Categories of COX Inhibitors

1. COX-1 specific Low dose aspirin

2. COX non-specific All current NSAIDs

3. COX-2 preferential* Agent with some anti-inflammatory or analgesic activities at a dose that inhibits COX-2 but causes no significant inhibition of COX-1

4. COX-2 specific Agent which at maximal therapeutic dosing causes no clinically meaningful inhibition of COX-1

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