation of the Cellular Accumulation and Intracellular Activity of Daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) Efflux Transporter in human THP-1 macrophages and Madin-Darby canine kidney cells.
    Antimicrobial Agents and Chemotherapy (2007) 51:2748-2757
    Original paper - Journal impact factor: 4.153 (in 2006)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17548493
    Reprint (PDF) (Free access - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.00090-07 (may require a subscription)

  8. Mallet L, Spinewine A, Huang A
    The challenge of managing drug interactions in elderly people
    Lancet. (2007) 370:185-91.
    Review - Journal impact factor: 25.800 (last known)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=17630042
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/S0140-6736(07)61092-7 (may require a subscription)


  9. Mathot F, Schanck A, Van Bambeke F, Ariën A, Noppe M, Brewster M, Préat V.
    Passive diffusion of polymeric surfactants across lipid bilayers.
    Journal of Controlled Release (2007) 120:79-87
    Original paper - Journal impact factor: 4.012
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17524515
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/j.jconrel.2007.03.015 (may require a subscription)


  10. Mesaros N, Glupczynski Y, Avrain L, Caceres NE, Tulkens PM, Van Bambeke F.
    A combined phenotypic and genotypic method for the detection of Mex efflux pumps in Pseudomonas aeruginosa.
    Journal of Antimicrobial Chemotherapy (2007) 59:378-386.
    Original paper - Journal impact factor: 3.886 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17289770
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkl504 (may require a subscription)

  11.  Mesaros N, Nordmann P, Plésiat P, Roussel-Delvallez M, Van Eldere J, Glupczynski Y, Van Laethem Y, Jacobs F, Lebecque P, Malfroot A, Tulkens PM, Van Bambeke F.
    Pseudomonas aeruginosa
    : resistance and therapeutic options at the turn of the new millennium.
    Clinical Microbiology and Infection (2007) 13: 560–578
    Review - Journal impact factor: 2.679 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17266725
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1111/j.1469-0691.2007.01681.x (may require a subscription)

     In French versions françaises: Pseudomonas aeruginosa : résistance et options thérapeutiques à l'aube du nouveau millénaire.
    • Antibiotiques [Paris] (2007) 9:189-198 -- Tiré-à-part (PDF)
    • Louvain-Médical (Bruxelles) -- Tiré-à-part (PDF)

  12. Spinewine A, Swine C, Dhillon S, Lambert P, Nachega J, Wilmotte L, Tulkens PM.
    Impact of a collaborative approach on the quality of prescribing for geriatric inpatients. A randomized controlled trial.
    Journal of the American Geriatrics Society (2007) 55:658–665
    Original paper - Journal impact factor: 3.479 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17493184
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1111/j.1532-5415.2007.01132.x (may require a subscription)

  13. Spinewine A, Schmader KE, Barber N, Hughes C, Lapane KL, Swine C, Hanlon JT
    Appropriate prescribing in elderly people: how well can it be measured and optimised?
    Lancet. (2007) 370:173-84.
    Review - Journal impcat factor: 25.800 (last known)
    Abstract

    Link to PubMed (US National Library of Medicine): PMID=17630041
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1016/S0140-6736(07)61091-5 (may require a subscription)

  14. Van Bambeke F, Reinert RR, AppelbaumPC, Tulkens PM, Peetermans WE
    Multidrug-Resistant Streptococcus pneumoniae infections: current and future therapeutic options.
    Drugs (2007) 67:2355-2382 Review - Journal impact factor: 4.472 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17983256
    Reprint (PDF) (UCL only - Copyright owned by the publisher)
    Supplementary material: PDF

2006

  1. In Dutch Ampe E, Spinewine A, Tulkens PM.
    Klinische Farmacie, een positieve ontwikkeling op de weg naar een betere patiëntenzorg in de Belgische ziekenhuizen.
    Tijdschrift voor Geneeskunde (2006) 62:1273-1284
    Educational paper
    Abstract
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  2. In French  Ampe E, Spinewine A, Wilmotte L, Hecq JD, et Tulkens PM
    La Pharmacie clinique: un développement récent de l'activité des pharmaciens pour une prise en charge optimisée des patients du point de vue médicamenteux.

