Université Catholique de Louvain (UCL-Bruxelles)

Department of Pharmaceutical Sciences
Cellular and Molecular Pharmacology Unit (Dir. Prof. P.M. Tulkens)
Reviews, Chapters of Books, Books, or Proceedings (by reverse chronological order)
(in peer-reviewed scientific publications)
Last update: 30/12/2000
See also the indexed search or go back to the previous page for a list of our Original Papers (full papers), Abstracts, PhD Theses, Master Degree Dissertations, or Educational papers.
  1. Antibiotic efflux pumps.
    Van Bambeke F, Balzi E, Tulkens PM
    Biochem Pharmacol (2000) 60:457-470.
    Review -- Journal impact factor: 2.755 (in 1999)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  2. Aminoglycosides: nephrotoxicity.
    Mingeot-Leclercq MP, Tulkens PM
    Antimicrob Agents Chemother (1999) 43:1003-1012.
    Review -- Journal impact factor: 3.761 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  3. Aminoglycosides: activity and resistance.
    Mingeot-Leclercq MP, Glupczynski Y, Tulkens PM
    Antimicrob Agents Chemother (1999) 43:727-737.
    Review -- Journal impact factor: 3.761 (in 1998)
    Abstract -- Reprint (PDF file - UCL only - copyright owned by the publisher)

  4. Pharmacologie et pharmacothérapie anti-infectieuse. 1. Antibiotiques 2. Antifongiques 3. Antiviraux.
    Van Bambeke F, Tulkens PM
    In: Syllabus national belge de pharmacologie, A. Herchuelz ed., Presses Universitaires de Bruxelles, Belgium, pp 232 (1999)
    Book

  5. Anti-infective therapy: Mechanisms of action.
    Van Bambeke F, Lambert D, Mingeot-Leclercq MP, Tulkens PM
    In: Infectious Diseases, D. Armstrong and J. Cohen ed., Mosby, London, United Kingdom, 1.1-1.14 (1999) ISBN
    Chapter of book
    Reprint

  6. Aminoglycosides and vancomycin.
    Verpooten GA, Tulkens PM, Bennett WM
    In: Clinical nephrotoxins. Renal injury from drugs and chemicals, M.E. De Broe, G.A. Porter, W.M. Bennett & G.A. Verpooten ed., Kluwer Academic Publishers, The Netherlands, 105-120 (1998)
    Chapter of book / Proceedings

  7. Lysosomal phospholipidosis and apoptosis induced in cultured fibroblasts by aminoglycosides antibiotics and their prevention by poly-L-aspartic.
    El Mouedden M, Laurent G, Tulkens PM
    In: 4th IUBMB Conference (The cell & Death of the Cell), Edinburgh, Scotland, 14-17 (1996)
    Chapter of book / Proceedings

  8. Intracellular kinetics of antibiotics.
    Tulkens PM
    In: Pathogenesis and Management of Intracellular Bacterial Infections, J.C. Pechère ed., 21-28 (1996)
    Chapter of book / Proceedings

  9. Pharmacocinétique et pharmacodynamie intracellulaire des antibiotiques.
    Tulkens PM
    Rev Pneumol Clin (1996) 52:1-4.
    Review
    Abstract

  10. Molecular parameters involved in aminoglycosides nephrotoxicity.
    Mingeot-Leclercq M-P, Brasseur R, Schanck A
    J Toxicol Environ Health (1995) 44:263-300.
    Review -- Journal impact factor: 1.498
    Abstract

  11. Molecular description of the interactions of aminoglycoside antibiotics with negatively-charged phospholipids. Theoretical molecular modelling and experimental results.
    Mingeot-Leclercq M-P, Schanck A, Van Bambeke F, Tulkens PM, Lins L, Brasseur R
    Life Science/Advances in Pharmacology (1995) 14:71-98.
    Review -- Journal impact factor: 1.148

  12. Acute renal failure induced by aminoglycoside antibiotics: pathophysiology, clinical implications and development of protective measures.
    Kishore BK, Maldague P, Laurent G, Mingeot-Leclercq M-P, Ibrahim S, Tulkens PM
    In: Asian Nephrology - Proceedings of Fifth Asian Pacific Congress of Nephrology (1992), Sakhuja V. and Malhotra H.S. ed., Oxford University Press, New Delhi, 401-409 (1994)
    Chapter of book / Proceedings

  13. .
    Bryskier AJ, Butzler JP, Neu HC, Tulkens PM
    Macrolides: chemistry, pharmacology and clinical uses, A.J. Bryskier, J.P. Butzler, H.C. Neu and P.M. Tulkens ed., pp 743 (1993)
    Book

