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X-ray structure
of PBP2x
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from
Streptococcus
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pneumoniae
(Protein
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data bank
accession
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code 1QMF). The
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antibiotic
cefuroxime is
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harbored in the
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transpeptidase
domain,
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whose cleft is
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reminiscent of
class A b-
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lactamases. The
N-
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terminal domain
region
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may contact other
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macromolecules
in the
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“divisome”
complex.
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