Curricula
vitae of the members of the Unit
of Cellular and Molecular Pharmacology
Université catholique de Louvain (UCL-Bruxelles)
Louvain Drug Research Institute (Department
of Pharmaceutical Sciences)
Cellular and Molecular Pharmacology Unit
Mingeot-Leclercq Marie-Paule
PROFESSIONAL ADDRESS
Catholic University of
Louvain (UCL)
Louvain Drug Research Institute
Department of Pharmaceutical Sciences
Unit of Cellular and molecular pharmacology
UCL 7370 Avenue E. Mounier Bt B1.73.05
1200 Brussels (Belgium)
Te: 32-2-764.73.74
Fax: 32-2-764.73.73
Email:marie-paule.mingeot@uclouvain.be
EDUCATION
- Habilitation (Thèse
d'Agrégation de l'Enseignement Supérieur) (2000; UCL)
- PhD in Pharmaceutical
Sciences) (1988; UCL)
- Pharmacist (1982; UCL)
- Master in Sciences (MSc
in Chemistry) (1979; UCL)
POSITIONS
- 2008 - : Full Professor
(Professeur ordinaire) at the Catholic University of Louvain, Brussels, (Belgium);
- 2002-2008: Professor
at the Catholic University of Louvain, Brussels, (Belgium);
- 2007-2009: Invited Professor
à l'Université Joseph Fourier de Grenoble - Département
de Pharmacochimie, Grenoble (France);
- 2001-2002: FNRS Senior
Research Associate at the Department of Pharmaceutical Sciences, Brussels,
(Belgium);
- 1991-2001: FNRS Research
Associate at the Department of Pharmaceutical Sciences, Brussels, (Belgium);
- 1987-1991: FNRS Postdoctoral
fellow at the Institute of Cellular Pathology, Brussels, (Belgium);
- 1984-1987: Doctoral fellow
at the Institute of Cellular Pathology, Brussels, (Belgium);
- 1982-1984: Assistant
at the University of Mostaganem (Algeria)
MAIN INSTITUTIONAL RESPONSABILITIES
- Head of the Louvain Drug
Research Institute (2009 -)
- Head of the School of
Pharmacy (2007-2009)
- Head of the Cellular
and Molecular Pharmacology Research Group (2003 -)
- Academic Secretary of
the School of Pharmacy (2002-2007)
- Member for Committee
for Academic Promotion at UCL - Health Sector (2009-2011)
TEACHING ACTIVITIES
- At UCL Université
Catholique de Louvain)
- Biochimie et biologie
moléculaire
- Biophysique appliquée
aux médicaments
- Introduction au monde
pharmaceutique, y compris stage
- Pharmacologie générale
(2° partie)
- Pharmaco-chimie et
pharmacologie prospective
- Formation à
la Recherche et Séminaires de Recherche en Sciences pharmaceutiques
- Pharmacologie moléculaire
- As Invited Professor
(2007-2009) at Université Joseph Fourier, Grenoble, France
- As Lecturer at
- the Université
du Saint-Esprit , Kaslik, Liban
- the Faculty of Sciences,
Université Joseph Fourier, Grenoble , France (2009-2013)
RESEARCH ACTIVITIES
Main Research Interest
- Caracterization of
the interactions between drugs (mostly antibacterials) and lipid membranes
- Consequences of the
interactions between drugs and lipid membrane on
- the biophysical
properties of membranes (permeability, ability to fuse, lateral and
transversal organization of lipids, bending modulus
.)
- the passage of
peptides or drugs through membranes
- the lysosomal
phospholipase activity and the integrity of subcellular organites (lysosomes)
- Cross talk between
subcellular organites and apoptosis (Role of Lysosomes, mitochondria, endoplasmic
reticulum, proteasome) in apoptosis induced by aminoglycoside antibiotics.
- Design, evaluation
and investigation at the molecular level, of new antibacterials
Promotor of
- 5 postdoctoral fellows
- 9 PhD in Sciences or
Biomedical and Pharmaceutical Sciences
- 7 DEA in Pharmaceutical
Sciences
- 50 Masters in Sciences
(or Equivalent)
- 10 Erasmus students
Member of the jury for
pHD thesis (~ 60 thesis)
Principal Investigator
for research contracts including
- 8 contracts from UCL,
including 2 Concerted Research Action
- 17 contracts with FNRS
(Fonds National de la Recherche scientifique), FRSM,FRSC,Télévie,Crédits
aux chercheurs
- 6 contracts with Regions
- 2 contracts with Vaincre
les maladies lysosomales
- 3 industrial contracts
Author of
- 9 reviews
- 5 chapters of books
- 83 articles (peer reviewed-
Mean IF > 3.5)
- 154 posters in international
congress
Regular reviewer for
- Archives of Toxicology
- Biochemica Biophysica
Acta (Biomembranes)
- Cell Biology and Toxicology
- Chem. Phys. Chem.
- Clin. Exp. Pharmacol.
Physiol.
- Current Medicinal Chemistry
- European Journal of
Medicinal Chemistry
- Journal of Medicinal
Chemistry
- Langmuir
- Nanotechnology
- Pharmaceutical Research
- Thermochimica Acta
Expert at
- FWO (Fonds Wetenschappelijk
Onderzoek; Research Foundations - Flanders): 2007-2012; 2012-2015)
- ANR (Agence Nationale
de la Recherche - France) Section: Physique et chimie du vivant
- CEE: Sixth framework
program (women in Science decision making)
MISCELLANEOUS
Memberships
- Pharma Louvain,
- Association des chimistes
de Louvain
- American Biophysical
Society
- Belgian Pharmaceutical
Society
Expert at CEE FP7 - Getting
more women to the top in research
Last update: January 2013