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Neuropeptides
demonstrate important functional
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interactions
with monoamines but their effects go
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beyond
modulation of these neurotransmitters
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Neuropeptides
possess a more discrete
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neuroanatomical
localization than monoamines and
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GABA, and thus
might be expected to produce relatively
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little disruption of
normal physiology
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Neuronal
release of neuropeptides requires higher
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stimulation
frequencies than that required by
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monoamine
transmitters colocalized in the same neuron
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