SAR of frequent side effects
R
R
Ca
++
, Al
+++
, Fe
++
complexation
N
N
HN
HN
R
O
R
Binding to
GABA receptor
5
All FQs
F
COO
-
N
cipro,
grepa ...
N
7
8
R
Inhibition of P450
1
C
sparflo,
flero,
lomeflo
Inhibition of P450
F
Phototoxicity
33