    Louvain Médical (2006) 125:275-290
    Educational paper
    Abstract
    Reprint (PDF) (UCL only - Copyright owned by the publisher)

  3. Barcia-Macay M, Seral C, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F.
    Pharmacodynamic evaluation of the intracellular activity of antibiotics against Staphylococcus aureus in a model of THP-1 macrophages.
    Antimicrobial Agents and Chemotherapy (2006) 50:841-851
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=16495241
    Reprint (PDF file) (Free access - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.50.3.841-851.2006
    (may require a subscription)

  4. Barcia-Macay M, Lemaire S, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F.
    Evaluation of the Extracellular and Intracellular Activities (human THP-1 macrophages) of Telavancin vs. Vancomycin against Methicillin-susceptible, Methicillin-resistant, Vancomycin-intermediate and Vancomycin-resistant Staphylococcus aureus

    Journal of Antimicrobial Chemotherapy (2006) 58:1177–1184
    Original paper - Journal impact factor: 3.886 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17062609
    Reprint (PDF file) (Open Access - available for non-commercial use)
    Link to original document through DOI: 10.1093/jac/dkl424
    (Open Access - available for non-commercial use)

  5. Charvalos E, Tzatzarakis MN, Van Bambeke F, Tulkens PM, Tsatsakis AM, Tzanakakis GN, Mingeot-Leclercq MP.
    Water-soluble amphotericin B-polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects.
    Journal of Antimicrobial Chemotherapy (2006) 57:236-244
    Original paper - Journal impact factor: 3.611 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=16361329
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dki455
    (may require a subscription)

  6. Fa N, Ronkart S, Schanck A, Deleu M, Gaigneaux A, Goormaghtigh E, Mingeot-Leclercq MP.
    Effect of the antibiotic azithromycin on thermotropic behavior of DOPC or DPPC bilayers.
    Chem Phys Lipids (2006) 144:108-16.
    Original paper - Journal impact factor: 2.351 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=17007828
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.chemphyslip.2006.08.002
    (may require a subscription)

  7. Michot JM, Heremans MF, Caceres NE, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F
    Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages.
    Antimicrobial Agents and Chemotherapy (2006) 50:1689-1695
    Original paper - Journal impact factor: 4.246 (last known)
    Asbtract
    Link to PubMed (US National Library of Medicine): PMID=16641436
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.50.5.1689-1695.2006
    (may require a subscription)

  8. Servais H, Jossin Y, Van Bambeke F, Tulkens PM, Mingeot-Leclercq MP
    Gentamicin causes apoptosis at low concentrations in renal LLC-PK1 cells subjected to electroporation
    Antimicrobial Agents and Chemotherapy (2006) 50:1213-1221
    Original paper - Journal impact factor: 4.246 (last known)
    Asbtract
    Link to PubMed (US National Library of Medicine): PMID=1656983
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.50.4.1213-1221.2006
    (may require a subscription)

  9. Spinewine A, Dhillon S, Mallet L, Tulkens PM, Wilmotte L, Swine C.
    Implementation of ward-based clinical pharmacy services in Belgium - Description of the impact on a geriatric unit.

    Annals of Pharmacotherapy (2006) 40:720-728
    Original paper - Journal impact factor (last known): 1.739
    Asbtract
    Link to PubMed (US National Library of Medicine): PMID=16569792
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1345/aph.1G515
    (may require a subscription)

  10. Van Bambeke F.
    Glycopeptides and glycodepsipeptides in clinical developement: a comparative of their antibacterial spectrum, pharmacokinetics and clinical efficacy.
    Current Opinion in Investigational Drugs (2006) 7:740-749
    Review - Journal impact factor: new Journal (no impact factor known in 2006)
    Abstract
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  11. Van Bambeke F, Barcia-Macay M, Lemaire S, Tulkens PM
    Cellular pharmacokinetics and pharmacodynamics of antibiotics: current views and perspectives
    Current Opinion in Drug Discovery & Development (2006) 9:218-230
    Review - Journal impact factor: 3.698 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=16566292
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  12. Van Bambeke F, Pagès J-M, Lee VJ
    Inhibitors of bacterial efflux pumps as adjuvants in antibiotic treatments and diagnostic tools for detection of resistance by efflux.