  14. Co-oxydextran as a protectant against gentamicin-induced renal lysosomal phospholipidosis and focal tubular necrosis: Perspectives and limitations.
    Kishore BK, Van Schepdael A, Laurent G, Lambricht P, Claes PJ, Piret J, Tulkens PM, Maldague P
    In: Contributions to Nephrology (Kidney, Proteins and Drugs), C. Bianchi, V. Bocci, F.A. Carone & R. Rabkin ed., Karger, Basel, 213-219 (1993)
    Chapter of book / Proceedings
    Abstract

  15. Influnce of the coadministration of poly-L-aspartic acid on the gentamicin-induced renal phospholipidosis, qualitative and quantitative lysosomal alterations and cell turnover in rat kidney cortex.
    Kishore BK, Ibrahim S, Lambricht P, Laurent G, Maldague P, Tulkens PM
    Renal Failure (1992) 14:120.
    Chapter of book / Proceedings

  16. Lysosomal storage disorders and toxicity induced by aminoglycoside antibiotics and polyanionic peptides.
    Kishore BK, Maldague P, Tulkens PM
    In: Endocytosis: From Cell Biology to Health, Disease and Therapy (NATO ASI Series), P. J. Courtoy ed., Springer Verlag, Berlin, 439-446 (1992)
    Chapter of book / Proceedings

  17. Effect of the schedule of administration of two aminoglycosides, netilmicin and amikacin on urinary phospholipid excretion in humans.
    Ibrahim S, Clerckx-Braun F, Jacqmin Ph, Donnez J, Brulein V, Tulkens PM
    In: Nephrotoxicity: Mechanims, Early Diagnosis and Therapeutic Management., P.H. Bach, N.J. Gregg, M.F. Wilks and L. Delacruz ed., Marcel Dekker, New York, 93-97 (1991)
    Chapter of book / Proceedings

  18. Effect of aminoglycosides and of coadministration of poly-L-aspartic acid on urinary phsopholipids excretion: a comparative Study.
    Ibrahim S, Kishore BK, Lambricht P, Laurent G, Tulkens PM
    In: Nephrotoxicity: Mechanisms, Early Diagnosis and Therapeutic Management, P.H. Bach, N.J. Gregg, M.F. Wilks and L. Delacruzz ed., Marcel Dekker, New York, 105-109 (1991)
    Chapter of book / Proceedings

  19. Morphological evidence of nephrotoxicity of poly-D-glutamic acid in rats.
    Maldague P, Kishore BK, Lambricht P, Ibrahim S, Laurent G, Tulkens PM
    In: Nephrotoxicity: Mechanisms, Early Diagnosis, and Therapeutic Management, P.H. Bach, N.J. Gregg, M.F. Wilks and L. Delacruz ed., Marcel Dekker, Inc. New York., 131-136 (1991)
    Chapter of book / Proceedings

  20. Aminoglycosides nephrotoxicity.
    Mingeot-Leclercq MP, Laurent G, Kishore BK, Tulkens PM
    Life Sc Adv (Biochem Pharmacol) (1991) 10:113-141.
    Review

  21. Intracellular distribution and activity of antibiotics.
    Tulkens PM
    Eur J Clin Microbiol Infect Dis (1991) 10:100-106.
    Review
    Abstract     - Reprint (PDF file - UCL only - copyright owned by the publisher)

  22. Pharmacokinetic and toxicological evaluation of the once-daily regimen versus conventional schedules of netilmicin and amikacin.
    Tulkens PM
    J Antimicrob Chemother (1991) 27:49-61.
    Review
    Abstract

  23. Target drugs for the treatment of intracellular infections.
    Tulkens PM
    Flem Vet J (1991) Suppl. 1:163-168.
    Chapter of book / Proceedings

  24. Cellular uptake, localization and activity of fluoroquinolones in uninfected and infected macrophages.
    Carlier MB, Scorneaux B, Zenebergh A, Desnottes JF, Tulkens PM
    J Antimicrob Chemother (1990) 26(B):27-39.
    Chapter of book / Proceedings
    Abstract     | Reprint (PDF)

  25. Safety, pharmacokinetics and efficacy of once-a-day administration of netilmicin and amikacin versus their conventional schedules in patients suffering from pelvic inflammatory disease.
    Ibrahim S, Derde MP, Kaufman L, Clerckx-Braun F, Jacqmin Ph, Brulein V, Donnez J, Tulkens PM
    Renal Failure (1990) 12:199-203.
    Chapter of book / Proceedings
    Abstract

