TARGETS FOR DRUG ACTION
Enzymes
Didanosine, zidovudine
Reverse transcriptase
Saquinavir
HIV protease
Aciclovir
Thymidine kinase
Plasminogen activators
Heparin
Enzymes of blood
clotting cascade
Azathiaprine
Enzymes involved in
DNA synthesis
Cytarabine
Cytarabine
DNA polymerase
Trimethropin
Methotrexate
Dihydrofolate reductase
MPTP
Selegilin
Monoamine oxidase-B
False substrate
Inhibitors
Enzymes
From Pharmacology, Ed Rang et al (2003),
Churchill Livingstone, p 25
2003-2004