PK/PD patterns of antimicrobial activity (2 of 3) (after WA. Craig, 2000)

* 2d ISAP Educational Workshop,

Stockholm, Sweden, 2000

2. Antibiotics with time-dependent killing, but  also prolonged persistent effects 

Key PK/PD parameter

24 h AUC / MIC

ratio

Goal

Optimize the

amount of drug

administered

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