TARGETS FOR DRUG ACTION
Ions-channels
Dizocilpine, Mg 2+ , Ketamine
Glutamate-gated (NMDA)
cation channels
GABA-gated chloride channels
Cromokalim
Sulphonylureas
ATP-sensitive potassium
channels
Voltage-gated potassium
channels
Dihydropyridines
b-adrenoreceptor agonists
Voltage-gated calcium channels
Renal tubule sodium channels
Local anaesthetics
Tetrodotoxin
Voltage-gated sodium channels
From Pharmacology- Ed Rang et al (2003)-Churchill Livingstone, p 24
2003-2004