  26. Inhibition of aminoglycoside-induced nephrotoxicity in rats by polyanionic peptides.
    Kishore KB, Lambricht P, Ibrahim S, Laurent G, Tulkens PM, Maldague P
    In: Contribution to Nephrology (Kidney, Proteins and Drugs), C. Bianchi, Bocci V., Carone F.A., Rabkin, R. ed., Karger, Basel, 191-201 (1990)
    Chapter of book / Proceedings

  27. Aminoglycosides once-a-day in pelvic inflammatory disease.
    Lambricht P, Clerckx-Braun F, Smets M, Leal T, Delmée M, Tulkens PM, Donnez J
    In: Proceed. 2d Intern. Meeting of the European Society for Infectious Diseases in Gynecology and Obstetrics, Guaschino, S. ed., Monduzzi Editore, Bologna, 381-387 (1990)
    Chapter of book / Proceedings

  28. Aminoglycoside-induced phospholipidosis and nephrotoxicity.
    Laurent G, Kishore BK, Tulkens PM
    Biochem Pharmacol (1990) 40:2383-2392.
    Review
    Abstract

  29. Efficacy and safety of aminoglycosides once-a-day: experimental and clinical data.
    Tulkens PM
    Scand J Infect Dis (1990) Suppl. 74:249-257.
    Review
    Abstract

  30. The intracellular pharmacokinetics and activity of antibiotics.
    Tulkens PM
    In: Frontiers of Infectious Diseases: New Antibacterial Strategies, H.C. Neu ed., Churchill Livingstone/Longman Group, Edinburgh, 243-259 (1990)
    Chapter of book / Proceedings

  31. Intracellular pharmacokinetics and localization of antibiotics as predictors of their efficacy against intraphagocytic infections.
    Tulkens PM
    Scand J Infect Dis (1990) Suppl. 74:209-217.
    Review
    Abstract

  32. Accumulation and subcellular distribution of antibiotics in macrophages in relation to activity against intracellular bacteria.
    Tulkens PM
    In: Ciprofloxacin in Pneumology, R.J. Fass ed., Zuckswerdt Verlag, München, 12-22 (1990)
    Chapter of book / Proceedings

  33. Conformational and biochemical analysis of the interactions between phospholipids and aminoglycoside antibiotics in relation with their toxicity.
    Tulkens PM, Mingeot-Leclercq MP, Laurent G, Brasseur R
    In: Molecular description of biological membrane components by computer-aided conformational analysis, R. Brasseur ed., CRC Press, Inc., Boca Raton, Fla., 63-93 (1990) ISBN 978-0849363757
    Chapter of book / Proceedings

  34. Renal phospholipidosis in rats after gentamicin and pefloxacin co-administration at low doses.
    Carlier MB, Kaêö,öllay Z, Tulkens PM
    In: Nephrotoxicity: Extrapolation from in vitro to in vivo, and animals to man, P.H. Bach & E.A.Lock ed., Plenum Press, London, 221-225 (1989)
    Chapter of book / ProceedingsJournal impact factor: ct

  35. Urinary phospholipids patterns after treatment with aminoglycoside antibiotics and cis-platinum.
    Ibrahim S, Kallay Z, Clerckx-Braun F, Donnez J, Tulkens PM, Jacqmin Ph
    In: Nephrotoxicity: Extrapolation from in vitro to in vivo, and animals to man, P.H. Bach & E.A. Lock ed., Plenum Press, London, 177-182 (1989)
    Chapter of book / Proceedings

  36. Effect of netilmicin and amikacin on urinary phospholipid excretion in humans.
    Ibrahim S, Van der Auwera P, Meunier F, Tulkens PM
    Arch Toxicol (1989) Suppl. 13:413-416.
    Chapter of book / Proceedings
    Abstract

  37. Uptake and subcellular distribution of poly-L-aspartic acid, a protectant against aminoglycoside-induced nephrotoxicity, in rat kidney cortex.
    Kallay Z, Tulkens PM
    In: Nephrotoxicity: extrapolation from in vitro to in vivo, and animals to man, P.H. Bach and E.A. Lock ed., Plenum Press, London, United Kindgom, 189-192 (1989)
    Chapter of book / Proceedings

  38. Comparative uptake and lysosomal phospholipidosis induced by gentamicin components C1, C1a, and C2.
    Kallay Z, Carlier MB, Rollmann B, Maldague P, Tulkens PM
    In: Nephrotoxicity: Extrapolation from In Vitro to In Vivo, and Animals to Man, P.H. Bach & E.A. Lock ed., Plenum Press, London, 183-188 (1989)
    Chapter of book / Proceedings

  39. Aminoglycoside nephrotoxicity in obstructive jaundice: possible contribution by concomitantly administered corticosteroids (letter to the Editor).
    Kishore BK
    Am J Med (1989) 87:245-246.
    Letter to Editor / Editorial
    Abstract

