Not all fluoroquinolones are subject to active efflux ...

Influence of

probenecid * on

ciprofloxacin and

moxifloxacin accumulation in

J774 macrophages

* inhibitor of FQ efflux Cao et al., 1992

Probenecid 5 mM

(-)

(+)

Michot et al., ICAAC 2000