NEUROPEPTIDE SYSTEMS AS NOVEL THERAPEUTIC TARGETS FOR DEPRESSION AND ANXIETY DISORDERS
Neuropeptides demonstrate important functional interactions with monoamines but their effects go beyond modulation of these neurotransmitters
Neuropeptides possess a more discrete neuroanatomical localization than monoamines and GABA, and thus might be expected to produce relatively little disruption of normal physiology
Neuronal release of neuropeptides requires higher stimulation frequencies than that required by monoamine transmitters colocalized in the same neuron
FARM 2146 - 2003-2004