    Recent Patents on Anti-Infective Drug Discovery (2006) 1:157-175.
    Review
    paper - New Journal (no impact factor known in 2006)
    Abstract
    Indexed in Chemical Abstracts
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  13. Vandevuer S, Van Bambeke F, Tulkens PM, Prévost M
    Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying cross-linking data: insight into the mechanism of ligand migration and binding sites.

    Proteins (Proteins-structure function and bioinformatics) (2006) 63:466-478
    Original paper - Journal impact factor: 4.429 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=16463278
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1002/prot.20892 (may require a subscription)
    Supporting information: Protein DataBank file 617 Kb (pdb file; can be opened with Viewer Lite of Accelrys/SciFinder)

     


2005

  1. Berquand A, Fa N, Dufrêne YF, Mingeot-Leclercq M-P
    Interaction of the macrolide antibiotic azithromycin with lipid bilayers: effect on membrane organization, fluidity, and permeability.
    Pharmaceutical Research (2005) 22:465-475
    Original paper - Journal impact factor: 2.940 (in 2004)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15835753
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1007/s11095-004-1885-8 (may require a subscription)

  2. Block S, Gerkens P, Peulen O, Jolois O, Mingeot-Leclercq M-P, De Paux-Gillet M-CL, Quetin-Leclercq J
    Induction of apoptosis in human promyelocytic leukemia cells by a natural trachylobane diterpene.
    Anticancer Research (2005) 25:363-368
    Original paper - Journal impact factor: 1.395 (in 2004)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15816559
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  3. Chanteux H, Van Bambeke F, Mingeot-Leclercq M-P,  Tulkens PM
    Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethyl ester prodrug (PIVA).
    Antimicrobial Agents and Chemotherapy (2005)49:1279-88.
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15589222 
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.49.4.1279-1288.2005
    (may require a subscription)

  4. Lemaire S, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM
    Activity of 3 beta-lactams (ertapenem, meropenem, and ampicillin) against intraphagocytic L. monocytogenes and S. aureus

    Journal of Antimicrobial Chemotherapy (2005) 55:897–904
    Original paper - Journal impact factor: 3.611 (last known)

    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15860552
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dki094
    (may require a subscription)

  5. In Dutch Mesaros N, Van Bambeke F, Avrain L, Glupczynski G, Vanhoof R, Tulkens PM
    Actieve efflux van antibiotica en bacteriële resistentie: actualisatie en  implicaties

    Tijdschrift voor Geneeskunde (2005) 61:1407-1417
    Educational paper
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  6. In French Mesaros N, Van Bambeke F, Avrain L, Glupczynski Y, Vanhoof R, Plesiat P, Tulkens PM
    L'efflux actif des antibiotiques et la résistance bactérienne: état de la question et implications
    La Lettre de l'Infectiologue (2005) 20:117-126
    Educational paper
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  7. In French Mesaros N, Van Bambeke F, Glupczynski Y, Vanhoof R, Tulkens PM
    L'efflux actif des antibiotiques et la résistance bactérienne: état de la question et implications microbiologiques et cliniques
    Louvain Médical (2005) 124:308-320
    Educational paper
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  8. Michot JM, Seral C, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM.
    Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages.
    Antimicrobial Agents and Chemotherapy (2005) 49:2429-2437
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15917543
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI:10.1128/AAC.49.6.2429-2437.2005
    (may require a subscription)

  9. Mulazimoglu L, Tulkens PM, Van Bambeke F
    Macrolides
    In: Antimicrobial Therapy and Vaccines. Vol. II: Antimicrobial Agents, 2005. V.L. Yu, G. Edwards, P.S. McKinnon, C. Peloquin, & G.D. Morse, editors. Esun Technologies, Pittsburgh, PA. pp. 243-283.
    Chapter of book.
    Reprint (PDF) (UCL only - Copyright owned by the publisher)

  10. Piret J, Schank A, Delfosse S, Van Bambeke F, Kishore BK, Tulkens PM, Mingeot-Leclercq M-P
    Modulation of the in vitro activity of lysosomal phospholipase A1 by membrane lipids.
    Chemistry and Physics of Lipids (2005) 133:1-15
    Original paper - Journal impact factor: 2.164 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15589222 
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.chemphyslip.2004.08.002
    (may require a subscription)

