2/11/2004
Beta-lactams
PBP
…
X-ray structure of PBP2x from Streptococcus pneumoniae
(Protein data bank accession code 1QMF). The antibiotic
cefuroxime is harbored in the transpeptidase domain, whose cleft is reminiscent of
class A b-lactamases. The N-terminal domain region may contact other macromolecules
in the “divisome” complex.
