Aminoglycoside nephrotoxicity: understanding the molecular mechanism...
The work of Paul J. Claes ...
Carlier MB, Laurent G, Claes PJ, Vanderhaeghe HJ, Tulkens PM. Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies. Antimicrob Agents Chemother. 1983 Mar;23(3):440-9.
Brasseur R, Carlier MB, Laurent G, Claes PJ, Vanderhaeghe HJ, Tulkens PM, Ruysschaert JM. Interaction of streptomycin and streptomycylamine derivatives with negatively charged lipid layers. Correlation between binding, conformation of complexes and inhibition of lysosomal phospholipase activities. Biochem Pharmacol. 1985 Apr 1;34(7):1035-47.
Kishore BK, Van Schepdael A, Laurent G, Lambricht P, Claes PJ, Piret J, Tulkens PM, Maldague P. Co-oxydextran as a protectant against gentamicin-induced renal lysosomal phospholipidosis andfocal tubular necrosis. Perspectives and limitations. Contrib Nephrol. 1993;101:213-9.