Most patients are asymptomatic prior to a serious NSAID-associated GI event ...

N = 141

N = 1,921

Armstrong &Blower.

Gut. 1987;28:527–532.

Singh et al.

Arch Intern Med.

1996;156:1530-1536.

Without

symptoms

With

symptoms

42%

58%

81%

19%

Bleeding, perforation, and gastric outlet obstruction