Effet de Bcl-2 sur l’apoptose induite par la gentamicine a
bcl-2 (+) transfectants b bcl-2 (-) transfectants c
a cells were exposed to gentamicin (2 mM) for 4 days
b cells transfected with a bcl-2 gene-containing vector
c cells transfected with a control vector
+ significantly lower than the bcl-2 (-) group (p ɘ.001)
§ not significantly different from untransfected cells not exposed to gentamicin
MDCK-cells 3.3 ± 1.0 +,§ 21.0 ± 5.2
LLC-PK1-cells 5.4 ± 2.9 +,§ 22.9 ± 1.3