  40. Comparative assessment of poly-L-aspartic and poly-L-glutamic acids as protectants against aminoglycoside-induced nephrotoxicity.
    Kishore BK, Tulkens PM
    Arch Toxicol (1989) Suppl. 13:409-412.
    Chapter of book / Proceedings

  41. Clinico-biochemical aspects of guanidine compounds in uraemic toxicity.
    Kishore BK, Kaêö,öllay Z, Tulkens PM
    Int Urol Nephrol (1989) 21:223-232.
    Review
    Abstract

  42. Is malondialdehyde a putative uremic toxin?.
    Kishore KB
    Nepron (1989) 52:286.
    Letter to Editor / Editorial
    Abstract

  43. Nephrotoxicity of aminoglycosides.
    Tulkens PM
    Toxicol Lett (1989) 46:107-123.
    Review
    Abstract

  44. In vitro study and conformational analysis of 1-N-aminohydroxybutyryl derivatives of aminoglycosides in correlation with their inhibitory potency towards lysosomal phospholipases.
    Carlier MB, Brasseur R, Ruysschaert JM, Tulkens PM
    Arch Toxicol (1988) Suppl.12:186-189.
    Chapter of book / Proceedings

  45. Interaction of diphtheria toxin (fragment B) with natural membranes.
    Falmagne P, Wattiez R, Cabiaux V, Phalipon A, Kaczorek M, Tulkens PM, Ruysschaert JM
    In: Bacterial Protein Toxins (Zbl. Bakt. Suppl. 17), Fehrenbach ed., G. Fisher Verlag, Stuttgart, 277-285 (1988)
    Chapter of book / Proceedings

  46. Individualisation de la posologie basée sur les paramètres de populations: application aux aminoglycosides.
    Jacqmin Ph, Ponchaut S, Brulein V, Clerckx-Braun F, De Baecker M, Donnez J, Moulin D, Reynaert M, Tulkens PM
    In: Intérêt et Limites de la Pharmacocinétique en Recherche et Développement, J. Bres & G. Panis ed., Sauramps Médical (Diffusion Vigot), Paris, France, 128-137 (1988)
    Chapter of book / Proceedings

  47. Kidney tissue repair after nephrotoxic injury : biochemical and morphological characterization.
    Laurent G, Toubeau G, Heuson-Stiennon JA, Tulkens P, Maldague P
    CRC Crit Rev Toxicol (1988) 19:147-183.
    Review
    Abstract

  48. Antibiotic-induced nephrotoxicity.
    Tulkens PM
    In: International Workshop on the Health Significance of Nephrotoxicity, Commission of the European Communities/World Health Organization, 131-167 (1988)
    Review

  49. Mode of nephrotoxicity of aminoglycosides, and animal and human experience with once-daily regimen.
    Tulkens PM
    In: Proceedings of The International Symposium on Netilmicin, Y. Ueda ed., Professional Postgraduate Services, K.K., Tokyo, 49-62 (1988)
    Chapter of book / Proceedings

  50. Reduction of aminoglycoside-induced renal alterations in rats by coadministration of piperacillin at clinically-relevant doses.
    Carlier MB, Kaêö,öllay Z, Rollmann B, Tulkens PM
    In: Progress in Antimicrobial and Anticancer Chemotherapy, B. Berkarda & H.-P. Kuemmerle ed., Ecomed Verlag, Landsberg/Lech, W. Germany, 873-875 (1987)
    Chapter of book / Proceedings

  51. Handling of two macrolides, erythromycin and roxithromycin (RU 28965) by human and animal macrophages in culture.
    Carlier MB, Zenebergh A, Tulkens PM
    In: Progress in Antimicrobial and Anticancer Chemotherapy, B. Berkarda & H.-P. Kuemmerle ed., Ecomed Verlag, Landsberg/Lech, W. Germany, 569-571 (1987)
    Chapter of book / Proceedings

  52. Aminoglycoside nephrotoxicity: cellular and molecular aspects.
    Laurent G, Tulkens PM
    In: ISI Atlas of Science: Pharmacology, Waverly Press, Baltimore, 40-44 (1987)
    Review

  53. Uptake and intracellular distribution of 2 fluoroquinolones, pefloxacin and ciprofloxacin, in phagocytes.
    Zenebergh A, Carlier MB, Scorneaux B, Tulkens PM
    In: Progress in Antimicrobial and Anticancer Chemotherapy, B. Berkarda & H.-P. Kuemmerle ed., Ecomed Verlag, Landsberg/Lech, W. Germany, 1906-1908 (1987)
    Chapter of book / Proceedings

