"1st generation" fluoroquinolones

N

C

O

F

O

-

O

HN

N

-

H

3

C

piperazine

N

C

O

O

-

O

HN

N

N

C

O

O

-

O

N

N

CH

3

CH

3

F

F

norfloxacin

ciprofloxacin

pefloxacin

O

CH

3

-

H

3

C

N

C

O

O

-

O

N

N

F

ofloxacin

methyl

cyclo

propyl

morpholine

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