Université Catholique de Louvain (UCL-Bruxelles)

Department of Pharmaceutical Sciences
Cellular and Molecular Pharmacology Unit (Dir. Prof. P.M. Tulkens)
Original papers, by reverse chronological order
(Full Papers published in Peer-reviewed Scientific Journals)
Last update: 30/12/2000
See also the indexed search or go back to the previous page for a list of our Abstracts, Reviews, Chapter of Books, Proceedings, Books, PhD Theses, Master Degree Dissertations, or Educational papers.
  1. Gentamicin-induced apoptosis in renal cell lines and embryonic rat fibroblasts.
    El Mouedden M, Laurent G, Mingeot-Leclercq MP, Tulkens PM
    Tox Sci (2000) 56:229-239. Journal impact factor: 1.778 (in 1999)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  2. Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides.
    El Mouedden M, Laurent G, Mingeot-Leclercq MP, Taper HS, Cumps J, Tulkens PM
    Antimicrob Agents Chemother (2000) 44:665-675. Journal impact factor: 3.761 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  3. Modeling of the Enterococcus faecalis D-alanine:D-alanine ligase: Structure-based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutants.
    Prévost M, Van Belle D, Tulkens PM, Courvalin P, Van Bambeke F
    J Mol Microbiol Biotechnol (2000) 2:321-330. Journal impact factor: not known (new journal)
    Abstract

  4. Biophysical studies and intracellular destabilization of pH-sensitive liposomes.
    Van Bambeke F, Kerkhofs A, Schanck A, Remacle C, Sonveaux E, Tulkens PM, Mingeot-Leclercq MP
    Lipids (2000) 35:213-223. Journal impact factor: 2.040 (in 1999)
    Abstract

  5. Saccharomyces boulardii upgrades cellular adaptation following proximal enterectomy in rats.
    Buts J-P, De Keyser N, Marandi S, Hermans D, Sokal EM, Chae Y-HE, Lambotte L, Chanteux H, Tulkens PM
    Gut (1999) 45:89-96. Journal impact factor: 5.111 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  6. Interactions of macrolide antibiotics (erythromycin A, roxithromycin, erythromycylamine and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models.
    Montenez JP, Van Bambeke F, Piret J, Brasseur R, Tulkens PM, Mingeot-Leclercq MP
    Toxicol Applied Pharmacol (1999) 156:129-140. Journal impact factor: 2.654 (in 1998)
    Abstract

  7. Mechanism of the intracellular killing and modulation of antibiotic susceptibility of Listeria monocytogenes in THP-1 macrophages activated by gamma-interferon.
    Ouadrhiri Y, Scorneaux B, Sibille Y, Tulkens PM
    Antimicrob Agents Chemother (1999) 43:1242-1251. Journal impact factor: 3.761 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  8. Modulation of intracellular growth of Listeria monocytogenes in human enterocyte-like Caco-2 cells by interferon-gamma and interleukin-6: role of nitric oxide and cooperation with antibiotics.
    Ouadrhiri Y, Sibille Y, Tulkens PM
    J Infect Dis (1999) 180:1195-1204. Journal impact factor: 4.966 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  9. Vancomycin-dependent Enterococcus faecalis clinical isolates and revertant mutants.
    Van Bambeke F, Chauvel M, Reynolds PE, Fraimow HS, Courvalin P
    Antimicrob Agents Chemother (1999) 43:41-47. Journal impact factor: 3.761 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  10. Computer-aided prediction of macrolide antibiotic concentrations in human circulating polymorphonuclear leucocytes.
    Bouvier d'Yvoire MJY, Dresco IA, Tulkens PM
    J Antimicrob Chemother (1998) 41:63-68. Journal impact factor: 2.563
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  11. Lysosomal alterations induced in cultured rat fibroblasts by long-term exposure to low concentrations of azithromycin.
    Van Bambeke F, Gerbaux C, Michot J-M, Bouvier d'Yvoire M, Montenez JP, Tulkens PM
    J Antimicrob Chemother (1998) 42:761-767. Journal impact factor: 2.563
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  12. Ester prodrugs of ampicillin tailored for intracellular accumulation.
    Fan HJ, Paternotte I, Vermander M, Li K, Beaujean M, Scorneaux B, Dumont P, Tulkens PM, Sonveaux E
    Bioorg Med Chem Lett (1997) 7:3107-3112. Journal impact factor: 1.628
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  13. Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation.
    Gerbaux C, Van Bambeke F, Montenez JP, Piret J, Morlighem G, Tulkens PM
    FEBS Lett (1996) 394:307-310. Journal impact factor: 3.750
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  14. Mechanism of the thesaurismosis and altered lysosomal dynamics induced by poly-D-glutamic acid in kidney proximal tubular cells.
    Kishore BK, Fuming L, Maldague P, Tulkens PM, Courtoy PJ
    Lab Invest (1996) 74:1025-1037. Journal impact factor: 4.640
    Abstract

