2/11/2004
Beta-lactams
6
PBP …
X-ray structure of PBP2x from Streptococcus pneumoniae (Protein data bank accession code 1QMF). The antibiotic cefuroxime is harbored in the transpeptidase domain, whose cleft is reminiscent of class A b-lactamases. The N-terminal domain region may contact other macromolecules in the “divisome” complex.