Fluoroquinolones : get both a peak and an AUC !

• 24h-AUC / MIC must be ? 125 * (Schentag, ...)

• 24h-AUC is proportional to the daily dose
  ? adjust the daily dose
  

• peak must be ? 10 * (Drusano, ...)

• peak is proportional to the unit dose…
  ? adjust the unit dose
  

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