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Catalyse of
recepteur
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autophosphorylation
of
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cytoplasmic
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tyrosine
residues
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àDocking sites for Src
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homology (SH)
and
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phosphotyrosine-binding
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(PTB)
containing molecules
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(PLC, Src, …)
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Recrutment of
additional
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effectors
molecules
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containing SH2, SH3,
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PTB,PH
(pleckstrin) domain
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ðActivation of a cascade of
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intracellular
biochemical
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signals
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