  54. Reduction of gentamicin nephrotoxicity by the concomitant administration of poly-L-aspartic acid and poly-L-asparagine in rats.
    Beauchamp D, Laurent G, Maldague P, Tulkens PM
    Arch Toxicol (1986) suppl.9:306-309.
    Chapter of book / Proceedings
    Abstract

  55. Use of an in vitro model to assess aminoglycoside-phospholipid interactions in relation to their nephrotoxicity.
    Carlier MB, Brasseur R, Laurent G, Mingeot-Leclercq MP, Ruysschaert JM, Tulkens PM
    Fd Chem Toxicol (1986) 24:815-816.
    Chapter of book / Proceedings

  56. Animal study on the nephrotoxic potential of gentamicin-ceftazidime combination treatment at low doses.
    Carlier MB, Laurent G, Beauchamp D, Maldague P, Rollmann B, Tulkens PM
    In: Recent Advances in Chemotherapy, J. Ishigami ed., University of Tokyo Press, Tokyo, 2645-2646 (1986)
    Chapter of book / Proceedings

  57. Effect of hydroxylation of the 2',6' diaminohexose moiety on the intrarenal accumulation of aminoglycoside antibiotics: comparison between kanamycin B, tobramycin, dibekacin and gentamicin.
    Giurgea-Marion L, Tulkens PM
    In: Recent Advances in Chemotherapy, J. Ishigami ed., University of Tokyo Press, Tokyo, 2679-2680 (1986)
    Chapter of book / Proceedings

  58. Accumulation and subcellular localization of a basic derivative of Penicillin G in J774 macrophages.
    Renard C, Zenebergh A, Vanderhaeghe HJ, Claes PJ, Tulkens PM
    In: Recent Advances in Chemotherapy, J. Ishigami ed., University of Tokyo Press, Tokyo, 331-332 (1986)
    Chapter of book / Proceedings

  59. Experimental studies on nephrotoxicity of aminoglycosides at low doses: mechanisms and perspectives.
    Tulkens PM
    Am J Med (1986) 80:105-114.
    Review
    Abstract

  60. Kidney phospholipidosis and recovery after acute exposure to gentamicin with low and high doses in an infused rat model.
    Giuliano RA, Paulus GJ, Verpooten GA, Pattijn VM, Pollet DE, Nouwen EJ, De Broe ME
    In: Renal Heterogeneity and Target Cell Toxicity, P.H. Bach & E.A. Lock ed., J. Wiley & Sons, Pub., London (U.K.), 323-326 (1985)
    Chapter of book / Proceedings

  61. Buoyant and functional alterations of lysosomes of proximal tubular cells after treatment with gentamicin : biochemical and morphological studies.
    Giurgea-Marion L, Laurent G, Toubeau G, Heuson-Stiennon J, Beauchamp D, Carlier MB, Tulkens P
    In: Renal Heterogeneity and Target Cell Toxicity, P.H. Bach & E.A. Lock ed., J. Wiley & Sons, Pub., London, 357-360 (1985)
    Chapter of book / Proceedings

  62. The design of antibiotics capable of an intracellular action: aims, potentialities and problems.
    Tulkens PM
    In: Drug Targeting, P. Buri & A. Gumma ed., Elsevier Science Publishers, B.V., Amsterdam, 179-193 (1985)
    Chapter of book / Proceedings

  63. In vitro model and semi-empirical conformational analysis to study and compare the intrinsic nephrotoxicity of aminoglycoside antibiotics.
    Tulkens PM, Laurent G, Carlier MB, Lambricht P, Mingeot-Leclercq MP, Ruysschaert JM
    In: Recent advances in Chemotherapy, J. Ishigami ed., University of Tokyo Press, Tokyo, 2634-2635 (1985)
    Chapter of book / Proceedings

  64. Computer models and structure-activity data for the prediction of aminoglycoside-induced nephrotoxicity.
    Tulkens PM, Ruysschaert JM, Brasseur R, Carlier MB, Laurent G, Claes JP, Vanderhaeghe HJ
    In: Renal Heterogeneity and Target Cell Toxicity, P.H. Bach and E.A. Lock ed., J. Wiley & Sons, Pub., London, 303-313 (1985)
    Chapter of book / Proceedings

  65. Polycationic gentamicin inhibits the tubular reabsorption of plasma proteins according to their electrical charges.
    Viau C, Bernard A, Ouled A, Lauwerys R, Tulkens P
    In: Renal Heterogeneity and Target Cell Toxicity, P.H. Bach & E.A. Lock ed., J. Wiley & Sons, Pub., London, 353-356 (1985)
    Chapter of book / Proceedings

