Effect of IL-1 and dexamethasone on human fibroblast COX activity

1600

1200

800

400

0

Control

IL-1

IL-1 + Dex

COX Activity

Fibroblasts

• +/- IL-1

• +/- Dex

• -> 8 hr

• -> AA

Raz et al, PNAS, 86,1657-1661

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