  15. Poly-D-glutamic acid induces an acute lysosomal thesaurimosis in proximal tubules and a marked proliferation of interstitium in rat kidney.
    Kishore BK, Maldague P, Tulkens PM, Courtoy PJ
    Lab Invest (1996) 74:1013-1023. Journal impact factor: 4.640
    Abstract

  16. Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies.
    Montenez JP, Van Bambeke F, Piret J, Schanck A, Brasseur R, Tulkens PM, Mingeot-Leclercq MP
    Eur J Pharmacol (1996) 314:215-227. Journal impact factor: 2.339
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  17. Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1.
    Scorneaux B, Ouadrhiri Y, Anzalone G, Tulkens PM
    Antimicrob Agents Chemother (1996) 40:1225-1230. Journal impact factor: 3.797
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  18. Aminoglycoside antibiotics prevent the formation of non bilayer structures in negatively-charged membranes. Comparative studies using fusogenic [bis-(beta-diethylaminoethylether)hexestrol] and aggregating (spermine) agents.
    Van Bambeke F, Mingeot-Leclercq M-P, Brasseur R, Tulkens PM, Schanck A
    Chem Phys Lipids (1996) 79:123-135. Journal impact factor: 2.118
    Abstract

  19. Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity.
    Van Bambeke F, Montenez JP, Piret J, Tulkens PM, Courtoy PJ, Mingeot-Leclercq MP
    Eur J Pharmacol (1996) 314:203-214. Journal impact factor: 2.339
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  20. Synthesis and antimicrobial and toxicological studies of amino acid and peptide derivatives of kanamycin A and netilmicin.
    Kotretsou S, Mingeot-Leclercq M-P, Constantinou-Kokotou V, Brasseur R, Georgiadis MP, Tulkens PM
    J Med Chem (1995) 38:4710-4719. Journal impact factor: 4.146
    Abstract

  21. Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes.
    Van Bambeke F, Tulkens PM, Brasseur R, Mingeot-Leclercq MP
    Eur J Pharmacol (1995) 289:321-333. Journal impact factor: 2.637

  22. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture.
    Carlier MB, Garcia-Luque I, Montenez J-P, Tulkens PM, Piret J
    Int J Tiss React (1994) 16:211-220.
    Abstract

  23. Urinary phospholipids excretion in neonates treated with amikacin.
    Ibrahim S, Langhendries JP, Bernard A, Tulkens PM
    Int J Clin Pharm Res (1994) 14:149-156.
    Abstract

  24. Increased activities of cathepsin B and other lysosomal hydrolases in fibroblasts and bone tissue cultured in the presence of cysteine proteinases inhibitors.
    Montenez JP, Delaisse JM, Tulkens PM, Kishore BK
    Life Sciences (Pharmacology Letters) (1994) 55:1199-1208.
    Abstract

  25. Leupeptin and E-64, inhibitors of cysteine proteinases, prevent gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts.
    Montenez JP, Kishore BK, Maldague P, Tulkens PM
    Toxicol Lett (1994) 73:201-208.
    Abstract

  26. Once-a-day administration of amikacin in neonates: assessment of nephrotoxicity and ototoxicity.
    Langhendries JP, Battisti O, Bertrand JM, François A, Darimont J, Ibrahim S, Tulkens PM, Bernard A, Scalais E
    Dev Pharmacol Ther (1993) 20:220-230.
    Abstract

  27. Administration en dose unique journalière de l'amikacine: adaptation à la néonatologie pour des enfants traités avant le 3ème jour d'age postnatal.
    Langhendries JP, Battisti O, Betrand JM, François A, Darimont J, Tulkens PM, Bernard A, Buchet JP, Wallemacq PE
    Med Mal Infect (1993) 23 (Sp.):44-54.