  66. Subcellular localization of clindamycin in J774 macrophages, peritoneal macrophages and fibroblasts compared to two lysosomotropic amines: chloroquine and dimethylaminopropylpenicillinamide.
    Zenebergh A, Renard C, Tulkens PM
    In: Recent Advances in Chemotherapy, J. Ishigami ed., University of Tokyo Press, Tokyo, 732-733 (1985)
    Chapter of book / Proceedings

  67. In vitro inhibition of lysosomal phospholipases by aminoglycoside antibiotics: a comparative study.
    Carlier MB, Laurent G, Tulkens P
    Arch Toxicol (1984) 7(suppl.):282-285.
    Chapter of book / Proceedings
    Abstract

  68. Tubular regeneration in rat kidney cortex during treatment with gentamicin at a low dose..
    Laurent G, Toubeau G, Maldague P, Carlier MB, Heuson-Stiennon J, Tulkens P
    Arch Toxicol (1984) 7(suppl.):459-463.
    Chapter of book / Proceedings
    Abstract

  69. A 2'guanidyl derivative of gentamicin (S86451) with reduced nephrotoxicity : studies at low and medium dose levels in the rat.
    Maldague P, Laurent G, Carlier MB, Tulkens P
    Arch Toxicol (1984) 7(suppl.):455-458.
    Chapter of book / Proceedings
    Abstract

  70. Aminoglycosides nephrotoxicity: recent insights and perspectives.
    Tulkens P
    In: Contributions to Nephrology. Kidney, small molecules and drugs, C. Bianchi, A. Bertelli & G.C. Duarte ed., Karger, A.G., Pub., Basel, 168-181 (1984)
    Chapter of book / Proceedings

  71. Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro studies.
    Carlier MB, Laurent G, Claes PJ, Vanderhaeghe HJ, Tulkens PM
    In: Proceedings of the 13th International Congress of Chemotherapy, Vienna, K.H. Spitzy & K. Karrer ed., 62-65 (1983)
    Chapter of book / Proceedings

  72. Early toxicity of aminoglycosides in human kidney: a prospective, comparative study of amikacin, gentamicin, netilmicin and tobramycin.
    De Broe ME, Paulus GJ, Verpooten GA, Giuliano RA, Roels F, Tulkens PM
    In: Proceedings of the 13th International Congress of Chemotherapy, Vienna, K.H. Spitzy & K. Karrer ed., 11-24 (1983)
    Chapter of book / Proceedings

  73. Comparative nephrotoxicity of four aminoglycosides : biochemical and ultrastructural modifications of lysosomes.
    Fillastre JP, Hemet J, Tulkens P, Morin JP, Viotte G, Ollier B, Godin M
    In: Advances in Nephrology, J. Hamburger, J. Crosnier, J.P. Grunfeld & M. Maxwell ed., Year Book Med. Pub., Chicago, Ill, 253-275 (1983)
    Chapter of book / Proceedings

  74. Uptake and distribution of TDM 85530 in mouse macrophages and rat fibroblasts.
    Tatzber F, Lam C, Zenebergh A, Schuster I, Tulkens P
    In: Proceedings of the 13th International Congress of Chemotherapy, Vienna, K.H. Spitzy & K. Karrer ed., 15-19 (1983)
    Chapter of book / Proceedings

  75. Comparative study of the alterations induced in rat kidney by gentamicin, dibekacin, netilmicin, tobramycin and amikacin at low doses.
    Tulkens P, Laurent G, Carlier MB, Toubeau G, Heuson-Stiennon J, Maldague P
    In: Proceedings of the 13th International Congress of Chemotherapy, Vienna, K.H. Spitzy and K. Karrer ed., 30-35 (1983)
    Chapter of book / Proceedings

  76. Lysosomal alterations in aminoglycoside-induced acute renal failure.
    Tulkens PM, De Broe ME, Maldague P, Heuson-Stiennon JA
    In: Acute renal failure: correlations between morphology and function, K. Solez & A. Whelton ed., Marcel Dekker Pub., New York, 299-327 (1983)
    Chapter of book / Proceedings

  77. Early toxic events in kidney of rat and man following administration of gentamicin at low doses.
    Carlier MB, Paulus G, Maldague P, Giurgea L, Wilmotte E, de Broe ME, Tulkens P
    Arch Toxicol (1982) 5:287-290.
    Chapter of book / Proceedings
    Abstract

  78. Nephrotoxicity of gentamicin in humans..
    De Broe ME, Paulus GJ, Verpooten GA, Roels F, De Prest B, Van Hoof F, Buyssens N
    In: Néphrotoxicité et ototoxicité médicamenteuses/Nephrotoxicity and ototoxicity of drugs, J.P. Fillastre ed., Editions INSERM et Publications de l'Universit{ de Rouen, France, 147-165 (1982)
    Chapter of book / Proceedings

