Inhibiteurs de la 14- a-déméthylase
Text Box: Cl
miconazole (3/4)
inhibition par
recouvrement du
substrat ??
Text Box: lanostérol
Text Box: Cl
3
Text Box: Cl
Recent data: cell growth arrest correlates with the accumulation of 14a-methyl-ergosta-8,24(28)-dien-3b,6a-diol in a
yeast strain with a sterol 14a-demethylase gene disruption, which mimics stringent treatment conditions (Kelly et al.,
B.B.A., 1995, 207:910-915.
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