PK/PD: role of concentration Point of Principle an example with Listeria monocytogenes
multiples of MIC
bacterial killing (log reduction)
Quinolone
(sparfloxacin)
Macrolide
(azithromycin)
?-lactam
(ampicillin)
Ouadrhiri et al., Antimicrob. Agents Chemother., 1999
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