2/11/2004
FARM 2147 Fluoroquinolones
15
From norfloxacin to the other 1st generation fluoroquinolones: pefloxacin
-
H
3
C
N
pefloxacin *
Add a methyl
to still increase
half-life
* Ger. pat. 2,840,910 to
   Roger Bellon/Dainippon,1979
O
O
norfloxacin
N
C
F
O
-
HN
N
CH
3
O
O
N
C
F
O
-
N
CH
3