Dissocier les co-variables pharmacocinétiques

0

100

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500

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0

4

8

12

16

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24

Temps (h)

Concentration, ng/mL

uniquotid.

3 x / jour

CMI 90

Pic / MIC ? ?

T > MIC ? ?

AUC / MIC =

Adapté de F. O. Ajayi, ISAP-FDA Workshop, 1999

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