  11. Seral C,  Barcia-Macay M,  Mingeot-Leclercq MP,  Tulkens PM, Van Bambeke F
    Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin, and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages.
    Journal of Antimicrobial Chemotherapy (2005) 55:511-517
    Original paper - Journal impact factor: 3.080 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15731197 
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: doi:10.1093/jac/dki059
    (may require a subscription)

  12. Servais H, Mingeot-Leclercq MP, and Tulkens PM
    Antibiotic-induced nephrotoxicity
    In: Toxicology of the Kidney (Target Organ Toxicology Series), 2004, chap. 16, pp 635-685, J.B. Tarloff & L.H. Lash, eds., CRC Press, Boca Raton, Fla., ISBN 0-415-24864-7
    chapter of book
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  13. Servais H, Van Der Smissen P, Thirion G, Van der Essen G, Van Bambeke F, Tulkens PM, Mingeot-Leclercq MP
    Gentamicin-induced apoptosis in LLC-PK1 cells: involvement of lysosomes and mitochondria
    Toxicology and Applied Pharmacolology (2005) 15:321-333
    Original paper - Journal impact factor: 2.993 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15731197 
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.taap.2004.11.024
    (may require a subscription)

  14. Spinewine A, Swine C, Dhillon S, Franklin DB, Tulkens PM, Wilmotte L, Lorant V
    Appropriateness of use of medicines in elderly inpatients: qualitative study
    British Medical Journal (2005) 331:935-940
    Original paper - Journal impact factor: 7.038 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=16093254 
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1136/bmj.38551.410012.06 (may require a subscription)

  15. Van Bambeke F, Michot JM, Van Eldere J, Tulkens PM
    Quinolones in 2005: an update 
    Clinical Microbiology and Infection (2005) 11:256-280 - Erratum published
    : 11:513, 2005
    Review paper - Journal impact factor: 2.238 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15760423 
    Reprint (PDF file)
    - Erratum (PDF-File) (UCL only - Copyright owned by the publisher) -
    Link to original document through DOI: doi:10.1111/j.1469-0691.2005.01131.x
      --  Erratum: doi: 10.1111/j.1469-0691.2005.01192.x
    (may require a subscription)

  16. Van Bambeke F, Saffran J, Mingeot-Leclercq MP, Tulkens PM
    Mixed lipid storage disorder induced in macrophages and fibroblasts by oritavancin (LY333328), a new glycopeptide antibiotic with exceptional cellular accumulation.

    Antimicrobial Agents and Chemotherapy (2005) 49:1695-1700.
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract 
    Link to PubMed (US National Library of Medicine): PMID=15855483 
    Reprint (PDF file)
    (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: doi:10.1128/AAC.49.5.1695-1700.2005
    (may require a subscription)


2004

  1. Bauraind I, Lopez-Lozano J-M, Beyaert A, Marchal J-L, Yane F, Goossens H, Tulkens PM, Verbist L
    Association between antibiotic sales and public campaigns for their appropriate use.
    JAMA-Journal of the American Medical Association (2004) 24:2468-2470
    Original paper - Journal impact factor: 21.455 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15562124
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  2. Ben Abdelaziz HB, Lemaire S, Carryn S, Van Bambeke F, Mingeot-Leclercq M-P, Tulkens PM
    Inhibition of TNF-alpha production in THP-1 macrophages by glatiramer acetate does not alter their susceptibility to infection by Listeria monocytogenes and does not impair the efficacy of ampicillin or moxifloxacin against intracellular bacteria.
    Journal of Antimicrobial Chemotherapy (2004) 54:288-289
    Original paper - Journal impact factor: 3.080 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15190038
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkh288 (may require a subscription)

  3. Berquand A, Mingeot-Leclercq M-P, Dufrêne YF
    Real-time imaging of drug-membrane interactions by atomic force microscopy.
    Biochimica et Biophysica Acta (Biomembranes) (2004) 1664:198-205
    Original paper - Journal impact factor: 3.243 (in 2003) - Contributing unit(s): FACM (see key)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15328052
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.bbamem.2004.05.010 (may require a subscription)

  4. Carryn S, Van de Velde S, Van Bambeke F, Mingeot-Leclercq M-P, Tulkens PM
    Impairment of growth of listeria monocytogenes in THP-1 macrophages by granulocyte macrophage colony-stimulating factor : release of tumor necrosis factor-a and nitric oxide.
    The Journal of Infectious Diseases (2004) 189:2101-2109
    Original paper - Journal impact factor: 4.857 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15143479
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)