  28. Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells.
    Van Bambeke F, Mingeot-Leclercq MP, Schanck A, Brasseur R, Tulkens PM
    Eur J Pharmacol (1993) 247:155-168.
    Abstract

  29. Comparative assessment of poly-L-aspartic and poly-L-glutamic acids against gentamicin-induced renal lysosomal phospholipidosis, phospholipiduria and cell proliferation in rats.
    Kishore BK, Ibrahim S, Lambricht P, Laurent G, Maldague P, Tulkens PM
    J Pharmacol Exp Ther (1992) 262:424-432.
    Abstract

  30. Accessibility of aminoglycosides, isolated and in interaction with phosphatidylinositol, to water: a conformational analysis using the concept of molecular hydrophobicity potential.
    Mingeot-Leclercq MP, Tulkens PM, Brasseur R
    Biochem Pharmacol (1992) 44:1967-1975.
    Abstract

  31. Effect of substrate organization on the activity and on the mechanism of gentamicin-induced inhibition of rat liver lysosomal phospholipase A1.
    Piret J, Kishore BK, Tulkens PM
    Biochem Pharmacol (1992) 43:895-898.
    Abstract

  32. Interactions of aminoglycosides with phosphatidylinositol: a 15N nuclear magnetic resonance study.
    Schanck A, Brasseur R, Mingeot-Leclercq MP, Tulkens PM
    Magn Reson Chem (1992) 30:11-15.

  33. Interactions of aminoglycosides with phospholipids. A deuterium Nuclear Magnetic Resonance study.
    Schanck A, Mingeot-Leclercq MP, Tulkens PM, Carrier D, Smith ICP, Jarrel HC
    Chem Phys Lipids (1992) 62:153-163.
    Abstract

  34. Empiric antimicrobial therapy with a single daily dose of ceftriaxone plus amikacin in febrilegranulocytopenic patients: a pilot study.
    Meunier F, Van der Auwera P, Aoun M, Ibrahim S, Tulkens PM
    J Antimicrob Chemother (1991) 27(C):129-139.
    Abstract

  35. New derivatives of kanamycin B obtained by modifications and substitutions in position 6". II. In vitro and computer-aided toxicological evaluation, with respect to interactions with phosphatidylinositol.
    Mingeot-Leclercq MP, Van Schepdael A, Brasseur R, Busson R, Vanderhaeghe HJ, Claes PJ, Tulkens PM
    J Med Chem (1991) 34:1476-1482.
    Abstract

  36. Distribution of epidermal growth factor in the kidneys of rats exposed to amikacin.
    Toubeau G, Nonclercq D, Zanen J, Lambricht P, Tulkens P, Heuson-Stiennon JA, Laurent G
    Kidney Int (1991) 40:691-699.
    Abstract

  37. Pharmacodynamic parameters and toxicity of netilmicin (6 mg/kg.day) given once daily or in three divided doses to cancer patients with urinary tract infection.
    Van der Auwera P, Meunier F, Ibrahim S, Kaufman L, Derde MP, Tulkens PM
    Antimicrob Agents Chemother (1991) 35:640-647.
    Abstract

  38. Synthesis, antibacterial activity and toxicological evaluation (in vitro and computer-aided) of 1-C-hydroxymethyl kanamycin B and 1-C-hydroxymethyl, 6"chlorokanamycin B.
    Van Schepdael A, Busson R, Vanderhaeghe HJ, Verbist L, Claes PJ, Mingeot-Leclercq MP, Brasseur R, Tulkens PM
    J Med Chem (1991) 34:1483-1492. Journal impact factor: ct
    Abstract --     Reprint

  39. New derivatives of kanamycin B obtained by modifications and substitutions in position 6". I. Synthesis and microbiological evaluation.
    Van Schepdael A, Delcourt J, Mulier M, Busson R, Mingeot-Leclercq MP, Tulkens PM, Claes PJ
    J Med Chem (1991) 34:1468-1475.
    Abstract

  40. Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by co-administration of poly-L-aspartic acid.
    Beauchamp D, Laurent G, Maldague P, Abid S, Kishore BK, Tulkens PM
    J Pharm Exp Ther (1990) 255:858-866.
    Abstract

