SAR of pharmacokinetic parameters

N

X

8

COOH

O

R

5

F

R

7

R

1

N

Vd

Biodisponibility

t1/2

Bulky

substituant

cipro

grepa

gati

gemi

moxi

gemi, trova

flero, peflo, oflo,

grepa, gati,

trova, moxi, gemi

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