Université Catholique de Louvain (UCL-Bruxelles)
Louvain Drug Research Institute (Department of Pharmaceutical Sciences)
Cellular and Molecular Pharmacology Unit 

The first industrial patent (known in Europe) was awarded in 1421 in Florence to the Engineer Filippo Brunelleschi, who obtained it for an invention related to the handling of merchandises intended for boat transport ...

Brunelleschi was also painter, goldsmith, and architect of the Florentine school. He built the world-known "Dome of Florence" (Duomo dalla Basilica Santa Maria del Fiore). The sculpture shown above represents him while raising eyes to his work...


Awarded | Submitted


  1. Fontaine L, Lardinois A., Chalhoub H., Van Bambeke F. Ruiz-Sorribas A
    Para-pharmaceutical or pharmaceutical composition administrable to a living being, preferably a human being, comprising at least one enzyme for the treatment and/or prevention of bacterial infections involving biofilm formation

    Patent number WO/2022/079315 - date of publication: 21 April 2022
    Priority data: 2020/5726 16.10.2020 BE
    Full text - link to original document

  2. Brans A, Joris B, Delmarcelle M, Marchand J, Tulkens P, Hamaaecher C, Goormaghtigh E, De Coninck J
    Method for measuring beta-lactam antibiotics
    Patent number WO2013/053953 (A1) - Date of publication: 18 avril 2013.
    Classification: international: GOIN 33194 (2006.01) C12N 9186 (2006.01)
    Priority Data: PCT/EP2012/070434 15 October 2012 (l5.l0.20l2) and 14 October 2011 (14.I0.2011) EP
    Full text - link to original document

  3. Marchand J, Tulkens PM, Goormaghtigh E, De Coninck J, Joris B, Carryn S
    Vancomycin analysis
    Patent no. EP 2 490 029 A1 (European); Application no. 11154652.9; Date of publication:22-08-2012 Bulletin 2012/34
    Patent number WO2012/110593A1 Application number: PCT/EP2012/052674
    Full text -
    link to original document

  4. Poupaert J, Prevost M., Vandevuer S, Van Bambeke F, Colacino E, Tytgat I, Tulkens PM.
    Inibitors of D-Ala-D-Ala-ligase as antibacterial agents.
    Patent number: WO2009080788 (A2); classification: international: C07D263/56; C07D263/00; european: C07D263/56
    Application number: WO2008EP68100 20081219; Priority number(s): EP20070150355 20071221 - International publication date: 2-07-2009
    Full text


No further submission at this stage