  79. Nephrotoxicity of aminoglycosides : experimental data and clinical implications.
    De Broe ME, Verpooten GA, Giuliano RA, Paulus GJ, Pollet DE, Laurent G, Tulkens PM
    In: Controversial aspects of aminoglycoside therapy, J. Klastersky ed., Europrint 2000, Brussels, 35-45 (1982)
    Chapter of book / Proceedings

  80. Etude comparative de la néphrotoxicité de quatre aminoglycosides: modifications biochimiques et ultrastructurales lysosomiales.
    Fillastre JP, Hemet J, Morin JP, Tulkens P, Viotte G, Olier B, Godin M
    In: Actualités Néphrologiques de l'Hôpital Necker, 91-109 (1982)
    Chapter of book / Proceedings

  81. Comparative nephrotoxicity of gentamicin, netilmicin, tobramycin and amikacin in rats.
    Ollier B, Morin JP, Viotte G, Tulkens P, Van Hoof F, Fillastre JP
    In: Current Chemotherapy and Immunotherapy, P. Periti and G. Gialdroni-Grassi ed., Am. Soc. Microbiol. Pub., Washington DC, 839-841 (1982)
    Chapter of book / Proceedings

  82. The lysosomal toxicity of gentamicin: a short review.
    Tulkens P
    In: Néphrotoxicité et ototoxicité médicamenteuses/nephrotoxicity and ototoxicity of drugs, J.P. Fillastre ed., Editions INSERM et Publications de l'Université de Rouen, Rouen, France, 435-443 (1982)
    Chapter of book / Proceedings

  83. Prospective comparative study of the nephrotoxicity of aminoglycosides in human.
    De Broe ME, Paulus G, Verpooten GA, Roels F, Van Hoof F, Tulkens P
    J Antimicrob Chemother (1981) 8(suppl A):111-113.
    Chapter of book / Proceedings
    Abstract

  84. Intracellular penetration and distribution of antibiotics: the basis for an improved chemotherapy of intracellular infectious.
    Trouet A, Tulkens P
    In: The future of antibiotherapy and antibiotic research, L. Ninet, P.E. Bost, D.H. Bouanchaud, J. Florent ed., Academic Press, London, 337-349 (1981)
    Chapter of book / Proceedings

  85. Lysosomal toxicity of gentamicin in rat kidney and comparisons with amikacin and tobramycin.
    Tulkens P, Carlier MB, Morin JP, Beauwens R, Maldague P, Giurgea L, Van Hoof F
    In: Current Chemotherapy and Immunotherapy, P. Periti and G. Gialdroni-Grassi ed., Am. Soc. Microbiol. Pub., Washington DC, 850-852 (1981)
    Chapter of book / Proceedings

  86. The renal toxicity of aminoglycoside antibiotics: mechanism and comparisons between gentamicin, netilmicin, tobramycin and amikacin..
    Tulkens P, Morin JP, Carlier MB, Van Hoof F, Hallynck Th, Pijck J
    In: Current concepts in microbiology, A. Adam, P. Ers and J. Pijck ed., Elsevier/North Holland Biomed. Press, Amsterdam, 83-103 (1981)
    Chapter of book / Proceedings

  87. Early morphological and biochemical events related to gentamicin nephrotoxicity.
    Morin JP, Van Hoof F, Tulkens P, Fillastre JP
    In: Current chemotherapy and infectious diseases, J.D. Nelson and Carlo Grassi ed., Amer. Soc. Microbiol., Washington DC, 610-612 (1980)
    Chapter of book / Proceedings

  88. Gentamicin-induced nephrotoxicity: a cell biology approach.
    Morin JP, Viotte G, Vandewalle A, Van Hoof F, Tulkens P, Fillastre JP
    Kidney Int (1980) 18:583-590.
    Review
    Abstract

  89. Subcellular localization of infectious agents: pharmacological and pharmacokinetic implications.
    Trouet A, Tulkens P, Schneider Y-J
    In: The host invader interplay, H. Vanden Bossche ed., Janssen Research Foundation, Elsevier/North Holland Biomedical Press, Amsterdam, 31-44 (1980)
    Chapter of book / ProceedingsJournal impact factor: ct

  90. Membrane recycling (shuttle ?) in endocytosis.
    Tulkens P, Schneider Y-J, Trouet A
    In: Mononuclear phagocytes : functional aspects, R. van Furth ed., M. Nijhoff Pub., The Hague, 613-647 (1980)
    Chapter of book / Proceedings

