Adapting ?-lactam dosages based on AUC24h / MIC

0.5 g 12 h 1 g 250 2

1 g 12 h 2 g 500 4

1 g 8 h 3 g 750 6

1 g 6 h 4 g 1000 8

1 g 4 h 6 g 1250 10

Increase the frequency, not the unit dose …

(you need to get the time > MIC)