2/11/2004
FARM 2147
Fluoroquinolones
41
Optimizing dosage for fluoroquinolones
Time (h)
Concentration
MIC
increase the amount administered,
in order to optimize
AUC/MIC
and peak/MIC
Peak/MIC
AUC/MIC
should be > 125
should be > 10
Get both a peak and a AUC !!