  41. Increased levels of protein- and lipid-bound sialic acids in the renal cortex of rats injected with low doses of gentamicin.
    Kishore BK, Ibrahim S, Tulkens PM
    Toxicol Lett (1990) 51:59-65.
    Abstract

  42. Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro.
    Kishore BK, Kallay Z, Lambricht P, Laurent G, Tulkens PM
    J Pharmacol Exp Ther (1990) 255:867-874.
    Abstract

  43. Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids.
    Kishore BK, Lambricht P, Laurent G, Maldague P, Wagner R, Tulkens PM
    J Pharmacol Exp Ther (1990) 255:875-885.
    Abstract

  44. Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition by aminoglycoside antibiotics. I. Biochemical analysis.
    Mingeot-Leclercq MP, Piret J, Brasseur R, Tulkens PM
    Biochem Pharmacol (1990) 40:489-497.
    Abstract

  45. Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition by aminoglycoside antibiotics. II. Conformational analysis.
    Mingeot-Leclercq MP, Piret J, Tulkens PM, Brasseur R
    Biochem Pharmacol (1990) 40:499-506.
    Abstract

  46. Renal tissue injury and proliferative response after sucessive treatments with anticancer platinum derivatives and tobramycin.
    Nonclercq D, Toubeau G, Tulkens PM, Heuson-Stiennon JA, Laurent G
    Virchows Archiv B (Cell Pathol) (1990) 59:143-158.
    Abstract

  47. Ultrastructural, physico-chemical and conformational study of the interactions of gentamicin and bis(beta-diethylaminoethylether)hexestrol with negatively charged phospholipid bilayers.
    Mingeot-Leclercq MP, Schanck A, Ronveaux-Dupal MF, Deleers M, Brasseur R, Ruysschaert JM, Laurent G, Tulkens PM
    Biochem Pharmacol (1989) 38:729-741.
    Abstract

  48. Tissue injury and repair in the rat kidney after exposure to cisplatin and carboplatin.
    Nonclercq D, Toubeau G, Laurent G, Tulkens PM, Heuson-Stiennon JA
    Exp Mol Pathol (1989) 51:123-140.
    Abstract

  49. Nephrotoxic injury and renal tissue repair associated with the administration of the anticancer drugs cisplatin and carboplatin.
    Nonclercq D, Toubeau G, Laurent G, Tulkens PM, Heuson-Stiennon JA
    Micron Microscop Acta (1989) 20:51-58.

  50. Coupling products of amino acids to penicillin V and cephalothin: synthesis, and susceptibility to carboxypeptidases and lysosomal enzymes.
    Bounkhala Z, Renard C, Baurain R, Marchand-Brynaert J, Ghosez L, Tulkens PM
    J Med Chem (1988) 31:976-983.
    Abstract

  51. Tissue injury and proliferative response induced in rat kidney by cis-diamminedichlororo platinum (II).
    Laurent G, Yernaux V, Nonclercq D, Toubeau G, Maldague P, Tulkens PM, Heuson-Stiennon JA
    Virchows Archiv B (Cell Pathol) (1988) 55:129-145.
    Abstract

  52. Biochemical mechanism of aminoglycoside-induced inhibition of phosphatidylcholine hydrolysis by lysosomal phospholipases.
    Mingeot-Leclercq MP, Laurent G, Tulkens PM
    Biochem Pharmacol (1988) 37:591-599.
    Abstract

  53. Light and electron microscopic characterization of the proliferative response induced by tobramycin in rat kidney cortex.
    Nonclercq D, Toubeau G, Laurent G, Maldague P, Tulkens PM, Heuson-Stiennon JA
    Exp Mol Pathol (1988) 48:335-352.
    Abstract

  54. Safety and efficacy of aminoglycosides once-a-day: experimental data and randomized, controlled evaluation in patients suffering from pelvic inflammatory disease.
    Tulkens PM, Clerckx-Braun F, Donnez J, Ibrahim S, Kaêö,öllay Z, Jacqmin P, Lesne M, Kaufman MP, Gersdorff M
    J Drug Devel (1988) 1:71-82.

