Most frequent antibiotic-pumps in procaryotes (2/2)

TOPOLOGY

MECHANISM

ANTIBIOTICS

14 TMS

12 TMS

• Major Facilitator Superfamily (Gram positive / negative)

H

+

H

+

tetracyclines

fluoroquinolones

macrolides

lincosamides

rifampicin

pristinamycin

chloramphenicol

aminoglycosides

+

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