  91. Nanokapseln: ein neuer lysosomotropischer Trager.
    Couvreur P, Roland M, Speiser P, Trouet A, Tulkens P
    Acta Pharmaceutica Technologica (APV Informations (1979) 7spl:185-188.
    Chapter of book / Proceedings

  92. Cellular pharmacology and toxicology: a tool for the evaluation and design of drugs.
    Tulkens P, Trouet A
    Acta Therapeutica (1979) 5:111-126.
    Chapter of book / Proceedings

  93. The intralysosomal pH.
    de Duve C, Okhuma S, Poole B, Tulkens P
    In: Microenvironments and metabolic Compartmentation, Srere, P.A. and Eastabrook, R.W. ed., Academic Press, New York, 371-380 (1978)
    Chapter of book / Proceedings

  94. Recycling of membranes during endocytosis.
    Schneider Y-J, Tulkens PM, Trouet A
    In: Transport of Macromolecules in Cellular Systems, S.C. Silverstein ed., Dahlem Konferenzen-Berlin, Abakon Verlag-gesell, Berlin W., 181-196 (1978)
    Chapter of book / Proceedings

  95. The lysosomal toxicity of aminoglycosides.
    Tulkens P, Aubert-Tulkens G, Van Hoof F, Trouet A
    In: Nephrotoxicity: interaction of drugs with membrane systems : Mitochondria-Lysosomes, J.P. Fillastre ed., Publications de l'Université de Rouen, Rouen, France, and Masson Pub. U.S.A. Inc., New York, N.Y., 231-251 (1978)
    Chapter of book / Proceedings

  96. A shuttle between cell surface and lysosomes during endocytosis.
    Tulkens P, Schneider Y-J, Trouet A
    In: Protein Turnover and Lysosome Function, H. Segal and D. Doyle ed., Academic Press, New York, 719-738 (1978)
    Chapter of book / Proceedings

  97. Recycling of fibroblast plasma membrane antigens internalized during endocytosis.
    Schneider Y-J, Tulkens P, Trouet A
    Biochem Soc Transact (1977) 5:1164-1167.
    Chapter of book / Proceedings
    Abstract

  98. Etude du mécanisme d'endocytose à l'aide d'anticorps spécifiques.
    Schneider Y-J, Tulkens P, Trouet A
    Ann Sci Nat Bot Biol (1977) 18:61-69.
    Chapter of book / Proceedings

  99. The fate of plasma the plasma membrane during endocytosis.
    Tulkens P, Schneider Y-J, Trouet A
    Biochem Soc Transact (1977) 5:1809-1815.
    Review
    Abstract

  100. Studies on the mechanism of endocytosis in fibroblasts with the use of specific antibodies.
    Tulkens P, Schneider Y-J, Trouet A
    In: Intracellular protein catabolism II, V. Turk and N. Marks ed., J. Stefan Institute, Ljubljana and Plenum Press, New York, 73-84 (1977)
    Chapter of book / Proceedings

  101. Flow and shuttle of plasma membrane during endocytosis.
    Tulkens P, Schneider Y-J, Trouet A
    Acta Biol Med Ger (1977) 36:1681-1690.
    Chapter of book / Proceedings
    Abstract

  102. Lysosomotropic drugs: biological and therapeutical aspects.
    Tulkens P, Trouet A
    In: Membranes and diseases, L. Bolis, J.F. Hoffman and A. Leaf ed., Raven Press, New York, 131-144 (1976)
    Chapter of book / Proceedings
    Abstract

  103. Comparative cell pharmacokinetics of daunorubicin and adriamycin.
    Noël G, Trouet A, Zenebergh A, Tulkens P
    Adriamycin review (1975) 2:99-105.
    Chapter of book / Proceedings

  104. Lysosomotropic agents.
    de Duve C, de Barsy Th, Poole B, Trouet A, Tulkens P, Van Hoof F
    Biochem Pharmacol (1974) 23:2495-2531.
    Review
    Abstract

  105. Uptake and intracellular fate of anti-lysosome and anti-plasma membrane antibodies in cultured rat fibroblasts.
    Trouet A, Tulkens P, Schneider YJ
    In: Enzyme therapy in lysosomal storage diseases, J.M. Tager, C.J.M. Hooghwinkel & W. Th. Daems ed., North Holland Publ. Co., Amsterdam, 187-193 (1974)
    Chapter of book / Proceedings

  106. Effects of anti-lysosome serum on cultured fibroblasts.
    Tulkens P
    In: Methodological developments in biochemistry, E. Reid ed., Longman, London, 327-338 (1974)
    Chapter of book / Proceedings

Last update: 30/12/2000
Corrections and additions: <tulkens@facm.ucl.ac.be>