  55. Cellular uptake and subcellular distribution of roxithromycin and erythromycin in phagocytic cells.
    Carlier MB, Zenebergh A, Tulkens PM
    J Antimicrob Chemother (1987) 20(B):47-56.
    Abstract

  56. Influence of conversion of penicillin G into a basic derivative on its accumulation and subcellular localization in cultured macrophages.
    Renard C, Vanderhaeghe HG, Claes PJ, Zenebergh A, Tulkens PM
    Antimicrob Agents Chemother (1987) 31:410-416.
    Abstract

  57. Effects of gentamicin on the renal uptake of endogenous and exogenous proteins in conscious rats.
    Bernard A, Viau C, Ouled A, Tulkens P, Lauwerys R
    Toxicol Appl Pharm (1986) 84:431-438.
    Abstract

  58. Impairment of lysosome-pinocytic vesicle fusion in rat kidney proximal tubules after treatment with gentamicin at low doses.
    Giurgea-Marion L, Toubeau G, Laurent G, Heuson-Stiennon J, Tulkens PM
    Toxicol Appl Pharmacol (1986) 86:271-285.
    Abstract

  59. Hydrolysis of Pro-Ala dipeptides by lysosomal hydrolases. Models for the study of lysosomotropic amino acid prodrugs of penicillins.
    Renard C, Michel A, Tulkens PM
    J Med Chem (1986) 29:1291-1293.
    Abstract

  60. Dibekacin assay in serum by automated fluorescence polarization immunoassay (Abbott Tdx): comparison with high-performance liquid chromatography, substrate-labelled fluorescent and radioimmunoassay.
    Rollmann B, Van Der Auwera P, Tulkens PM
    J Pharm Biomed Anal (1986) 4:53-61.

  61. Tissue repair in rat kidney cortex after short treatment with aminoglycosides at low doses: a comparative biochemical and morphometric study.
    Toubeau G, Laurent G, Carlier MB, Abid S, Maldague P, Heuson-Stiennon JA, Tulkens PM
    Lab Invest (1986) 54:385-393.
    Abstract

  62. Morphological alterations in distal and collecting tubules of the rat renal cortex after aminoglycoside administration at low doses.
    Toubeau G, Maldague P, Laurent G, Vaamonde CA, Tulkens PM, Heuson-Stiennon JA
    Virchows Arch B (Cell Pathol) (1986) 51:475-485.
    Abstract

  63. Interactions of streptomycin and streptomycylamine derivatives with negatively charged lipid layers: correlation between binding, conformation of complexes and inhibition of lysosomal phospholipase activities.
    Brasseur R, Carlier MB, Laurent G, Claes PJ, Vanderhaeghe HJ, Tulkens PM, Ruysschaert JM
    Biochem Pharmacol (1985) 34:1035-1047.
    Abstract

  64. Interactions of aminoglycoside antibiotics with negatively charged lipid layers: biochemical and conformational studies.
    Brasseur R, Laurent G, Ruysschaert JM, Tulkens P
    Biochem Pharmacol (1984) 33:629-637.
    Abstract

  65. Early effects of gentamicin, tobramycin and amikacin on the human kidney.
    De Broe ME, Paulus GJ, Verpooten GA, Roels F, Buyssens N, Wedeen R, Van Hoof F, Tulkens P
    Kidney Int (1984) 25:643-652.
    Abstract

  66. Recovery of cortical phospholipidosis and necrosis after acute gentamicin loading in rats.
    Giuliano RA, Paulus GJ, Verpooten RA, Pattyn V, Pollet DE, Laurent G, Maldague P, Tulkens PM, De Broe ME
    Kidney Int (1984) 26:838-847.
    Abstract

  67. Gentamicin-induced stimulation of DNA synthesis in rat kidney cortex. Comparison between in vivo and in vitro models.
    Porter GA, Laurent G, Maldague P, Tulkens PM
    Toxicol Lett (1984) 23:205-213.
    Abstract

  68. Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies.
    Carlier MB, Laurent G, Claes PJ, Vanderhaeghe HJ, Tulkens PM
    Antimicrob Agents Chemother (1983) 23:440-449.
    Abstract

  69. Increased renal DNA synthesis in vivo after administration of low doses of gentamicin to rats.
    Laurent G, Maldague P, Carlier MB, Tulkens P
    Antimicrob Agents Chemother (1983) 24:586-593.