  5. De Clercq E, Tulkens P
    Anti-infectives.
    Current Opinion in Pharmacology (2004) 4:429-430
    Review paper - - Journal impact factor: 4.593 (last known)
    Link to PubMed (US National Library of Medicine): PMID=15351345
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.coph.2004.08.002 (may require a subscription)

  6. Michot J-M, Van Bambeke F, Mingeot-Leclercq M-P, Tulkens PM
    Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter.
    Antimicrobial Agents and Chemotherapy (2004) 48:2673-2682
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15215125
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.48.7.2673-2682.2004 (may require a subscription)

  7. Nassogne M-C, Lizarraga C, N'Kuli F, Van Bambeke F, Van Binst R, Wallemacq P, Tulkens PM, Mingeot-Leclercq M-P, Courtoy PJ
    Cocaine induces a mixed lysosomal lipidosis in cultured fibroblasts, by inactivation of acid sphingomyelinase and inhibition of phospholipase A1.
    Toxicology and Applied Pharmacology (2004) 194:101-110
    Original paper - Journal impact factor: 2.993 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=14736491
    Link to original document through DOI: 10.1016/j.taap.2003.09.026 (may require a subscription)

  8. In French Spinewine A, Schoevaerdts D, Choteau B, Doyen C, Swine C
    Le traitement de la douleur chez la personne agée.
    Association des Soins Palliatifs en Province de Namur (2004) 11:17-24
    Original paper

  9. Van Bambeke F
    Glycopeptides in clinical development: pharmacological profile and clinical perspectives.
    Current Opinion in Pharmacology (2004) 4:471-478
    Review paper - - Journal impact factor: 4.593 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15351351
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/j.coph.2004.04.006 (may require a subscription)

  10. Van Bambeke F, Carryn S, Seral C, Chanteux H, Tyteca D, Mingeot-Leclercq M-P, Tulkens PM
    Cellular pharmacokinetics and pharmacodynamics of the glycopeptide antibiotic oritavancin (LY333328) in a model of J774 mouse macrophages.
    Antimicrobial Agents and Chemotherapy (2004) 48:2853-2860
    Original paper - Journal impact factor: 4.246 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15273091
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1128/AAC.48.8.2853-2860.2004 (may require a subscription)

  11. Van Bambeke F, Van Laethem Y, Courvalin P, Tulkens PM
    Glycopeptide antibiotics: from conventional molecules to new derivatives.
    Drugs (2004) 64:913-936
    Review paper - Journal impact factor: 5.368 (last known)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=15101783
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)


2003

  1. Baririan N, Chanteux H, Viaene E, Servais H, Tulkens PM
    Stability and compatibility of cefepime in comparison with ceftazidime for administration by continuous infusion for ambulatory treatment of cystic fibrosis patients and for administration in intensive care units (abridged title).
    Journal of Antimicrobial Chemotherapy (2003) 51:651-658
    Original paper - Journal impact factor: 3.329 (in 2002) 
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12615867
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkg134 (may require a subscription)

  2. Carryn S, Chanteux H, Seral C, Mingeot-Leclercq M-P, Van Bambeke F, Tulkens PM
    Intracellular pharmacodynamics of antibiotics.
    Infectious Disease Clinics of North America (2003) 17:615-634
    Review paper - Journal impact factor: 1.781 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=14711080
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1016/SO891-5520(03)00066-7 (may require a subscription)

  3. Carryn S, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM
    Activity of beta-lactams (ampicillin, meropenem), gentamicin, azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a 24h THP-1 human macrophage model.
    Journal of Antimicrobial Chemotherapy (2003) 51:1051-1052
    Letter to the Editor or short commentary - Journal impact factor: 3.329 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12654747
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkg189 (may require a subscription)

  4. Chanteux H, Mingeot-Leclercq M-P, Sonveaux E, Van Bambeke F, Tulkens PM
    Intracellular accumulation and activity of ampicillin used as free drug and as its phthalimidomethyl or pivaloyloxymethyl ester (pivampicillin) against Listeria monocytogenes in J774 macrophages.
    Journal of Antimicrobial Chemotherapy (2003) 52:610-615
    Original paper - Journal impact factor: 3.329 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12972457
    Reprint (PDF file) (UCL only - Copyright owned by the publisher)
    Link to original document through DOI: 10.1093/jac/dkg431 (may require a subscription)

