In which indications could they be useful ?
- which organs ?
- severe skin and soft tissues
- septicemia / deep organs
- endocarditis (combination ?)
- CNS infections (penetration ?)
- which organisms ?
- MRSA certainly YES
- VRE oritavancin only
- VISA limited activity,
… but synergy for dalba + ?-lactam
- S. pneumo other alternatives