The severity of AG-induced regeneration (top) and apoptosis (bottom) at “clinical doses” varies among derivatives ...

TUNEL (+) nuclei DNA specific

(no./sq mm) radioactivity

0

50

100

150

a,d

a,d

b,d

a

b

0

20

40

60

80

a

b

c

d

d

ct gm nt is am

El Mouedden et al., 2000

ct = control

gm = gentamicin (10mg)

nt = netilmicin (10 mg)

is = isepamicin (40 mg)

am = amikacin (40 mg)

Previous slide

Next slide

Back to first slide

View graphic version