GALANIN
29-30 amino acid neuropeptide
Coexists with noradrenaline in locus coerulus and with 5-HT in the DRN
Found (with its receptors) in limbic regions
Three known G-protein-coupled galanin receptor subtypes (GAL1, GAL2, GAL3)
Blocking the inhibitory effects of galanin on monoamin neurotransmission with galanin receptor antagonists would be predicted to mimic or augment the action of antidepressants
FARM 2146 - 2003-2004