Conclusions (3/3) ...
In the absence of etiologic diagnostic or knowledge of likely MIC …
teicoplanin should probably be used
- at 6 mg / (kg x d) only with suspected sensitive organisms (MIC < 0.5 g/L) and non-life-threatening situations;
- at 9 or even 12 mg / (kg x d) in severe cases (S. aureus sepsis, …), but lack of well-controlled clinical trials