  70. Gentamicin nephrotoxicity in cadmium, lead and mercury pretreated rats.
    Viau C, Bernard A, Lauwerys RR, Tulkens P, Laurent G, Maldague P
    Toxicology (1983) 27:15-25.
    Abstract

  71. S 86451, a new derivative of gentamicin with reduced nephrotoxicity. Biochemical, morphological and functional studies.
    Wilmotte E, Maldague P, Tulkens P, Baumgartner R, Schmook F, Walzl H, Obenaus H
    Drugs Exp Clin Res (1983) 9:467-477.

  72. Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin.
    Laurent G, Carlier MB, Rollman B, Van Hoof F, Tulkens P
    Biochem Pharmacol (1982) 31:3861-3870.
    Abstract     - Reprint (PDF file - UCL only - copyright owned by the publisher)

  73. Analytical characterization and purification of plasma membrane from cultured hepatoma cells (HTC cells).
    Sauvage P, Lopez-Saura P, Leroy-Houyet MA, Tulkens P, Trouet A
    Biochim Biophys Acta (1981) 644:41-52.
    Abstract
  74. Comparative toxicity of aminoglycoside antibiotics towards the lysosomes in a cell culture model.
    Tulkens P, Van Hoof F
    Toxicology (1980) 17:195-199.
    Abstract

  75. Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts.
    Aubert-Tulkens G, Van Hoof F, Tulkens P
    Lab Invest (1979) 40:481-491.
    Abstract

  76. Cellular uptake and subcellular distribution of two non-steroidal anti-inflammatory drugs: indomethacin and ketoprofen.
    Blanchard JC, Schneider Y-J, Tulkens P, Trouet A
    Arch Int Pharmacod Ther (1979) 240:4-16.
    Abstract

  77. Cellular toxicity of gentamicin.
    Libert J, Ketelbant-Balasse P, Van Hoof F, Aubert-Tulkens G, Tulkens P
    Am J Ophthalmol (1979) 87:405-411.
    Abstract

  78. Fate of plasma membrane during endocytosis. I. Uptake and processing of anti-plasma membrane and control immunoglobulins by cultured fibroblasts.
    Schneider Y-J, Tulkens P, de Duve C, Trouet A
    J Cell Biol (1979) 82:449-465.
    Abstract

  79. Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents.
    Schneider Y-J, Tulkens P, de Duve C, Trouet A
    J Cell Biol (1979) 82:466-474.
    Abstract

  80. Uptake and intracellular distribution of neutral red in cultured fibroblasts.
    Bulychev A, Trouet A, Tulkens P
    Exp Cell Res (1978) 115:343-355.
    Abstract

  81. Analytical fractionation of cultured hepatoma cells (HTC cells).
    Lopez-Saura P, Trouet A, Tulkens P
    Biochim Biophys Acta (1978) 543:430-449.
    Abstract

  82. Uptake and subcellular localization of daunorubicin and adriamycin in cultured fibroblasts.
    Noël G, Peterson C, Trouet A, Tulkens P
    Eur J Cancer (1978) 14:363-368.
    Abstract

  83. The uptake and intracellular accumulation of aminoglycoside antibiotics in lysosomes of cultured rat fibroblasts.
    Tulkens P, Trouet A
    Biochem Pharmacol (1978) 27:415-424.
    Abstract     - Reprint (PDF - UCL only - copyright owned by the publisher)

  84. Nanocapsules: a new type of lysosomotropic carrier.
    Couvreur P, Tulkens P, Roland M, Trouet A, Speiser P
    FEBS Lett (1977) 84:323-326.
    Abstract

  85. Production of rabbit antibodies against active rat cathepsin B.
    Piérart-Gallois M, Trouet A, Tulkens P
    Acta Biol Med Ger (1977) 36:1887-1891.
    Abstract

  86. Analytical fractionation of homogenates from cultured rat embryo fibroblasts.
    Tulkens P, Beaufay H, Trouet A
    J Cell Biol (1974) 63:383-401.

  87. Immunological inhibition of lysosome function.
    Tulkens P, Trouet A, Van Hoof F
    Nature (London) (1970) 228:1282-1285.
    Abstract

  88. Influence of the injection of a sucrose solution on the properties of rat-liver lysosomes.
    Wattiaux R, Wattiaux-De Coninck S, Rutgeerts MJ, Tulkens P
    Nature (London) (1964) 203:757-758.

Last update: 5 Mar 2021
Corrections and additions: <tulkens@facm.ucl.ac.be>