%PDF-1.4
%
1 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
5 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
13 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
7 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
9 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
11 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
6 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
10 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
3 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
8 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
12 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
4 0 obj
<>>>/BBox[0 0 609.45 793.7]/Length 56>>stream
xs
w3T04PI2P0T5T0 q-,LBr44C@ i s
I-
endstream
endobj
15 0 obj
<>stream
application/pdf
10.1080/14787210.2017.1338139
en
Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?
Isabelle K. Delattre
Fabio S. Taccone
Frédérique Jacobs
Maya Hites
Thierry Dugernier
Herbert Spapen
Pierre-François Laterre
Pierre E. Wallemacq
Françoise Van Bambeke
Paul M. Tulkens
Taylor & Francis
Expert Review of Anti-infective Therapy, 2017. doi:10.1080/14787210.2017.1338139
Β-lactams
critically-ill patients
PK/PD targets
first dose
maximal efficacy
Journal
Expert Review of Anti-infective Therapy
© 2017 Informa UK Limited, trading as Taylor & Francis Group
1478-7210
1744-8336
15
7
677
688
10.1080/14787210.2017.1338139
https://doi.org/10.1080/14787210.2017.1338139
VoR
2017-07-07T11:52:54+05:30
Arbortext Advanced Print Publisher 11.0.3433/W Unicode
2017-07-08T00:22:17-07:00
2017-07-08T00:22:17-07:00
Β-lactams; critically-ill patients; PK/PD targets; first dose; maximal efficacy
iText 4.2.0 by 1T3XT
uuid:5cdca61f-2b6f-4417-aeba-7cd785485b7f
uuid:fd082f74-8a12-4ffe-ac22-3c9a373545a7
2017-06-19truewww.tandfonline.com10.1080/14787210.2017.1338139www.tandfonline.comtrue2017-06-1910.1080/14787210.2017.1338139
endstream
endobj
16 0 obj
<>stream
x+ |
endstream
endobj
17 0 obj
<>stream
xS**T0T0 Bi yw*
endstream
endobj
18 0 obj
<>stream
x+ |
endstream
endobj
19 0 obj
<>stream
xS**T0T0 Bi y\'
endstream
endobj
20 0 obj
<>stream
x+ |
endstream
endobj
21 0 obj
<>stream
xS**T0T0 Bi yS&
endstream
endobj
22 0 obj
<>stream
x+ |
endstream
endobj
23 0 obj
<>stream
xS**T0T0 Bi yA$
endstream
endobj
24 0 obj
<>stream
x+ |
endstream
endobj
25 0 obj
<>stream
xS**T0T0 Bih lT
endstream
endobj
26 0 obj
<>stream
x+ |
endstream
endobj
27 0 obj
<>stream
xS**T0T0 Bih uU
endstream
endobj
28 0 obj
<>stream
x+ |
endstream
endobj
29 0 obj
<>stream
xS*
R
endstream
endobj
30 0 obj
<>stream
x+ |
endstream
endobj
31 0 obj
<>stream
xS**T0T0 Bi y,
endstream
endobj
32 0 obj
<>stream
x+ |
endstream
endobj
33 0 obj
<>stream
xS**T0T0 Bi ye(
endstream
endobj
34 0 obj
<>stream
x+ |
endstream
endobj
35 0 obj
<>stream
xS**T0T0 Bi y8#
endstream
endobj
36 0 obj
<>stream
x+ |
endstream
endobj
37 0 obj
<>stream
xS**T0T0 Bi yJ%
endstream
endobj
38 0 obj
<>stream
x+ |
endstream
endobj
39 0 obj
<>stream
xS**T0T0 Bi yn)
endstream
endobj
40 0 obj
<>stream
x+ |
endstream
endobj
41 0 obj
<>stream
xS**T0T0 Bi y+
endstream
endobj
43 0 obj
<>stream
xɎ/i ͱ`bYhq|~U$oF"I&owh%d;6/G^~>_zds~/Z۫^gK,5G6,4}ȿ<.kzoNpusdk\Ōn8 zo[WY+l̋7;pzv=[F6S9/1,9H
eB1wHgٯ봇ðDEB]/j.^TR/D^--o_,||/T|Ǐ1/i^S/oZ;H?3|\QT ]/x !`6|f%e=aׇ?7lR
C(IeҢP(%+R^SRB ^YPLSZBb}ʗxd*Hx̨ /cUzTvK*ЫbDFYlz6baue43.-
հ!jZ%Z-mi'Vyzi"RJ/ ]ѼYTυ6^!^S&lJ0Q&2b9D
C\
H`fBO HK@:nq0
;w%EWLY!@1PĄP ". )儷>a,Z(ʁNb1,ѐ\%D̶ϥ1
6(vwJoXn71>up|7|͑۟}d&f0)4#>S^r̾k%
2a5"O2U}lC [m*?,F:k5k|P<|~e%nkC`!~b?zϰ7DeI丫,7P@AF{pfFxXпƟʒOŗ9^; `]U2V$\hs3l} Cs֬k6<'1Ӡ@ţ:a=n]%oBNBBvE®&GW:H
΅a1?
|N|
4|ǼGa'qc8oSZ_85O`Y1c騮%UԙҬheƚ sdҲ˹k&Noӂ?Ԋ G$D|q@@x10}J?N0YdH ͘%}v6&nMŬm%ΘI)p\IۜL㶰M\ DO?Y")yC>