ISAP in action in science and clinics

Some achievements:

• once-daily dosing of aminoglycosides  registration or reregistration in several countries
  • amikacin, netilmicin (from bid to qd)
  • isepamicin (registered essentially for qd dosing) 

• AUIC / MIC and Cmax / MIC ratios used as guides for phase II / III trials, for treatment optimization and for registration of fluoroquinolones
  • trovafloxacin
  • moxifloxacin

• beta-lactam continuous infusion brought to clinical trials

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