Rat Adjuvant Arthritis Model

B

B

B

B

B

B

B

B

J

J

J

J

J

1

1.5

2

2.5

3

3.5

0

4

8

12

16

20

24

Paw Volume (ml)

Normal

Adjuvant

B

B

B

B

B

B

B

B

B

0

20

40

60

80

100

0

4

8

12

16

20

24

PGE2 (ng/gram)

Day After Adjuvant Injection

J

J

J

Adjuvant

PG ProductionT-Cell/Monocyte InfiltratePaw SwellingJoint Destruction

CFA

CFA = Complete Freund’s Adjuvant

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