Pseudomonas and penem efflux

Okamoto et al. J. Infect. Chemother (2002) 8: 371-373

Okamoto et al. AAC (2002) 46:2696-2699

MERO IMI BIA PANI FARO RITI

AB CD XY

- - -

+ * - -

++ - -

- ++ -

- - ++

0.032 0.25 0.25 0.25 1 2

0.25 1 0.5 4 512 128

1 0.25 0.25 1 4096 256

0.25 0.125 0.063 0.25 16 4

0.063 0.25 0.25 2 4 8

* clinical isolate, basal level of expression

Mex pumps

MICs