  5. Chanteux H, Paternotte I, Mingeot-Leclercq M-P, Brasseur R, Sonveaux E, Tulkens PM
    Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basics esters of ampicillin, in comparison with chloroquine and azithromycin.
    Pharmaceutical Research (2003) 20:624-631
    Original paper - Journal impact factor: 2.354 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12739771
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  6. Dom G, Shaw-Jackson C, Matis C, Bouffioux O, Picard JJ, Prochiantz A, Mingeot-Leclercq MP, Brasseur R, Rezsohazy R
    Cellular uptake of antennapedia penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation.
    Nucleic Acids Research (2003) 31:556-561
    Original paper - Journal impact factor: 7.051 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12527762
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    Link to original document through DOI: 10.1093/nar/gkg160 (may require a subscription)

  7. Mingeot-Leclercq MP, Lins L, Bensliman M, Thomas A, Van Bambeke F, Peuvot J, Schank A, Brasseur R
    Piracetam inhibits the lipid-destabilising effect of the amyloid peptide A beta C-terminal fragment.
    Biochimica et Biophysica Acta (Biomembranes) (2003) 1609:28-38
    Original paper - Journal impact factor: 3.011 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12507755
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    Link to original document through DOI: 10.1016/s0005-2736(02)00654-5 (may require a subscription)

  8. Seral C, Carryn S, Tulkens PM, Van Bambeke F
    Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus.
    Journal of Antimicrobial Chemotherapy (2003) 51:1167-1173
    Original paper - Journal impact factor: 3.329 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12697643
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    Link to original document through DOI: 10.1093/jac/dkg223 (may require a subscription)

  9. Seral C, Michot JM, Chanteux H, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F
    Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages.
    Antimicrobial Agents and Chemotherapy (2003) 47:1047-1051
    Original paper - Journal impact factor: 4.215 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12604540
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    Link to original document through DOI: 10.1128/AAC.47.3.1047-1051.2003 (may require a subscription)

  10. Seral C, Van Bambeke F, Tulkens PM
    Quantitative analysis of gentamicin, azithromycin, telithromycin, ciprofloxacin, moxifloxacin and oritavancin (LY333328) activities against intracellular Staphylococcus aureus in mouse J774 macrophages.
    Antimicrobial Agents and Chemotherapy (2003) 47:2283-2292
    Original paper - Journal impact factor: 4.215 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12821480
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    Link to original document through DOI: 10.1128/aac.47.7.2283-2292.2003 (may require a subscription)

  11. In French Spinewine A
    La pharmacie clinique, une nouvelle orientation pharmaceutique au service des patients: réalisations à l'étranger et possibilités en Belgique.
    Louvain Médical (2003) 122:127-139
    Educational paper
    Abstract
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  12. Spinewine A, Mallet L
    Pharmaceutical care in the aged: illustration of the process in patients hospitalized in Canada.
    Journal de Pharmacie de Belgique (2003) 58:21-27
    Original paper
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12722541

  13. In French Spinewine A, Mallet L
    Effet de la simvastatine sur la mortalité et la morbidité chez 20 536 patients à risque élevé de mortalité cardio-vasculaire.
    Pharmactuel (2003) 36:10-13
    Educational paper
    Abstract

  14. Tyteca D, Schank A, Dufrene YF, Deleu M, Courtoy PJ, Tulkens PM, Mingeot-Leclercq M-P
    The macrolide antibiotic azithromycin ineracts with lipids and affects membrane organization and fluidity: studies on Langmuir-Blodgett monolayers, liposomes and J774 macrophages.
    Journal of Membrane Biology (2003) 192:203-215
    Original paper - Journal impact factor: 2.440 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12820665

  15. Van Bambeke F, Glupczynski Y, Plésiat P, Pechère JC, Tulkens PM
    Antibiotic efflux pumps in prokaryotic cells : occurence, impact on resistance and strategies for the future of antimicrobial therapy.
    Journal of Antimicrobial Chemotherapy (2003) 51:1055-1065
    Review paper - Journal impact factor: 3.329 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12697642
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    Link to original document through DOI: 10.1093/jac/dkg224 (may require a subscription)

