?-lactam antiotics
Key works of Paul J. Claes (cephalosporins and penems)
Claes PG, Decoster G, Kerremans LA, Vanderhaeghe H. Preparation of delta 3-7 alpha-phenylacetamidodesacetoxycephalosporanic acid. J Antibiot (Tokyo). 1979 Aug;32(8):820-7.
Frere JM, Kelly JA, Klein D, Ghuysen JM, Claes P, Vanderhaeghe H. Delta 2- and delta 3-cephalosporins, penicillinate and 6-unsubstituted penems. Intrinsic reactivity and interaction with beta-lactamases and D-alanyl-D-alanine-cleaving serine peptidases. Biochem J. 1982 Apr 1;203(1):223-34.
Herdewijn P, Claes PJ, Vanderhaeghe H. Synthesis of delta 3-1-methylene-1-carbacephems. J Med Chem. 1986 May;29(5):661-4.