•Dosage
is key to success
•Dosage
should match bacterial sensitivity
•peak,
AUC/MIC are keys to success
•use a
single, appropriate dose for long-life fluoroquinolones (moxifloxacin), or
•repeat
the dose for short-lived fluoroquinolones (all others so far…)
•for fluoroquinolones, the limit is an MIC of
0.5 µg/ml