2/11/2004
FARM 2147 Fluoroquinolones
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Take home” message
•Dosage is key to success
•Dosage should match bacterial sensitivity
•peak, AUC/MIC are keys to success
•use a single, appropriate dose for long-life fluoroquinolones (moxifloxacin), or
•repeat the dose for short-lived fluoroquinolones (all others so far…)
•for fluoroquinolones, the limit is an MIC of
0.5 µg/ml