DOPAMINE - RECAPTURE ~ DAT and VMAT2
EFFECTS OF GENETIC MANIPULATIONS
Miller et al
TiPS
20: 424-429 (1999)
Normal animal
DAT knockout
VMAT knockout
Intra
synaptic
concen-
Intra
vesicular
con-
tration of MPP+ and
centration of MPP
dopamine is increased
and dopamine is
decreased
FARM 2146 - 2003-2004