  16. Van Bambeke F, Lambert DM, Mingeot-Leclercq M-P, Tulkens PM
    Mechanims of action.
    In: Infectious Diseases 2, Cohen Jonathan ed., Mosby, 1717-1732 (2003) ISBN 978-0323024075
    Chapter of book/Proceeding

  17. Van Bambeke F, Michot JM, Tulkens PM
    Antibiotic efflux pumps in eukaryotic cells: occurence and impact on antibiotic cellular pharmacokinetics, pharmacodynamics and toxicodynamics.
    Journal of Antimicrobial Chemotherapy (2003) 51:1067-1077
    Review paper - Journal impact factor: 3.329 (in 2002)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12697641
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    Link to original document through DOI: 10.1093/jac/dkg225 (may require a subscription)


2002

  1. Carryn S, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM
    Comparative intracellular (THP-1 Macrophage) and extracellular activities of beta-lactams, azithromycin, gentamicin, and fluoroquinolones against Listeria monocytogenes at clinically relevant concentrations.
    Antimicrobial Agents and Chemotherapy (2002) 46:2095-2103
    Original paper - Journal impact factor: 4.562 (in 2001)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12069960
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    Link to original document through DOI: 10.1128/AAC.46.7.2095-2103.2002 (may require a subscription)

  2. Mingeot-Leclercq MP, Lins L, Bensliman M, Van Bambeke F, Van Der Smissen P, Peuvot J, Schank A, Brasseur R
    Membrane destabilisation induced by beta-amyloid peptide 29-42: importance of the amino-terminus.
    Chemistry and Physics of Lipids (2002) 120:57-74
    Original paper - Journal impact factor: 2.164 (in 2001)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12426076
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  3. Spinewine A, Dean B
    Measuring the impact of medicines information services on patient care: methodological considerations.
    Pharmacy World & Science (2002) 24:177-181
    Review paper - Journal impact factor: 0.633 (in 2001)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12426961

  4. Spinewine A, Dhillon S
    Clinical pharmacy practice: implications for pharmacy education in Belgium.
    Pharmacy Education (2002) 2:75-81
    Original paper - Journal impact factor: new journal no impact factor known in 2002.
    Abstract

  5. Tyteca D, Van Der Smissen P, Mettlen M, Van Bambeke F, Tulkens PM, Mingeot-Leclercq MP, Courtoy PJ
    Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages.
    Experimental Cell Research (2002) 281:86-100
    Original paper - Journal impact factor: 5.096 (in 2001)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12441132
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  6. In French Van Bambeke F, Tulkens P
    Médicaments anti-infectieux dans les pathologies infectieuses du SNC.
    In: Neuro-infectiologie, C. Sindic ed., Doin Editions, 355-388 (2002)
    Chapter of book
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  7. Viaene E, Chanteux H, Servais H, Mingeot-Leclercq MP, Tulkens PM
    Comparative stability studies of antipseudomonal beta-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor-operated syringes (intensive care units).
    Antimicrobial Agents and Chemotherapy (2002) 46:2327-2332
    Original paper - Journal impact factor: 4.562 (in 2001)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=12121900
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2001

  1. Gholizadeh Y, Prévost M, Van Bambeke F, Casadewall B, Tulkens PM, Courvalin P
    Sequencing the ddl gene and modeling of the mutated D-alanine:D-alanine ligase in glycopeptide-dependent strains of Enterococcus faecium.
    Protein Science (2001) 10:836-844
    Original paper - Journal impact factor: 3.869 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11274474
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  2. Mingeot-Leclercq MP, Gallet X, Flore C, Van Bambeke F, Peuvot J, Brasseur R
    Experimental and conformational analyses of interactions between butenafine and lipids.
    Antimicrobial Agents and Chemotherapy (2001) 45:3347-3354
    Original paper - Journal impact factor: 3.954 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11709307
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  3. Paternotte I, Fan HJ, Scrève P, Claesen M, Tulkens PM, Sonveaux E
    Syntheses and hydrolysis of basic and dibasic ampicillin esters tailored for intracellular accumulation.
    Bioorganic & Medicinal Chemistry (2001) 9:493-502
    Original paper - Journal impact factor: 1.799 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11249141
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  4. Servais H, Tulkens PM
    Stability and compatibility of ceftazidime administered by continuous infusion to intensive care patients.
    Antimicrobial Agents and Chemotherapy (2001) 45:2643-2647
    Original paper - Journal impact factor: 3.954 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11502544
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  5. Tyteca D, Van der Smissen P, Van Bambeke F, Leys K, Tulkens PM, Courtoy PJ, Mingeot-Leclercq MP
    Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts.
    European Journal of Cell Biology (2001) 80:466-478
    Original paper - Journal impact factor: 2.801 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11499789
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  6. Van Bambeke F, Tulkens PM
    Macrolides: pharmacokinetics and pharmacodynamics.
    International Journal of Antimicrobial Agents (2001) 18:S17-S23
    Review paper - Journal impact factor: 1.141 (in 2000)
    Abstract
    Link to PubMed (US National Library of Medicine): PMID=11574190
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  7. In French Van Bambeke F, Verhaegen J, Tulkens PM
    Erythromycine, autres macrolides et kétolides: usages cliniques actuels et perspectives.
    La Lettre de l'Infectiologue (2001) 16:318-328
    Educational paper
    Abstract

