PROFESSIONAL ADDRESS

Catholic University of Louvain (UCL)
Louvain Drug Research Institute
Department of Pharmaceutical Sciences
Unit of Cellular and molecular pharmacology
UCL 7370 Avenue E. Mounier Bt B1.73.05
1200 Brussels (Belgium)
Te: 32-2-764.73.74
Fax: 32-2-764.73.73
Email:marie-paule.mingeot@uclouvain.be

EDUCATION

• Habilitation (Thèse d'Agrégation de l'Enseignement Supérieur) (2000; UCL)
• PhD in Pharmaceutical Sciences) (1988; UCL)
• Pharmacist (1982; UCL)
• Master in Sciences (MSc in Chemistry) (1979; UCL)

POSITIONS

• 2008 - : Full Professor (Professeur ordinaire) at the Catholic University of Louvain, Brussels, (Belgium);
• 2002-2008: Professor at the Catholic University of Louvain, Brussels, (Belgium);
• 2007-2009: Invited Professor à l'Université Joseph Fourier de Grenoble - Département de Pharmacochimie, Grenoble (France);
• 2001-2002: FNRS Senior Research Associate at the Department of Pharmaceutical Sciences, Brussels, (Belgium);
• 1991-2001: FNRS Research Associate at the Department of Pharmaceutical Sciences, Brussels, (Belgium);
• 1987-1991: FNRS Postdoctoral fellow at the Institute of Cellular Pathology, Brussels, (Belgium);
• 1984-1987: Doctoral fellow at the Institute of Cellular Pathology, Brussels, (Belgium);
• 1982-1984: Assistant at the University of Mostaganem (Algeria)

MAIN INSTITUTIONAL RESPONSABILITIES

• Head of the Louvain Drug Research Institute (2009 -)
• Head of the School of Pharmacy (2007-2009)
• Head of the Cellular and Molecular Pharmacology Research Group (2003 -)
• Academic Secretary of the School of Pharmacy (2002-2007)
• Member for Committee for Academic Promotion at UCL - Health Sector (2009-2011)

TEACHING ACTIVITIES

• At UCL Université Catholique de Louvain)
• Biochimie et biologie moléculaire
• Biophysique appliquée aux médicaments
• Introduction au monde pharmaceutique, y compris stage
• Pharmacologie générale (2° partie)
• Pharmaco-chimie et pharmacologie prospective
• Formation à la Recherche et Séminaires de Recherche en Sciences pharmaceutiques
• Pharmacologie moléculaire
  
  
• As Invited Professor (2007-2009) at Université Joseph Fourier, Grenoble, France
  
  
• As Lecturer at
• the Université du Saint-Esprit , Kaslik, Liban
• the Faculty of Sciences, Université Joseph Fourier, Grenoble , France (2009-2013)

RESEARCH ACTIVITIES

Main Research Interest

• Caracterization of the interactions between drugs (mostly antibacterials) and lipid membranes
• Consequences of the interactions between drugs and lipid membrane on
  • the biophysical properties of membranes (permeability, ability to fuse, lateral and transversal organization of lipids, bending modulus….)
  • the passage of peptides or drugs through membranes
  • the lysosomal phospholipase activity and the integrity of subcellular organites (lysosomes)
• Cross talk between subcellular organites and apoptosis (Role of Lysosomes, mitochondria, endoplasmic reticulum, proteasome) in apoptosis induced by aminoglycoside antibiotics.
• Design, evaluation and investigation at the molecular level, of new antibacterials

Promotor of

• 5 postdoctoral fellows
• 9 PhD in Sciences or Biomedical and Pharmaceutical Sciences
• 7 DEA in Pharmaceutical Sciences
• 50 Masters in Sciences (or Equivalent)
• 10 Erasmus students

Member of the jury for pHD thesis (~ 60 thesis)

Principal Investigator for research contracts including

• 8 contracts from UCL, including 2 Concerted Research Action
• 17 contracts with FNRS (Fonds National de la Recherche scientifique), FRSM,FRSC,Télévie,Crédits aux chercheurs
• 6 contracts with Regions
• 2 contracts with Vaincre les maladies lysosomales
• 3 industrial contracts

Author of

• 9 reviews
• 5 chapters of books
• 83 articles (peer reviewed- Mean IF > 3.5)
• 154 posters in international congress

Regular reviewer for

• Archives of Toxicology
• Biochemica Biophysica Acta (Biomembranes)
• Cell Biology and Toxicology
• Chem. Phys. Chem.
• Clin. Exp. Pharmacol. Physiol.
• Current Medicinal Chemistry
• European Journal of Medicinal Chemistry
• Journal of Medicinal Chemistry
• Langmuir
• Nanotechnology
• Pharmaceutical Research
• Thermochimica Acta…

Expert at

• FWO (Fonds Wetenschappelijk Onderzoek; Research Foundations - Flanders): 2007-2012; 2012-2015)
• ANR (Agence Nationale de la Recherche - France) Section: Physique et chimie du vivant
• CEE: Sixth framework program (women in Science decision making)

MISCELLANEOUS

Memberships

• Pharma Louvain,
• Association des chimistes de Louvain
• American Biophysical Society
• Belgian Pharmaceutical Society

Expert at CEE FP7 - Getting more women to the top in research