Antitumor activity
•
volume tumor
•
% of surviving mice
of ZD-1839 on
established GEO human
colon carcinoma
xenographs: effet dose
RECEPTOR TYROSINE KINASE INHIBITORS
ACTIVITY - ZD 1839
Ciardiello et al (2000) Clin. Res. Cancer 6: 2053-2063
2003-2004