  8. In Dutch Van Bambeke F, Verhaegen J, Tyteca D, Auckenthaler R, Tulkens PM
    Erythromycine en de huidige neomacroliden: klinisch gebruik en perspectieven.
    Tijdscrift voor Geneeskunde (2001) 57:382-395
    Educational paper
    Abstract

  9. In French Van Bambeke F, Verhaegen J, Tyteca D, Auckenthaler R, Tulkens PM
    Erythromycine et néomacrolides actuels, usages cliniques et perspectives.
    Médecine & Hygiène (2001) 59:2316-2323
    Educational paper
    Abstract


2000

  1. El Mouedden M, Laurent G, Mingeot-Leclercq M-P, Tulkens PM
    Gentamicin-induced apoptosis in renal cell lines and embryonic rat fibroblasts.
    Toxicological Sciences (2000) 56:229-239
    Original paper - Journal impact factor: 1.778 (in 1999)
    Abstract
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  2. El Mouedden M, Laurent G, Mingeot-Leclercq MP, Taper HS, Cumps J, Tulkens PM
    Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides.
    Antimicrobial Agents and Chemotherapy (2000) 44:665-675
    Original paper - Journal impact factor: 3.969 (in 1999)
    Abstract
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  3. Prévost M, Van Belle D, Tulkens PM, Courvalin P, Van Bambeke F
    Modeling of Enterococcus faecalis D-alanine:D-alanine ligase: structure based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutant.
    Journal of Molecular Microbiology and Biotechnology (2000) 2:321-330
    Original paper - Journal impact factor: 2.438 (in 2002; new journal with no impact factor known in 2000).
    Abstract
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  4. Tulkens PM
    New strategies to avoid development of microbial resistance.
    In: Ochsner Clinic Symposium on Resistance and the Use and Misuse of Antimicrobial Therapy, G.A. Pankey and G.D. Campbell Jr ed., A.M.M. & Co., Inc., Newtown, PA, 44-52 (2000)
    Chapter of book/Proceeding

  5. In French Van Bambeke F, Courvalin P
    Coût biologique de la résistance aux antibiotiques: vancomycine-dépendance, le prix ultime bactérien ?.
    La Lettre de l'Infectiologue (2000) 15:285-294
    Educational paper
    Abstract

  6. Van Bambeke F, Balzi E, Tulkens PM
    Antibiotic efflux pumps.
    Biochemical Pharmacology (2000) 60:457-470
    Review paper - Journal impact factor: 2.755 (in 1999)
    Abstract
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  7. Van Bambeke F, Kerkhofs A, Schanck A, Remacle C, Sonveaux E, Tulkens PM, Mingeot-Leclercq MP
    Biophysical studies and intracellular destabilization of pH-sensitive liposomes.
    Lipids (2000) 35:213-223
    Original paper - Journal impact factor: 2.040 (in 1999)
    Abstract
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    (UCL only - Copyright owned by the publisher)

  8. In French Van Bambeke F, Verhaegen J, Tyteca D, Auckenthaler R, Tulkens PM
    Erythromycine et némacrolides actuels: usages cliniques et perspectives.
    Louvain Médical (2000) 119:259-286
    Educational paper
    Abstract
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