IMPAIRMENT OF LYSOSOME - PINOCYTIC VESICLE FUSION

From Giurgea-Marion et al, Tox. Appl. Pharmacol. 86: 271-285 (1986)

Morphometry of lysosomes in PTC after cytochemical demonstration of HRP

Treatment (9 days) % cytoplasmic volume

L + L - M + M -

(a) control 2.77 ± 0.58 2.03 ± 0.47 - -

(b) Genta (10 mg/kg.day) 0.34 ± 0.17 1.16 ± 0.47 0.11 4.16 ± 0.32

X 21,500

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