RECEPTEURS NMDA
A protonated H+-sensor stabilizes
the NR1-NR2B heterodimer in  low-
conductance state
Polyamines (spermine, spermidine)
shield the H+-sensor from protons
thus attenuating the inhibition by
proton  and potentialising the influx
of Ca 2+
Ifenprodil enhances the sensitivity
to protons
From Chizh et al.  TiPS 22: 636-642 (2001)
FARM 2146 - 2003-2004