ASC24h / MIC = 125 ET Pic / CMI > 10 comme paremaètres fixant la limite de sensibilité aux FQ

Pt crit. PK/PD (mg/L)

FQ Dose ASC/CMI pic / MIC

(mg/24h) (24h)

norfloxacine 800 0.1 0.2

ciprofloxacine 500 0.1 0.2

ofloxacine 400 0.2-0.4 0.3 - 0.4

levofloxacine 500 0.4 0.4 - 0.5

gatifloxacine 400 0.3 0.4

moxifloxacine 400 0.4 0.4

* US prescrib. inf. (adult of 60 kg) of NOROXIN®, CIPRO®, FLOXIN®, LEVAQUIN®, TEQUIN®  and AVELOX®

NCCLS Bkpt

(mg/L)

4

1

2

2

2

2

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