Degradation pathways of ceftazidime (24h in aqueous media)

[(2–amino–4-thiazolyl) (1–carboxy–1–methyletoxy) imino] acetyl–ethanal.

?2-isomer

cefazidime

> 25 °C

Pyridine *

* < 50 mg from an amount of 4 g in 24h at temp < 25°C

Ring opening

Servais & Tulkens, AAC, in press

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