Pseudomonas and quinolone efflux

1 Zhang et al. JAC (2001) 48: 549-552

2 Lomovskaya et al. AAC (2001)5: 105-116

CIP1 LVX2 MXF1

AB CD EF

0.1 0.125 0.8

0.4 2 3.2

0.8 2 6.4

1.6 4 12.8

Overexpressed

Mex pumps

MICs