Pharmacokinetics / Pharmacodynamics in action: adusting the dose of a FQ for an MIC

Daily dosage of AUC MIC for an

ciprofloxacine AUC24h/MIC = 125

400 11 0.1

800 22 0.2

1200 33 0.3

* based on narmal half-lifes; doses for an adult of 60 kg

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