Curricula
vitae of the members of the Unit
of Cellular and Molecular Pharmacology
Université catholique de Louvain (UCL-Bruxelles)
Louvain Drug Research Institute (Department
of Pharmaceutical Sciences)
Cellular and Molecular Pharmacology Unit
|
Françoise
Van Bambeke
Senior
Research
Associate of the Belgian Fund for Scientific Research
- PharmD,
1991
- PhD, 1995
- Agrégée de l'enseignement
supérieur, 2005
- Professor of Pharmacology,
Université catholique de Louvain
|
University
degrees
- 1991: Pharmacist (PharmD)
, Université catholique de Louvain, Belgium
- 1995: Doctor in Pharmaceutical
Sciences (PhD), Université catholique de Louvain, Belgium (Mentors:
Drs M.P. Mingeot-Leclercq and P.M. Tulkens)
- 2005: Agrégée de l'enseignement supérieur,
Université catholique de Louvain, Belgium (Mentors: Drs P.M.
Tulkens and M.P. Mingeot-Leclercq)
Scientific carreer
- 1991-1995: Junior Research
Assistant of the Fonds National belge de la Recherche Scientifique
in the group of Cellular and Molecular Pharmacology at the International Institute
of Cellular and Molecular Pathology
- 1995-2000 : successively
Research Assistant of the Fonds de Développement Scientifique
of the Université catholique de Louvain and Scientific
Research Worker of the Fonds National belge de la Recherche at the
Cellular and Molecular Pharmacology Unit of the Université catholique
de Louvain.
- In 1997, she left to
make a post-doctoral stay at the Unité des Agents antibactériens
of the Pasteur Institute in Paris (Mentor: Prof. P. Courvalin) where she trained
in molecular biology in the field of resistance to antibiotics.
- 2000-2006 : Research
Associate of the Fonds National belge de la Recherche Scientifique
at the Cellular and Molecular Pharmacology Unit of the Université catholique
de Louvain.
- 2006-up to now : Senior
Research Associate of the Fonds National belge de la Recherche Scientifique
at the Cellular and Molecular Pharmacology Unit of the Université catholique
de Louvain
Research Activities
- Cellular pharmacokinetics
of antibiotics : study of the mechanisms of penetration, accumulation, distribution,
and efflux of antibiotics in eucaryotic cells, including the study of their
transport by eucaryotic efflux pumps.
- Cellular pharmacodynamics
of antibiotics: study of the relationship between antibiotic accumulation
and activity against intracellular bacteria, and elaboration of strategies
to modulate intracellular activity (inhibition of efflux pumps, e.g.)
- Cellular toxicodynamics
of antibiotics: morphological and biochemical studies of storage disorders
induced by antibiotics will cellular tropism
- Search and pharmacological
evaluation of new antibiotics directed against new targets, either by screening
of well characterized natural sources (Mycothèque de l’UCL (http://www.mbla.ucl.ac.be/)
or by rational design and chemical synthesis.
Publications and Conferences
- List of publications
(full papers) with links to abstracts and full text: see our web
site (access to full texts for UCL only unless indicated otherwise)
- Posters or oral short
communications made at scientific meetings: see our web
site (since 2003)
- Invited lectures at scientific
meetings and seminars: see our web
site
Main teaching activities
- At the Université
catholique de Louvain (to students in pharmacy):
- Antiinfective pharmacology
and pharmacotherapy at the graduate (FARM2233)
and postgraduate level (HOPI2106)
- Pharmacology and pharmacotherapy
(partim; FARM2133)
- Pharmacotherapy (practical
lessons) as a part of Pharmacologie spéciale et éléments
de pharmacothérapie (FARM2111
and FARM2211)
- Pathologie infectieuse
(FARM
3300)
- At the Institut Paul
Lambin (to laboratory technicians; till 2004)
Educational activities in
the field of anti-infective pharmacology
- author of several educational
papers on the clinical usage of antibiotics (see 'Publications du Séminaire
de Pathologie Infectieuse')
- author of a Belgian Interuniversity
Course on Antiinfective agents (see "Syllabus interuniversitaire de Pharmacologie:
Antiinfectieux").
Member of scientific societies
- Société
belge de Biologie Cellulaire (since 1994)
- Société
belge des Sciences Pharmaceutiques (since 1995)
- Société
belge d'Infectiologie et de Microbiologie Clinique (since 1997)
- International Society
for Anti-infective Pharmacology (since 1997)
- American Society for
Microbiology (since 1999)
- European European Society
of Clinical Microbiology and Infectious Diseases (since 2008)
Activities in committees/societies
- treasurer of the the
PK/PD of Anti-Infectives
Study Group of the European Society of Clinical Microbiology and Infectious
Diseases (since 2010)
- PK/PD expert for the
Belgian National Antibiotic Committee
Member of editorial boards:
- Chemotherapy (since 2005)
- Recent patents on antiinfective
drug discovery (journal launched in 2006)
Last to update: July 2,
2011